Gao, Bo Wang, Yali Diaby, Mohamed Zong, Wencheng Shen, Dan Wang, Saisai Chen, Cai Wang, Xiaoyan Song, Chengyi
Published in
Mobile DNA
BackgroundTc1/mariner and Zator, as two superfamilies of IS630-Tc1-mariner (ITm) group, have been well-defined. However, the molecular evolution and domestication of pogo transposons, once designated as an important family of the Tc1/mariner superfamily, are still poorly understood.ResultsHere, phylogenetic analysis show that pogo transposases, tog...
Fayad, Nancy Kallassy Awad, Mireille Mahillon, Jacques
Published in
Mobile DNA
Insertion sequences (IS) are ubiquitous transposable elements with a very simple organization: two inverted repeats flanking a transposase coding gene. IS982 is one of 26 insertion sequence families known so far. With 70 registered members in the ISFinder database, this family remains somewhat unexplored, despite the association of many of its memb...
Mérel, Vincent Boulesteix, Matthieu Fablet, Marie Vieira, Cristina
Published in
Mobile DNA
Drosophila has been studied as a biological model for many years and many discoveries in biology rely on this species. Research on transposable elements (TEs) is not an exception. Drosophila has contributed significantly to our knowledge on the mechanisms of transposition and their regulation, but above all, it was one of the first organisms on whi...
Mason, Andrew S. Lund, Ashlee R. Hocking, Paul M. Fulton, Janet E. Burt, David W.
Published in
Mobile DNA
BackgroundEndogenous retroviruses (ERVs) are the remnants of retroviral infections which can elicit prolonged genomic and immunological stress on their host organism. In chickens, endogenous Avian Leukosis Virus subgroup E (ALVE) expression has been associated with reductions in muscle growth rate and egg production, as well as providing the potent...
Dupeyron, Mathilde Baril, Tobias Bass, Chris Hayward, Alexander
Published in
Mobile DNA
BackgroundTc1/mariner transposons are widespread DNA transposable elements (TEs) that have made important contributions to the evolution of host genomic complexity in metazoans. However, the evolution and diversity of the Tc1/mariner superfamily remains poorly understood. Following recent developments in genome sequencing and the availability of a ...
Belyayev, Alexander Josefiová, Jiřina Jandová, Michaela Mahelka, Václav Krak, Karol Mandák, Bohumil
Published in
Mobile DNA
Extensive and complex links exist between transposable elements (TEs) and satellite DNA (satDNA), which are the two largest fractions of eukaryotic genome. These relationships have a crucial effect on genome structure, function and evolution. Here, we report a novel case of mutual relationships between TEs and satDNA. In the genomes of Chenopodium ...
de Albuquerque, Nathalia Rammé Medeiros Ebert, Dieter Haag, Karen Luisa
Published in
Mobile DNA
The extreme genome reduction and physiological simplicity of some microsporidia has been attributed to their intracellular, obligate parasitic lifestyle. Although not all microsporidian genomes are small (size range from about 2 to 50 MB), it is suggested that the size of their genomes has been streamlined by natural selection. We explore the hypot...
Kojima, Kenji K.
Published in
Mobile DNA
BackgroundShort interspersed elements (SINEs) are ubiquitous components of eukaryotic genomes. SINEs are composite transposable elements that are mobilized by non-long terminal repeat (non-LTR) retrotransposons, also called long interspersed elements (LINEs). The 3′ part of SINEs usually originated from that of counterpart non-LTR retrotransposons....
Martin, Eliza C. Vicari, Célia Tsakou-Ngouafo, Louis Pontarotti, Pierre Petrescu, Andrei J. Schatz, David G.
Published in
Mobile DNA
BackgroundV(D) J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The RAG1 and RAG2 genes are thought to have evolved from a RAGL (RAG-like) transposon containing convergently-oriented RAG1-like (RAG1L) and RAG2-like (RAG2L) genes. Elements resembling this presumptive evolutionary...
Maxwell, Patrick H.
Published in
Mobile DNA
Genomics and other large-scale analyses have drawn increasing attention to the potential impacts of transposable elements (TEs) on their host genomes. However, it remains challenging to transition from identifying potential roles to clearly demonstrating the level of impact TEs have on genome evolution and possible functions that they contribute to...
