Neuroepidemiology Special Issue: Population-Based Epidemiological Studies of Neurological Disorders
Published in Neuroepidemiology
Global, Regional and Country-Specific Burden of Ischaemic Stroke, Intracerebral Haemorrhage and Subarachnoid Haemorrhage...
Published in Neuroepidemiology
Background: Stroke is a leading cause of death and disability in globally and particularly in low- and middle-income countries, and this burden is increasing. The burden of stroke pathological subtypes varies in terms of incidence, disability and mortality. Previous Global Burden of Diseases, Injuries, and Risk Factors Studies (GBD) reports did not...
Risk of Mortality in Immigrants with Multiple Sclerosis in Ontario, Canada
Published in Neuroepidemiology
Introduction: Little is known about how mortality in multiple sclerosis (MS) may differ based on sociodemographic factors, such as immigrant status. We compared mortality in immigrants versus long-term residents with MS in Ontario, Canada. Methods: In this retrospective cohort study, we applied a validated algorithm to linked, population-based immi...
“Essential Tremor Plus”: A Problematic Concept: Implications for Clinical and Epidemiological Studies of Essential Tremo...
Published in Neuroepidemiology
Background: An issue of central importance for most neurological disorders is that of case definition. In the field of neuroepidemiology, case definition informs the design, conduct, and interpretation of research studies that range from observational to interventional studies, from case-control to cohort studies, and from descriptive to analytical...
Dementia Research Fit for the Planet: Reflections on Population Studies of Dementia for Researchers and Policy Makers Al...
...Published in Neuroepidemiology
In recent years, a rapidly increasing collection of investigative methods in addition to changes in diagnostic criteria for dementia have followed “high-tech” trends in medicine, with the aim to better define the dementia syndrome and its biological substrates, mainly in order to predict risk prior to clinical expression. These approaches are not w...
Feasibility of Using a Nationally Representative Telephone Survey to Monitor Multiple Sclerosis Prevalence in the United...
...Published in Neuroepidemiology
Background: Multiple sclerosis (MS) is the most common chronic neurologic disease of young adults, placing a heavy burden on patients, families, and the healthcare system. Ongoing surveillance of the incidence and prevalence of MS is critical for health policy and research, but feasible options are limited in the United States and many other countr...
Interrogation of the Multiple Sclerosis Prodrome Using High-Dimensional Health Data
Published in Neuroepidemiology
Background: There is growing evidence of a prodromal period in multiple sclerosis (MS). A better understanding of the prodrome may facilitate prompt recognition and treatment of MS as well as narrowing of the etiologically relevant period when searching for MS risk factors. Objectives: To explore and further delineate the MS prodrome, we used stat...
Incidence of Sports-Related Traumatic Brain Injury of All Severities: A Systematic Review
Published in Neuroepidemiology
Introduction: Whilst there are many benefits to participating in sports and recreational activities, there is also a risk of injury including sports-related traumatic brain injury (SR-TBI). To inform injury prevention initiatives, it is important to explore the burden of SR-TBI at the population level. This review aimed to estimate the incidence o...
The Reconstructed Cohort Design: A Method to Study Rare Neurodegenerative Diseases in Population-Based Settings
Published in Neuroepidemiology
Rare neurodegenerative diseases are characterized by high heterogeneity and high clinical complexity, as well as low incidence and prevalence, thus making tracking small numbers of incident cases in the general population very challenging. Since it is not possible to use classical cohort studies to estimate the incidence of these rare diseases, we ...
Spatial Epidemiology of Sporadic Creutzfeldt-Jakob Disease in Apulia, Italy
...Published in Neuroepidemiology
Background: Sporadic Creutzfeldt-Jakob disease (CJD) is a rare neurodegenerative disease caused by prions that is randomly distributed in all countries, with an overall yearly mortality rate of about 1–2 cases per million people. On a few occasions, however, sporadic CJD occurred with higher than expected rates, but further investigations failed to...
