Published in Network Neuroscience
Increased study and methodological innovation have led to growth in the field of fetal brain fMRI. An important gap yet to be addressed is optimization of fetal fMRI preprocessing. Rapid developmental changes, imaged within the maternal compartment using an abdominal coil, introduce novel constraints that challenge established methods used in adult...
Published in Network Neuroscience
Graph-theoretical methods have been widely used to study human brain networks in psychiatric disorders. However, the focus has primarily been on global graphic metrics with little attention to the information contained in paths connecting brain regions. Details of disruption of these paths may be highly informative for understanding disease mechani...
Published in Network Neuroscience
Modern neuroimaging promises to transform how we understand human brain function, as well as how we diagnose and treat mental disorders. However, this promise hinges on the development of computational tools for distilling complex, high-dimensional neuroimaging data into simple representations that can be explored in research or clinical settings. ...
Published in Network Neuroscience
The dynamic repertoire of functional brain networks is constrained by the underlying topology of structural connections. Despite this intrinsic relationship between structural connectivity (SC) and functional connectivity (FC), integrative and multimodal approaches to combine the two remain limited. Here, we propose a new adaptive filter for estima...
Published in Network Neuroscience
The initial promise of resting-state fMRI was that it would reflect “intrinsic” functional relationships in the brain free from any specific task context, yet this assumption has remained untested until recently. Here we propose a latent variable method for estimating intrinsic functional connectivity (FC) as an alternative to rest FC. We show that...
Published in Network Neuroscience
Cognitive impairment in multiple sclerosis (MS) is common and relates to structural and functional connectivity. However, it remains unclear whether the interplay (coupling) between structural and functional connectivity could be a biomarker of MS-related cognitive impairment. This study investigated the cognitive relevance of structure-function co...
Published in Network Neuroscience
Neural activity coordinated across different scales from neuronal circuits to large-scale brain networks gives rise to complex cognitive functions. Bridging the gap between micro- and macroscale processes, we present a novel framework based on the maximum entropy model to infer a hybrid resting-state structural connectome, representing functional i...
Published in Network Neuroscience
Epilepsy is increasingly recognized as a network disorder characterized by recurrent seizures as well as broad-ranging cognitive difficulties and affective dysfunction. Our manuscript reviews recent literature highlighting brain network substrates of cognitive and affective dysfunction in common epilepsy syndromes, namely temporal lobe epilepsy sec...
Published in Network Neuroscience
Many studies of brain networks have revealed densely connected regions forming the rich club and diverse club, which occupy the central position of the hierarchical brain system. Here, we explore the hierarchical topology in Parkinson’s disease (PD) and investigate the neural effect of levodopa on it. We show that within the core position of the hi...
Published in Network Neuroscience
In recent years, a growing body of studies have aimed at analyzing the brain as a complex dynamic system by using various neuroimaging data. This has opened new avenues to answer compelling questions about the brain function in health and disease. However, methods that allow for providing statistical inference about how the complex interactions of ...
