Reverter, Antonio Ballester, Maria Alexandre, Pamela A. Mármol-Sánchez, Emilio Dalmau, Antoni Quintanilla, Raquel Ramayo-Caldas, Yuliaxis
Published in
Microbiome
Background Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic control over the gut microbial communities. In pigs, previous studies are based on classical “single-gene-single-trait” approaches and have evaluated t...
Wylezich, Claudia Calvelage, Sten Schlottau, Kore Ziegler, Ute Pohlmann, Anne Höper, Dirk Beer, Martin
Published in
Microbiome
Background The detection of pathogens in clinical and environmental samples using high-throughput sequencing (HTS) is often hampered by large amounts of background information, which is especially true for viruses with small genomes. Enormous sequencing depth can be necessary to compile sufficient information for identification of a certain pathoge...
Bashir, Alexandra Kristin Wink, Lisa Duller, Stefanie Schwendner, Petra Cockell, Charles Rettberg, Petra Mahnert, Alexander Beblo-Vranesevic, Kristina Bohmeier, Maria Rabbow, Elke
...
Published in
Microbiome
Background Extreme terrestrial, analogue environments are widely used models to study the limits of life and to infer habitability of extraterrestrial settings. In contrast to Earth’s ecosystems, potential extraterrestrial biotopes are usually characterized by a lack of oxygen. Methods In the MASE project (Mars Analogues for Space Exploration), we ...
de Nies, Laura Lopes, Sara Busi, Susheel Bhanu Galata, Valentina Heintz-Buschart, Anna Laczny, Cedric Christian May, Patrick Wilmes, Paul
Published in
Microbiome
Background Pathogenic microorganisms cause disease by invading, colonizing, and damaging their host. Virulence factors including bacterial toxins contribute to pathogenicity. Additionally, antimicrobial resistance genes allow pathogens to evade otherwise curative treatments. To understand causal relationships between microbiome compositions, functi...
Li, Zhiming Xia, Jingjing Jiang, Liuyiqi Tan, Yimei An, Yitai Zhu, Xingyu Ruan, Jie Chen, Zhihua Zhen, Hefu Ma, Yanyun
...
Published in
Microbiome
Background The human skin microbiota is considered to be essential for skin homeostasis and barrier function. Comprehensive analyses of its function would substantially benefit from a catalog of reference genes derived from metagenomic sequencing. The existing catalog for the human skin microbiome is based on samples from limited individuals from a...
Leadbeater, Daniel R. Oates, Nicola C. Bennett, Joseph P. Li, Yi Dowle, Adam A. Taylor, Joe D. Alponti, Juliana Sanchez Setchfield, Alexander T. Alessi, Anna M. Helgason, Thorunn
...
Published in
Microbiome
Background Salt marshes are major natural repositories of sequestered organic carbon with high burial rates of organic matter, produced by highly productive native flora. Accumulated carbon predominantly exists as lignocellulose which is metabolised by communities of functionally diverse microbes. However, the organisms that orchestrate this proces...
Moshkelgosha, Sajad Verhasselt, Hedda Luise Masetti, Giulia Covelli, Danila Biscarini, Filippo Horstmann, Mareike Daser, Anke Westendorf, Astrid M. Jesenek, Christoph Philipp, Svenja
...
Published in
Microbiome
Background Graves’ disease (GD) is an autoimmune condition in which autoantibodies to the thyrotropin receptor (TSHR) cause hyperthyroidism. About 50% of GD patients also have Graves’ orbitopathy (GO), an intractable disease in which expansion of the orbital contents causes diplopia, proptosis and even blindness. Murine models of GD/GO, developed i...
Vigneron, Adrien Cruaud, Perrine Culley, Alexander I. Couture, Raoul-Marie Lovejoy, Connie Vincent, Warwick F.
Published in
Microbiome
Background The sulfur cycle encompasses a series of complex aerobic and anaerobic transformations of S-containing molecules and plays a fundamental role in cellular and ecosystem-level processes, influencing biological carbon transfers and other biogeochemical cycles. Despite their importance, the microbial communities and metabolic pathways involv...
Raimundo, I. Silva, R. Meunier, L. Valente, S. M. Lago-Lestón, A. Keller-Costa, T. Costa, R.
Published in
Microbiome
Background Chitin ranks as the most abundant polysaccharide in the oceans yet knowledge of shifts in structure and diversity of chitin-degrading communities across marine niches is scarce. Here, we integrate cultivation-dependent and -independent approaches to shed light on the chitin processing potential within the microbiomes of marine sponges, o...
Hudspith, Meggie Rix, Laura Achlatis, Michelle Bougoure, Jeremy Guagliardo, Paul Clode, Peta L. Webster, Nicole S. Muyzer, Gerard Pernice, Mathieu de Goeij, Jasper M.
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Published in
Microbiome
Background Sponges are increasingly recognised as key ecosystem engineers in many aquatic habitats. They play an important role in nutrient cycling due to their unrivalled capacity for processing both dissolved and particulate organic matter (DOM and POM) and the exceptional metabolic repertoire of their diverse and abundant microbial communities. ...