Liao, Chun-Ming Kuo, Wei-Yin Kung, Pei-Tseng Chuan, Chuang-Hui Tsai, Wen-Chen
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Multiple sclerosis (Houndmills, Basingstoke, England)
The increasing trend in the prevalence of multiple sclerosis (MS) cannot be neglected. Long-term epidemiological investigations of MS patients who have been registered in Taiwan are very scarce. The aim of this study was to investigate the epidemiology of MS and medical utilisation among MS patients in Taiwan. The National Health Insurance Research...
Leekoff, Mark Culpepper, William Jin, Shan Lee-Wilk, Terry Wallin, Mitchell
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Multiple sclerosis (Houndmills, Basingstoke, England)
Very little is known regarding the impact of post traumatic stress disorder (PTSD) on the course of multiple sclerosis (MS). To explore the impact of pre-existing PTSD on MS relapses, magnetic resonance imaging (MRI) activity, and disability in a large population-based cohort. Military Veterans with MS and PTSD prior to symptom onset (MSPTSD, n = 9...
Sarkar, Pamela Redondo, Juliana Hares, Kelly Bailey, Steven Georgievskaya, Anastasia Heesom, Kate Kemp, Kevin C Scolding, Neil J Rice, Claire M
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Multiple sclerosis (Houndmills, Basingstoke, England)
Cell-based therapies for multiple sclerosis (MS), including those employing autologous bone marrow-derived mesenchymal stromal cells (MSC) are being examined in clinical trials. However, recent studies have identified abnormalities in the MS bone marrow microenvironment. We aimed to compare the secretome of MSC isolated from control subjects (C-MSC...
Manuel Escobar, Juan Cortese, Marianna Edan, Gilles Freedman, Mark S Hartung, Hans-Peter Montalbán, Xavier Sandbrink, Rupert Radü, E-W Barkhof, Frederik Wicklein, Eva-Maria
...
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Multiple sclerosis (Houndmills, Basingstoke, England)
There is a lack of studies on the association between obesity and conversion from a clinically isolated syndrome (CIS) to multiple sclerosis (MS). The aim of this study was to determine whether obesity predicts disease activity and prognosis in patients with CIS. Body mass index (BMI) at baseline was available for 464 patients with CIS in BENEFIT. ...
Kever, Anne Riley, Claire S Leavitt, Victoria M
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Multiple sclerosis (Houndmills, Basingstoke, England)
Persons with multiple sclerosis (pwMS) frequently conceal their diagnosis, fearing professional and personal repercussions of disclosing. Associations of concealment behavior and expected consequences of disclosure with psychosocial outcomes were examined in 90 pwMS who completed validated self-report measures of diagnosis concealment, loneliness, ...
Misicka, Elina Davis, Mary F Kim, Woori Brugger, Steven W Beales, Jeremy Loomis, Stephanie Bronson, Paola G Briggs, Farren Bs
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Multiple sclerosis (Houndmills, Basingstoke, England)
Age at onset of multiple sclerosis (MS) is an objective, influential predictor of the evolution of MS independent of disease duration. Determine the influence of MS genetic predisposition on age of onset. We conducted a comprehensive investigation of MS risk variants and age at onset in 3495 non-Latinx white individuals, including for combinations ...
Andersen, Johanna Balslev Wandall-Holm, Malthe Faurschou Andersen, Per Kragh Sellebjerg, Finn Magyari, Melinda
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Multiple sclerosis (Houndmills, Basingstoke, England)
Pregnancy is considered to influence the disease course in women with multiple sclerosis (MS). The aim of this study was to investigate the effect of pregnancy on long-term disability accrual in women with MS. The Danish Multiple Sclerosis Registry (DMSR) was used to identify women diagnosed with clinically isolated syndrome or relapsing-remitting ...
Lozinski, Brian M Yong, V Wee
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Multiple sclerosis (Houndmills, Basingstoke, England)
While people with multiple sclerosis (PwMS) historically were advised to avoid physical activity to reduce symptoms such as fatigue, they are now encouraged to remain active and to enlist in programs of exercise. However, despite an extensive current literature that exercise not only increases physical well-being but also their cognition and mental...
O'Mahony, Julia Banwell, Brenda Laporte, Audrey Brown, Adalsteinn Bolongaita, Lady Bar-Or, Amit Yeh, E Ann Marrie, Ruth Ann
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Multiple sclerosis (Houndmills, Basingstoke, England)
We previously found that children with the chronic disease multiple sclerosis (MS) reported lower health-related quality of life (HRQoL) when compared to children who experienced the transient illness termed monophasic acquired demyelinating syndromes (monoADS). Parents of children with MS also reported lower HRQoL. We evaluated whether parental HR...
Solomon, Andrew J Kaisey, Marwa Krieger, Stephen C Chahin, Salim Naismith, Robert T Weinstein, Sarah M Shinohara, Russell T Weinshenker, Brian G
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Multiple sclerosis (Houndmills, Basingstoke, England)
Few studies have addressed the results of educational efforts concerning proper use of McDonald criteria (MC) revisions outside multiple sclerosis (MS) subspecialty centers. Neurology residents and MS subspecialist neurologists demonstrated knowledge gaps for core elements of the MC in a recent prior study. To assess comprehension and application o...