Sudhakar, Manu Winfred, Sofi Beaula Meiyazhagan, Gowri Venkatachalam, Deepa Parvathy
Published in
Molecular and Cellular Biochemistry
A growing amount of epidemiological data from multiple countries indicate an increased prevalence of obesity, more importantly central obesity, among hospitalized subjects with COVID-19. This suggests that obesity is a major factor contributing to adverse outcome of the disease. As it is a metabolic disorder with dysregulated immune and endocrine f...
Davis, Gavin Li, Kin Thankam, Finosh G. Wilson, Daniel R. Agrawal, Devendra K.
Published in
Molecular and Cellular Biochemistry
Since the initial outbreak of coronavirus disease 2019 (COVID-19), extensive research has emerged from across the globe to understand the pathophysiology of this novel coronavirus. Transmission of this virus is a subject of particular interest as researchers work to understand which protective and preventative measures are most effective. Despite t...
Hasslocher-Moreno, Alejandro Marcel
Published in
Molecular and Cellular Biochemistry
Rommasi, Foad Nasiri, Mohammad Javad Mirsaeidi, Mehdi
Published in
Molecular and Cellular Biochemistry
The novel coronavirus pandemic has emerged as one of the significant medical-health challenges of the current century. The World Health Organization has named this new virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first detection of SARS-CoV-2 in November 2019 in Wuhan, China, physicians, researchers, and others have...
Chamardani, Tahmineh Mohammadi Amiritavassoli, Samaneh
Published in
Molecular and Cellular Biochemistry
Active neutrophils participate in innate and adaptive immune responses through various mechanisms, one of the most important of which is the formation and release of neutrophil extracellular traps (NETs). The NETs are composed of network-like structures made of histone proteins, DNA and other released antibacterial proteins by activated neutrophils...
Tarique, Mohammed Ahmad, Shaban Malik, Arshi Ahmad, Irfan Saeed, Mohd Almatroudi, Ahmad Qadah, Talal Murad, Manal Abdulaziz Mashraqi, Mutaib Alam, Qamre
...
Published in
Molecular and Cellular Biochemistry
Molnár, Miklós Horváth, Katalin Dankó, Tamás Somlyai, Ildikó Kovács, Beáta Zs Somlyai, Gábor
Published in
Molecular and cellular biochemistry
Deuterium (D) is a stable isotope of hydrogen (H) with a mass number of 2. It is present in natural waters in the form of HDO, at a concentration of 16.8 mmol/L, equivalent to 150 ppm. In a phase II clinical study, deuterium depletion reduced fasting glucose concentration and insulin resistance. In this study, we tested the effect of subnormal D-co...
Li, Y Robert Zhu, Hong
Published in
Molecular and cellular biochemistry
Vitamin C, also known as ascorbic acid or ascorbate, is a water-soluble vitamin synthesized in plants as well as in animals except humans and several other animal species. Humans obtain vitamin C from dietary sources and via vitamin supplementation. Vitamin C possesses important biological functions, including serving as a cofactor for many enzymes...
Singh, Aishwarya Gupta, Nidhi Khandakar, Hena Kaushal, Seema Seth, Amlesh Pandey, R. M. Sharma, Alpana
Published in
Molecular and Cellular Biochemistry
Urothelial carcinoma of bladder (UBC), a highly prevalent urological malignancy associated with high mortality and recurrence rate. Standard diagnostic method currently being used is cystoscopy but its invasive nature and low sensitivity stresses for identifying predictive diagnostic marker. Autophagy, a cellular homeostasis maintaining process, is...
Alber, Jana Föller, Michael
Published in
Molecular and cellular biochemistry
Endocrine and paracrine fibroblast growth factor 23 (FGF23) is a protein predominantly produced by bone cells with strong impact on phosphate and vitamin D metabolism by targeting the kidney. Plasma FGF23 concentration early rises in kidney and cardiovascular diseases correlating with progression and outcome. Lactic acid is generated in anaerobic g...