New Developments in Reproductive and Stress Neuroendocrinology
Published in Neuroendocrinology
Emerging Roles of Anti-Müllerian Hormone in Hypothalamic-Pituitary Function
Published in Neuroendocrinology
Since its initial discovery in the 1940s, research into the physiological actions of anti-Müllerian hormone (AMH), from its eponymous role in male developmental biology to its routine clinical use in female reproductive health, has undergone a paradigm shifting change. With several exciting studies recently reporting hitherto unforeseen AMH actions...
Preface
Published in Neuroendocrinology
Clinical, Pathological, and Molecular Factors of Aggressiveness in Lactotroph Tumours
Published in Neuroendocrinology
The behaviour of lactotroph tumours varies between benign tumours, those cured by treatment, and that of aggressive tumours, and carcinomas with metastasis. Identification of clinical, pathological and molecular factors is essential for the early identification of patients that may have such aggressive tumours. Plasma prolactin levels and tumour si...
Response to Prof. Ingo Brink and Prof. Aubalewska-Dydejczyk regarding Their “Letter to the Editor”
Published in Neuroendocrinology
Comment on Sundin et al.: ENETS Consensus Guidelines
Published in Neuroendocrinology
Pitfalls in the Diagnostic Evaluation of Hyperprolactinemia
Published in Neuroendocrinology
An appropriate diagnostic evaluation is essential for the most appropriate treatment to be performed. Currently, macroprolactinemia is the third most frequent cause of nonphysiological hyperprolactinemia after drugs and prolactinomas. Up to 40% of macroprolactinemic patients may present with hypogonadism symptoms, infertility, and/or galactorrhea. ...
Sex differences in Hippocampal Memory and Learning following Neonatal Brain Injury: Is There a Role for Estrogen Recepto...
Published in Neuroendocrinology
Neonatal encephalopathy due to hypoxia-ischemia (HI) leads to severe, life-long morbidities in thousands of neonates born in the USA and worldwide each year. Varying capacities of long-term episodic memory, verbal working memory, and learning can present without cerebral palsy and have been associated with the severity of neonatal encephalopathy su...
The Role of 11β-Hydroxy Steroid Dehydrogenase Type 2 in Glucocorticoid Programming of Affective and Cognitive Behaviours...
Published in Neuroendocrinology
Developmental exposure to stress hormones, i.e. glucocorticoids, is central to the process of prenatal programming of later-life health. Glucocorticoid overexposure, through stress or exogenous glucocorticoids, results in a reduced birthweight, as well as affective and neuropsychiatric outcomes in adults, combined with altered hypothalamus-pituitar...
Corticosteroid Action in the Brain: The Potential of Selective Receptor Modulation
Published in Neuroendocrinology
Glucocorticoid hormones have important effects on brain function in the context of acute and chronic stress. Many of these are mediated by the glucocorticoid receptor (GR). GR has transcriptional activity which is highly context-specific and differs between tissues and even between cell types. The outcome of GR-mediated transcription depends on the...
