Zouaoui, S Darlix, A Rigau, V Mathieu-Daudé, H Bauchet, F Bessaoud, F Fabbro-Peray, P Trétarre, B Figarella-Branger, D Taillandier, L
...
Published in
Neuro-Chirurgie
Given the number of meningiomas not histologically-validated, we can estimate that the gross incidence rate for meningiomas operated in France is about 4.2 per 100,000 person/year. To our knowledge, this work is the most important study evaluating the different subtypes of meningiomas and it validates the relevance of histological databases for cen...
Brunon, J
Published in
Neuro-Chirurgie
To treat or not to treat an asymptomatic or pauci-symptomatic benign meningioma, that is the question. And if treatment is necessary, what is the best technique: radical resection, sub-total resection or radiotherapy? This question is also pertinent for meningiomas of the skull base, posterior part of the sagittal sinus, anterior part of the forame...
Biau, J Khalil, T Verrelle, P Lemaire, J-J
Published in
Neuro-Chirurgie
This review focuses on the role of radiosurgery and fractionated radiotherapy in the management of intracranial meningiomas, which are the most common benign intracranial tumors. Whenever feasible, surgery remains a cornerstone of treatment in effective health care treatment where modern radiotherapy plays an important role. Irradiation can be prop...
Peyre, M Kalamarides, M
Published in
Neuro-Chirurgie
New advances have recently been made in the field of molecular genetics and mouse modeling of meningiomas, opening new perspectives for future treatments. Recent genome-wide genotyping and exome sequencing studies have confirmed the pivotal role of NF2 in meningioma tumorigenesis, concerning roughly half of the tumors, and unraveled new mutations i...
Baldi, I Engelhardt, J Bonnet, C Bauchet, L Berteaud, E Grüber, A Loiseau, H
Published in
Neuro-Chirurgie
Although they represent about a third of all the tumors of the central nervous system, knowledge concerning meningioma epidemiology (including incidence data and exploration of the risk factors) remains scarce compared to that of gliomas. A limited number of cancer registries worldwide only record malignant brain tumors, however their completeness ...
Zanello, M Wager, M Corns, R Capelle, L Mandonnet, E Fontaine, D Reyns, N Dezamis, E Matsuda, R Bresson, D
...
Published in
Neuro-Chirurgie
Functional-based surgical resection aids the safe and complete resection of cavernous angiomas located in eloquent areas while minimizing the surgical risks. Functional mapping has to be considered in such challenging cases.
Mandonnet, E
Published in
Neuro-Chirurgie
Mastering the language map and its dynamical properties should be a basic prerequisite for any neurosurgeon who wishes to operate on the brain with the aim of optimizing the extent of resection while preserving language abilities.
Chenin, L Lefranc, M Velut, S Foulon, P Havet, E Peltier, J
Published in
Neuro-Chirurgie
Knowledge of the encephalon anatomy is crucial for neurosurgical practice, especially the main cortical functional structures and their connections. General organisation of the encephalon is presented with frontal, parietal, occipital, temporal, limbic and insular lobes and their Brodmann correspondence. Secondly, subcortical anatomy will be presen...
Pallud, J Mandonnet, E Corns, R Dezamis, E Parraga, E Zanello, M Spena, G
Published in
Neuro-Chirurgie
Direct electrical stimulation is an easy, accurate, reliable and safe invasive technique for the intraoperative detection of both cortical and subcortical functional brain connectivity for clinical purpose. In our opinion, it is the optimal technique for minimizing the risk of neurological sequelae when resecting in eloquent brain areas.
Mellerio, C Charron, S Lion, S Roca, P Kuchcinski, G Legrand, L Edjlali, M Naggara, O Meder, J-F Pallud, J
...
Published in
Neuro-Chirurgie
Surgical resection of gliomas involving eloquent brain areas must be maximal in order to improve patients' survival, and safe to prevent postoperative impairments. Therefore, the precise spatial relationship between the lesion and eloquent brain areas needs to be established. Functional magnetic resonance imaging and diffusion tensor imaging are ro...
