The role of surgery in the management of metastatic kidney cancer: an evidence-based collaborative review.
The current manuscript aims to provide an up to date evidence based analysis on the status of surgery in the metastatic renal cell carcinoma setting. It includes the role of surgery in the primary tumor as well as recent perspective on the surgical management of metastatic disease.
HRQoL questionnaires should become a standard method to evaluate medical/surgical outcomes in uro-oncology. Their implementation may significantly improve patients' satisfaction and help physicians in the decision-making process and possibly reduce health care costs.
The current evidence suggests that patients with large and/or complex urolithiasis might benefit from the adjunct of flexible nephroscopy and/or ureteroscopy to rigid PNL.
The effects of ultrafiltration and diuretic therapies on oxidative stress markers in patients with cardio-renal syndrome...
The effects of UF and furosemide therapies were similar on oxidative stress markers in patients with CRS. These methods safely decrease volume overload in a short-term period.
An exploratory analysis of the association between levels of hormones implied in steroid biosynthesis and activity of ab...
This analysis does not suggest a significant association between baseline hormonal values, or changes induced by abiraterone, and treatment activity.
Development and validation of the Italian version of the Intermittent Self-Catheterization Questionnaire.
The Italian ISC-Q has the same psychometric characteristics of the original questionnaire. ISC-Q is a valid, reliable and sensitive patient related outcome, specifically focused on ISC. our work provides a new validated measure for Italian patients to explore in future studies the role and impact of ISC.
Can we predict chemotherapy response in patients with metastatic testicular cancer? Role of thrombocytosis as a novel ma...
Thrombocytosis is seen in 25% of patients with testicular GCT and it is found to be associated with poorer chemotherapy response in metastatic patients. It can be used to predict the response to chemotherapy.
Nocturnal LUTS in older people is the result of a high nocturnal urine production related to NP with a higher nocturnal bladder capacity. The analyses of micturition, incontinence and PVR, and the accurate evaluation of the presence or absence of NP seems to be the key point for a better therapeutic choice in patients suffering by Nocturnal LUTS.
Our findings provide further evidence that the expression of MMP-9 contribute to PCa risk. MMP-9 protein overexpression was found in prostate cancers, low expression in any of the normal tissues or in benign prostatic tissue. MMP-9 is potentially an important prostate tumor marker.