Pritzlaff, Scott G Jung, Michael Singh, Naileshni Cho, Juliann Skoblar, Matthew Jagtiani, Manoj Prasad, Ravi Leong, Michael S Salmasi, Vafi
Published in
Neuromodulation : journal of the International Neuromodulation Society
Neuromodulation represents one of the more advanced tools in the armamentarium of pain physicians. To optimize neuromodulation patient selection and management, an institutional interdisciplinary neuromodulation committee was created at each of two academic medical centers (University of California Davis [UCD] and Stanford University). The committe...
Hodkinson, Duncan J Drabek, Marianne M Jung, JeYoung Lankappa, Sudheer T Auer, Dorothee P
Published in
Neuromodulation : journal of the International Neuromodulation Society
Many chronic pain conditions show evidence of dysregulated synaptic plasticity, including the development and maintenance of central sensitization. This provides a strong rationale for neuromodulation therapies for the relief of chronic pain. However, variability in responses and low fidelity across studies remain an issue for both clinical trials ...
Southerland, Warren Hussain, Nasir Qing, Ruan Shankar, Puja Surapaneni, Sindhuja Burns, James Mahmood, Syed Yazdi, Cyrus Abdel-Rasoul, Mahmoud Simopoulos, Thomas T
...
Published in
Neuromodulation : journal of the International Neuromodulation Society
This study aimed to determine agreement between reported percentage pain reduction (RPPR) and calculated percentage pain reduction (CPPR) in patients with percutaneous spinal cord stimulation (SCS) implants, and to correlate RPPR and CPPR with patient satisfaction. We also sought to determine which patient-reported outcome measures are most improve...
Hoffmann, Chelsey M Butler, Casey S Pingree, Matthew J Moeschler, Susan M Mauck, William D D'Souza, Ryan S
Published in
Neuromodulation : journal of the International Neuromodulation Society
This study aimed to assess whether patient response to targeted diagnostic peripheral nerve block before peripheral nerve stimulator (PNS) device implantation is associated with efficacy after PNS implantation. The electronic medical records from the Mayo Clinic Enterprise (three quarternary care medical centers and additional satellite medical cen...
Venkatraman, Vishal Futch, Brittany G Bartlett, Alyssa Yang, Lexie Z Lee, Hui-Jie Shofty, Ben Parente, Beth A Lad, Shivanand P Williamson, Theresa L Rahimpour, Shervin
...
Published in
Neuromodulation : journal of the International Neuromodulation Society
Epilepsy affects 1% to 2% of the global population, and those who are resistant to medical treatment may be candidates for neuromodulation. In select populations, brain stimulation approaches including deep brain stimulation (DBS) and responsive neurostimulation (RNS) are used. Although studies have shown that patients from Black, Hispanic, lower i...
Li, Hongzhu Lai, Lanfeng Li, Xin Wang, Runyi Fang, Xiaoling Xu, Nenggui Zhao, Jiaying
Published in
Neuromodulation : journal of the International Neuromodulation Society
γ-amino butyric acid (GABA)-ergic dysfunction in excitatory and inhibitory (E/I) imbalance drives the pathogenesis of Alzheimer's disease (AD). Inhibitory interneurons play an important role in the regulation of E/I balance, synaptic transmission, and network oscillation through manipulation of GABAergic functions, showing positive outcomes in AD a...
Angeli, Claudia Rejc, Enrico Boakye, Maxwell Herrity, April Mesbah, Samineh Hubscher, Charles Forrest, Gail Harkema, Susan
Published in
Neuromodulation : journal of the International Neuromodulation Society
This is a report of methods and tools for selection of task and individual configurations targeted for voluntary movement, standing, stepping, blood pressure stabilization, and facilitation of bladder storage and emptying using tonic-interleaved excitation of the lumbosacral spinal cord. This study aimed to present strategies used for selection of ...
Zhang, Shuhui Zhang, Can Yan, Hui Yang, Lijuan Shi, Ning Liu, Chengxia Chen, Yan
Published in
Neuromodulation : journal of the International Neuromodulation Society
Inflammatory bowel disease (IBD) is characterized by chronic progressive intestinal inflammation. Sacral nerve stimulation (SNS) ameliorates colon inflammation caused by IBD. The aim of this study was to investigate the antiinflammatory benefits of SNS in colitis rats and explore the roles of the cholinergic antiinflammatory pathway, macrophage aut...
Li, Yingli Song, Shuangning An, Jing Liu, Shi
Published in
Neuromodulation : journal of the International Neuromodulation Society
Electroacupuncture (EA) at Zusanli (ST36) is an alternative treatment for several gastrointestinal motility disorders; however, the exact mechanism is unconfirmed. We aimed to show the potential effects of EA on muscularis macrophages (MMφ), the bone morphogenetic protein (BMP)/BMP receptor (BMPR)-Smad signal pathway, and enteric neurons in diabeti...
Guo, Yu Gharibani, Payam
Published in
Neuromodulation : journal of the International Neuromodulation Society
The aims of this study were to investigate analgesic effects of vagus nerve stimulation (VNS) on visceral hypersensitivity (VH) in a rodent model of functional dyspepsia (FD) and to compare invasive VNS with noninvasive auricular VNS (aVNS). Eighteen ten-day-old male rats were gavaged with 0.1% iodoacetamide (IA) or 2% sucrose solution for six days...
