Perturbing autism risk genes
Published in Nature Genetics
X-linked inflammatory syndrome
Published in Nature Genetics
Cancer exceptional responders
Published in Nature Genetics
Adaptation to nitrogen
Published in Nature Genetics
Chromothripsis and drug resistance
Published in Nature Genetics
A quantitative genomics map of rice provides genetic insights and guides breeding
...Published in Nature Genetics
A comprehensive rice quantitative trait nucleotide map provides new genetic insights and serves as the basis for RiceNavi, a tool to optimize breeding schemes.
Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells
...Published in Nature Genetics
DIS3 deficiency alters CTCF and cohesin binding at the Igh locus in B cells. These cells show decreased class-switch recombination but increased chromosomal translocations.
Metabolic control of DNA methylation in naive pluripotent cells
...Published in Nature Genetics
Stat3 depletion in pluripotent cells decreases α-ketoglutarate and increases the expression of Otx2 and its targets Dnmt3a and Dnmt3b, leading to global DNA hypermethylation.
Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Pro...
...Published in Nature Genetics
Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in individuals of European and African ancestry provide insights into its relationship with anxiety and depressive disorders and identify potential candidates for drug repositioning.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease patho...
...Published in Nature Genetics
Integrating human brain proteomes with genome-wide association data followed by Mendelian randomization identifies 11 genes with potentially causal roles in Alzheimer’s disease pathogenesis.
