van Schijndel, M A Jansen, L A W Caarls, P J van 't Veer, F Wierdsma, A I van Wijngaarden, J D H van Waarde, J A van Busschbach, J J
Published in
Nederlands tijdschrift voor geneeskunde
MPUs are unevenly distributed across the country; care content is adequate, but education, tighter multidisciplinary cooperation and availability of somatic nursing expertise on every shift could improve care on MPUs. The departments should also pay more attention to care chain arrangements. The field standards are too stringent; these could be imp...
Cohen, A F
Published in
Nederlands tijdschrift voor geneeskunde
Recently, it was shown that more than 40% of the clinical drug trials in the Netherlands does not reach the stage of publication. Although the non-publication rate of clinical trials seems to have improved compared to previous studies, it is still far from optimal, in particular among phase I trials. In this article the life cycle of clinical drug ...
Kloppenborg, R P
Published in
Nederlands tijdschrift voor geneeskunde
Due to its higher resolution, MRI in which a magnet with a field strength of 7 Tesla (7T MRI) is used, is able to image smaller abnormalities. 7T MRI is a promising tool for research into the causes of cerebral small vessel disease. Originally this technique was aimed at imaging the small perforating brain vessels and in particular at the micro-thr...
van Seben, R Geerlings, S E Buurman, B M
Published in
Nederlands tijdschrift voor geneeskunde
When patients are transferred from the hospital to other health care settings, responsibility for the patient is transferred from the treating physician, nurse, paramedic or pharmacist at the hospital to the next health care provider. Good patient handovers from hospital to other healthcare settings are essential to ensure continuity of care. Howev...
Goveart, J A van Dijk, W A Wouters, M W J M
Published in
Nederlands tijdschrift voor geneeskunde
We have recently shown that costs of surgical treatment for colorectal carcinoma differ greatly between various patient groups in the Netherlands. Those cost-differences could mostly be explained by the fact that high-risk patients have a greater risk of complications, which generate higher hospital costs. Hospitals with a high-risk population, for...
IJsselstijn, L van Houten, A A Weerkamp, F
Published in
Nederlands tijdschrift voor geneeskunde
Interpretation of laboratory parameters in cases of haemochromatosis can be difficult. Here, we describe two patients with markedly elevated transferrin saturation and high ferritin levels. The first patient is a 51-year-old woman who had been complaining of fatigue, abdominal pain and arthritis for three years. Her liver enzymes were mildly elevat...
Roemeling, S Gansevoort, R T Berger, M Y de Jong, I J
Published in
Nederlands tijdschrift voor geneeskunde
Asymptomatic microscopic haematuria is a common finding and can have many different causes. Only a small fraction of patients referred for microscopic haematuria have an underlying urological malignancy or serious nephrogenic disease. It is important that only those patients with microscopically confirmed microscopic haematuria are referred. Often ...
Numan, T van den Boogaard, M Kampen, A M Rood, P J T Peelen, L M Slooter, A J C
Published in
Nederlands tijdschrift voor geneeskunde
There was considerable disagreement between the classifications of individual delirium experts, based on exactly the same information, indicating the difficulty of the diagnosis. Furthermore, the sensitivity of the delirium screening tools used by the clinical nurses was poor. Further research should focus on the development of objective methods fo...
Burger, D M
Published in
Nederlands tijdschrift voor geneeskunde
- In a previous issue, a case report was presented in the Dutch Journal of Medicine (NTvG) of a patient who had variable clozapine levels after switching from regular cigarettes to an e-cigarette and vice versa.- Besides clozapine there are a number of other agents with a narrow therapeutic range where pharmacokinetics can be influenced by smoking....
de Boer, M P Nicia, S Kolff, Q
Published in
Nederlands tijdschrift voor geneeskunde
A 71-year-old man was admitted to the emergency room after high-energy trauma. He suddenly deteriorated several hours after an epidural providing local anaesthetics. At that time, his blood was black and the methaemoglobin level was 69 percent. After administration of methylene blue, he made a full clinical and biochemical recovery.
