Yang, Ze-Yong Zhou, Lei Meng, Qiong Shi, Hong Li, Yuan-Hai
Published in
Neural regeneration research
Autophagy plays essential roles in cell survival. However, the functions and regulation of the autophagy-related proteins Atg5, LC3B, and Beclin 1 during anesthetic-induced developmental neurotoxicity remain unclear. This study aimed to understand the autophagy pathways and mechanisms that affect neurotoxicity, induced by the anesthetic emulsified ...
Iavorovschi, Alexandra M Wang, Aijun
Published in
Neural regeneration research
Tang, Yun-Liang Fang, Long-Jun Zhong, Ling-Yang Jiang, Jian Dong, Xiao-Yang Feng, Zhen
Published in
Neural regeneration research
The exact mechanisms associated with secondary brain damage following traumatic brain injury (TBI) remain unclear; therefore, identifying the critical molecular mechanisms involved in TBI is essential. The mRNA expression microarray GSE2871 was downloaded from the Gene Expression Omnibus (GEO) repository. GSE2871 comprises a total of 31 cerebral co...
Han, Qi Xu, Xiao-Ming
Published in
Neural regeneration research
Sumbria, Rachita K
Published in
Neural regeneration research
Liu, Ai-Mei Chen, Bo-Li Yu, Ling-Tai Liu, Tao Shi, Ling-Ling Yu, Pan-Pan Qu, Yi-Bo So, Kwok-Fai Zhou, Li-Bing
Published in
Neural regeneration research
Multiple types of stem cells have been proposed for the treatment of spinal cord injury, but their comparative information remains elusive. In this study, a rat model of T10 contusion spinal cord injury was established by the impactor method. Human umbilical cord-derived mesenchymal stem cells (UCMSCs) or human adipose tissue-derived mesenchymal st...
Liu, Na Zhang, Xiao-Lu Jiang, Shu-Yuan Shi, Jing-Hua Cui, Jun-He Liu, Xiao-Lei Han, Li-Hong Gong, Ke-Rui Yan, Shao-Chun Xie, Wei
...
Published in
Neural regeneration research
Hypoxic preconditioning has been shown to improve hypoxic tolerance in mice, accompanied by the downregulation of DNA methyltransferases (DNMTs) in the brain. However, the roles played by DNMTs in the multiple neuroprotective mechanisms associated with hypoxic preconditioning remain poorly understood. This study aimed to establish an in vitro model...
Caminati, Gabriella Procacci, Piero
Published in
Neural regeneration research
Intrinsically disordered proteins, such as tau or α-synuclein, have long been associated with a dysfunctional role in neurodegenerative diseases. In Alzheimer's and Parkinson's' diseases, these proteins, sharing a common chemical-physical pattern with alternating hydrophobic and hydrophilic domains rich in prolines, abnormally aggregate in tangles ...
Mitrofanis, John Henderson, Luke A
Published in
Neural regeneration research
Doxtater, Kyle Tripathi, Manish K Khan, Mohammad Moshahid
Published in
Neural regeneration research