Widder, Stefanie Görzer, Irene Friedel, Benjamin Rahimi, Nina Schwarz, Stefan Jaksch, Peter Knapp, Sylvia Puchhammer-Stöckl, Elisabeth
Published in
Microbiome
The virome of lung transplant recipients (LTRs) under immunosuppressive therapy is dominated by non-pathogenic Anelloviridae and further includes several pathogenic viruses such as Herpesviruses or respiratory viruses. It is unclear whether the donor-derived virome in the transplanted lung influences recipient virome dynamics in other body compartm...
Temerozo, Jairo R Fintelman-Rodrigues, Natalia Dos Santos, Monique Cristina Hottz, Eugenio D Sacramento, Carolina Q de Paula Dias da Silva, Aline Mandacaru, Samuel Coelho Dos Santos Moraes, Emilly Caroline Trugilho, Monique R O Gesto, João S M
...
Published in
Microbiome
Critically ill 2019 coronavirus disease (COVID-19) patients under invasive mechanical ventilation (IMV) are 10 to 40 times more likely to die than the general population. Although progression from mild to severe COVID-19 has been associated with hypoxia, uncontrolled inflammation, and coagulopathy, the mechanisms involved in the progression to seve...
Wolf, Patricia G Cowley, Elise S Breister, Adam Matatov, Sarah Lucio, Luke Polak, Paige Ridlon, Jason M Gaskins, H Rex Anantharaman, Karthik
Published in
Microbiome
Recent evidence implicates microbial sulfidogenesis as a potential trigger of colorectal cancer (CRC), highlighting the need for comprehensive knowledge of sulfur metabolism within the human gut. Microbial sulfidogenesis produces genotoxic hydrogen sulfide (H2S) in the human colon using inorganic (sulfate) and organic (taurine/cysteine/methionine) ...
Li, Pu-Dong Zhu, Zeng-Rong Zhang, Yunzeng Xu, Jianping Wang, Hongkai Wang, Zhengyi Li, Hongye
Published in
Microbiome
Plants can recruit beneficial microbes to enhance their ability to defend against pathogens. However, in contrast to the intensively studied roles of the rhizosphere microbiome in suppressing plant pathogens, the collective community-level change and effect of the phyllosphere microbiome in response to pathogen invasion remains largely elusive. Her...
Gregory, Ann C Gerhardt, Kenji Zhong, Zhi-Ping Bolduc, Benjamin Temperton, Ben Konstantinidis, Konstantinos T Sullivan, Matthew B
Published in
Microbiome
Microbes and their viruses are hidden engines driving Earth's ecosystems from the oceans and soils to humans and bioreactors. Though gene marker approaches can now be complemented by genome-resolved studies of inter-(macrodiversity) and intra-(microdiversity) population variation, analytical tools to do so remain scattered or under-developed. Here,...
Freudenthal, Jule Ju, Feng Bürgmann, Helmut Dumack, Kenneth
Published in
Microbiome
BackgroundDuring wastewater treatment, the wastewater microbiome facilitates the degradation of organic matter, reduction of nutrients, and removal of gut parasites. While the latter function is essential to minimize public health risks, the range of parasites involved and how they are removed is still poorly understood.ResultsUsing shotgun metagen...
Yang, Shengzhi Liu, Yu Yang, Nan Lan, Yue Lan, Weiqi Feng, Jinyi Yue, Bisong He, Miao Zhang, Liang Zhang, Anyun
...
Published in
Microbiome
BackgroundChronic diarrhea is a common disease causing morbidity and mortality of captive rhesus macaques (RMs, Macaca mulatta). Chronic diarrhea in RMs is typically characterized by long-term diarrhea and a weak response to antibiotic treatment. Diarrhea is also a common disease in humans and can cause death. However, the etiology of about half of...
Rudolph, Katja Schneider, Dominik Fichtel, Claudia Daniel, Rolf Heistermann, Michael Kappeler, Peter M.
Published in
Microbiome
BackgroundVarious aspects of sociality can benefit individuals’ health. The host social environment and its relative contributions to the host-microbiome relationship have emerged as key topics in microbial research. Yet, understanding the mechanisms that lead to structural variation in the social microbiome, the collective microbial metacommunity ...
Kuehnast, Torben Abbott, Carmel Pausan, Manuela R. Pearce, David A. Moissl-Eichinger, Christine Mahnert, Alexander
Published in
Microbiome
A human spaceflight to Mars is scheduled for the next decade. In preparation for this unmatched endeavor, a plethora of challenges must be faced prior to the actual journey to Mars. Mission success will depend on the health of its crew and its working capacity. Hence, the journey to Mars will also depend on the microbiome and its far-reaching effec...
Shi, Yushu Zhang, Liangliang Peterson, Christine B. Do, Kim-Anh Jenq, Robert R.
Published in
Microbiome
BackgroundIn microbiome data analysis, unsupervised clustering is often used to identify naturally occurring clusters, which can then be assessed for associations with characteristics of interest. In this work, we systematically compared beta diversity and clustering methods commonly used in microbiome analyses. We applied these to four published d...
