Storer, Jessica Hubley, Robert Rosen, Jeb Wheeler, Travis J. Smit, Arian F.
Published in
Mobile DNA
Dfam is an open access database of repetitive DNA families, sequence models, and genome annotations. The 3.0–3.3 releases of Dfam (https://dfam.org) represent an evolution from a proof-of-principle collection of transposable element families in model organisms into a community resource for a broad range of species, and for both curated and uncurate...
Etchegaray, Ema Naville, Magali Volff, Jean-Nicolas Haftek-Terreau, Zofia
Published in
Mobile DNA
Transposable elements (TEs) are major components of all vertebrate genomes that can cause deleterious insertions and genomic instability. However, depending on the specific genomic context of their insertion site, TE sequences can sometimes get positively selected, leading to what are called “exaptation” events. TE sequence exaptation constitutes a...
Komkov, Alexander Y. Urazbakhtin, Shamil Z. Saliutina, Maria V. Komech, Ekaterina A. Shelygin, Yuri A. Nugmanov, Gaiaz A. Shubin, Vitaliy P. Smirnova, Anastasia O. Bobrov, Mikhail Y. Tsukanov, Alexey S.
...
Published in
Mobile DNA
BackgroundRetroelements (REs) occupy a significant part of all eukaryotic genomes including humans. The majority of retroelements in the human genome are inactive and unable to retrotranspose. Dozens of active copies are repressed in most normal tissues by various cellular mechanisms. These copies can become active in normal germline and brain tiss...
Gao, Bo Zong, Wencheng Miskey, Csaba Ullah, Numan Diaby, Mohamed Chen, Cai Wang, Xiaoyan Ivics, Zoltán Song, Chengyi
Published in
Mobile DNA
BackgroundA family of Tc1/mariner transposons with a characteristic DD38E triad of catalytic amino acid residues, named Intruder (IT), was previously discovered in sturgeon genomes, but their evolutionary landscapes remain largely unknown.ResultsHere, we comprehensively investigated the evolutionary profiles of ITs, and evaluated their cut-and-past...
Mérel, Vincent Boulesteix, Matthieu Fablet, Marie Vieira, Cristina
Published in
Mobile DNA
Drosophila has been studied as a biological model for many years and many discoveries in biology rely on this species. Research on transposable elements (TEs) is not an exception. Drosophila has contributed significantly to our knowledge on the mechanisms of transposition and their regulation, but above all, it was one of the first organisms on whi...
Quesneville, Hadi
Published in
Mobile DNA
Transposable elements (TEs) are mobile repetitive DNA sequences shown to be major drivers of genome evolution. As the first plant to have its genome sequenced and analyzed at the genomic scale, Arabidopsis thaliana has largely contributed to our TE knowledge. The present report describes 20 years of accumulated TE knowledge gained through the study...
Tatkiewicz, Witold Dickie, James Bedford, Franchesca Jones, Alexander Atkin, Mark Kiernan, Michele Maze, Emmanuel Atangana Agit, Bora Farnham, Garry Kanapin, Alexander
...
Published in
Mobile DNA
An amendment to this paper has been published and can be accessed via the original article.
Henrich, Birgit Hammerlage, Stephanie Scharf, Sebastian Haberhausen, Diana Fürnkranz, Ursula Köhrer, Karl Peitzmann, Lena Fiori, Pier Luigi Spergser, Joachim Pfeffer, Klaus
...
Published in
Mobile DNA
BackgroundMobile genetic elements are found in genomes throughout the microbial world, mediating genome plasticity and important prokaryotic phenotypes. Even the cell wall-less mycoplasmas, which are known to harbour a minimal set of genes, seem to accumulate mobile genetic elements. In Mycoplasma hominis, a facultative pathogen of the human urogen...
Ueda, Mahoko Takahashi Kryukov, Kirill Mitsuhashi, Satomi Mitsuhashi, Hiroaki Imanishi, Tadashi Nakagawa, So
Published in
Mobile DNA
BackgroundEndogenous retroviruses (ERVs) are remnants of ancient retroviral infections of mammalian germline cells. A large proportion of ERVs lose their open reading frames (ORFs), while others retain them and become exapted by the host species. However, it remains unclear what proportion of ERVs possess ORFs (ERV-ORFs), become transcribed, and se...
Gao, Bo Wang, Yali Diaby, Mohamed Zong, Wencheng Shen, Dan Wang, Saisai Chen, Cai Wang, Xiaoyan Song, Chengyi
Published in
Mobile DNA
BackgroundTc1/mariner and Zator, as two superfamilies of IS630-Tc1-mariner (ITm) group, have been well-defined. However, the molecular evolution and domestication of pogo transposons, once designated as an important family of the Tc1/mariner superfamily, are still poorly understood.ResultsHere, phylogenetic analysis show that pogo transposases, tog...