Corrigendum to: Recurrent Collection of Drosophila melanogaster from Wild African Environments and Genomic Insights into...
Published in Molecular Biology and Evolution
Corrigendum to: IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era
Published in Molecular Biology and Evolution
Corrigendum to: Family-joining: A fast distance-based method for constructing generally labeled trees
Published in Molecular Biology and Evolution
Erratum to: Epimutations in Developmental Genes Underlie the Onset of Domestication in Farmed European Sea Bass
Published in Molecular Biology and Evolution
The Evolution of Reverse Gyrase Suggests a Nonhyperthermophilic Last Universal Common Ancestor.
Published in Molecular biology and evolution
Reverse gyrase (RG) is the only protein found ubiquitously in hyperthermophilic organisms, but absent from mesophiles. As such, its simple presence or absence allows us to deduce information about the optimal growth temperature of long-extinct organisms, even as far as the last universal common ancestor of extant life (LUCA). The growth environment...
Accurate Tracking of the Mutational Landscape of Diploid Hybrid Genomes
Published in Molecular Biology and Evolution
Mutations, recombinations, and genome duplications may promote genetic diversity and trigger evolutionary processes. However, quantifying these events in diploid hybrid genomes is challenging. Here, we present an integrated experimental and computational workflow to accurately track the mutational landscape of yeast diploid hybrids (MuLoYDH) in ter...
EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses
...Published in Molecular Biology and Evolution
High altitude represents some of the most extreme environments worldwide. The genetic changes underlying adaptation to such environments have been recently identified in multiple animals but remain unknown in horses. Here, we sequence the complete genome of 138 domestic horses encompassing a whole altitudinal range across China to uncover the genet...
Disappearance of Icelandic Walruses Coincided with Norse Settlement
Published in Molecular Biology and Evolution
There is a growing body of evidence demonstrating the impacts of human arrival in new “pristine” environments, including terrestrial habitat alterations and species extinctions. However, the effects of marine resource utilization prior to industrialized whaling, sealing, and fishing have largely remained understudied. The expansion of the Norse acr...
Comparative Genomic Characterization of the Multimammate Mouse Mastomys coucha
Published in Molecular Biology and Evolution
Mastomys are the most widespread African rodent and carriers of various diseases such as the plague or Lassa virus. In addition, mastomys have rapidly gained a large number of mammary glands. Here, we generated a genome, variome, and transcriptomes for Mastomys coucha . As mastomys diverged at similar times from mouse and rat, we demonstrate their ...
Opposing Pressures of Speed and Efficiency Guide the Evolution of Molecular Machines
Published in Molecular Biology and Evolution
Many biomolecular machines need to be both fast and efficient. How has evolution optimized these machines along the tradeoff between speed and efficiency? We explore this question using optimizable dynamical models along coordinates that are plausible evolutionary degrees of freedom. Data on 11 motors and ion pumps are consistent with the hypothesi...
