Sigma-1 receptor: culprit and rescuer in motor neuron diseases
Published in Neural Regeneration Research
An appropriate level of autophagy reduces emulsified isoflurane-induced apoptosis in fetal neural stem cells.
Published in Neural regeneration research
Autophagy plays essential roles in cell survival. However, the functions and regulation of the autophagy-related proteins Atg5, LC3B, and Beclin 1 during anesthetic-induced developmental neurotoxicity remain unclear. This study aimed to understand the autophagy pathways and mechanisms that affect neurotoxicity, induced by the anesthetic emulsified ...
Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validation.
Published in Neural regeneration research
The exact mechanisms associated with secondary brain damage following traumatic brain injury (TBI) remain unclear; therefore, identifying the critical molecular mechanisms involved in TBI is essential. The mRNA expression microarray GSE2871 was downloaded from the Gene Expression Omnibus (GEO) repository. GSE2871 comprises a total of 31 cerebral co...
Engineering mesenchymal stromal/stem cell-derived extracellular vesicles with improved targeting and therapeutic efficie...
Published in Neural regeneration research
Neurotrophin-3-mediated locomotor recovery: a novel therapeutic strategy targeting lumbar neural circuitry after spinal ...
Published in Neural regeneration research
Targeting the transferrin receptor to develop erythropoietin for Alzheimer's disease.
Published in Neural regeneration research
Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic precondition...
...Published in Neural regeneration research
Hypoxic preconditioning has been shown to improve hypoxic tolerance in mice, accompanied by the downregulation of DNA methyltransferases (DNMTs) in the brain. However, the roles played by DNMTs in the multiple neuroprotective mechanisms associated with hypoxic preconditioning remain poorly understood. This study aimed to establish an in vitro model...
Human adipose tissue- and umbilical cord-derived stem cells: which is a better alternative to treat spinal cord injury?
Published in Neural regeneration research
Multiple types of stem cells have been proposed for the treatment of spinal cord injury, but their comparative information remains elusive. In this study, a rat model of T10 contusion spinal cord injury was established by the impactor method. Human umbilical cord-derived mesenchymal stem cells (UCMSCs) or human adipose tissue-derived mesenchymal st...
Mounting evidence of FKBP12 implication in neurodegeneration.
Published in Neural regeneration research
Intrinsically disordered proteins, such as tau or α-synuclein, have long been associated with a dysfunctional role in neurodegenerative diseases. In Alzheimer's and Parkinson's' diseases, these proteins, sharing a common chemical-physical pattern with alternating hydrophobic and hydrophilic domains rich in prolines, abnormally aggregate in tangles ...
How and why does photobiomodulation change brain activity?
Published in Neural regeneration research
