Correction to: Role of Th22 cells in Helicobacter pylori‑related gastritis and peptic ulcer diseases.
Published in Molecular biology reports
Correction to: Role of Th22 cells in Helicobacter pylori‑related gastritis and peptic ulcer diseases.
Correction to: A systematic review on the role of MSC‑derived exosomal miRNAs in the treatment of heart failure.
Published in Molecular biology reports
Heart failure (HF) is a deeply serious clinical problem that remains unsolved. Many reports highlight the cardioprotective properties of mesenchymal stem cells (MSCs), the factors contained in their secretome being particularly important for this function; these include the exosomal miRNAs (exo-miRNAs) secreted with or without stimulus which can mo...
Multiple roles of m6A methylation in epithelial-mesenchymal transition.
Published in Molecular biology reports
Epithelial-mesenchymal transition (EMT) plays an important role in migration and invasion of cancer cell and the development of tissue fibrosis diseases. N6-methyladenosine (m6A) is the most extensive type of RNA methylation and has aroused extensive interest in recent years. However, m6A methylation seems to play different roles in different cance...
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation.
...Published in Molecular biology reports
As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, we know that the STAT family consists of several transcription factors which regulate various molecular and cellular processes,...
Review on NAD(P)H dehydrogenase quinone 1 (NQO1) pathway.
Published in Molecular biology reports
NQO1 is an enzyme present in humans which is encoded by NQO1 gene. It is a protective antioxidant agent, versatile cytoprotective agent and regulates the oxidative stresses of chromatin binding proteins for DNA damage in cancer cells. The oxidization of cellular pyridine nucleotides causes structural alterations to NQO1 and changes in its capacity ...
CRISPR-Cas9 based stress tolerance: New hope for abiotic stress tolerance in chickpea (Cicer arietinum).
...Published in Molecular biology reports
Plants are subjected to biotic and abiotic stresses regularly, which irreparably harm agricultural production. Eco-friendly and sustainable technology to deal with this challenge is to breed abiotic stress tolerant cultivars. To generate crop plants conferring resistance against stresses, conventional breeding was used in the past, but because of t...
Milk fat-globule epidermal growth factor 8: A potential Regulator of Cutaneous Wound Healing.
Published in Molecular biology reports
Destroying the integrity of the skin may causes disability and even death from injury or illness. Wound healing is a core mechanism to maintain skin barrier function. Milk fat-globule epidermal growth factor 8 (MFG-E8) is a key factor in wound healing and is involved in regulating blood coagulation, mediating macrophage uptake of apoptotic cells, s...
Anti-Microbial Peptides: Strategies of Design and Development and Their Promising Wound-Healing Activities.
Published in Molecular biology reports
Current approaches used to overcome microbial infections are becoming inefficient due to the overuse or misuse of antibiotics. Antimicrobial peptides (AMPs) are one of the most promising substitutional candidates for commercial antibiotics. The publications in the field of in silico design of AMPs with focus on the wound-healing AMPs were searched ...
A systematic review on the role of MSC-derived exosomal miRNAs in the treatment of heart failure.
Published in Molecular biology reports
Heart failure (HF) is a deeply serious clinical problem that remains unsolved. Many reports highlight the cardioprotective properties of mesenchymal stem cells (MSCs), the factors contained in their secretome being particularly important for this function; these include the exosomal miRNAs (exo-miRNAs) secreted with or without stimulus which can mo...
Vitamin D and cardiovascular disease risk. A literature overview.
Published in Molecular biology reports
Atherosclerosis and cerebro and cardiovascular disease associated represent the major cause of morbidity and mortality worldwide. Recently, vitamin D deficiency has been considered a new potential risk factor of these conditions. In this reviw we briefly describe the biological role of vitamin D, analyze the pathophysiological associations between ...
