Gohil, Nisarg Bhattacharjee, Gargi Singh, Vijai
Published in
Microbial pathogenesis
The emergence of multidrug-resistant (MDR) bacteria is on the rise and the situation has been worsening with each passing day, which is evident from the outpouring number of reports about how more and more pathogens are becoming resistant to even the third and fourth generations of antibiotics. Lately, combination therapies or drug synergy have bee...
Khorramdelazad, Hossein Kazemi, Mohammad Hossein Najafi, Alireza Keykhaee, Maryam Emameh, Reza Zolfaghari Falak, Reza
Published in
Microbial Pathogenesis
• Some clinical and laboratory findings are similar in both influenza and SARS-CoV-2 infections. • COVID-19 may be associated with other respiratory infectious diseases. • Vaccination against influenza at a suitable time is necessary to prevent co-infection.
Tohidinia, Maryam Sefid, Fatemeh
Published in
Microbial pathogenesis
Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus that it disease spreads in over the world. Coronaviruses are single-stranded, positive-sense RNA viruses with a genome of approximately 30 KD, the largest genome among RNA viruses. Most people infected with the COVID-19 virus will experience mild to mod...
Divya, Mani Vijayakumar, Sekar Chen, Jingdi Vaseeharan, Baskaralingam Durán-Lara, Esteban F
Published in
Microbial pathogenesis
SARS-CoV-2 is a causative agent of Coronavirus disease-19 (COVID-19), which is considered as a fatal disease for public health apprehension worldwide. This pathogenic virus can present everywhere. As it is a virus it can extend easily and cause severe illness to humans. Hence, an efficient international attentiveness of plan is necessary to cure an...
Dawood, Ali Adel Altobje, Mahmood Abduljabar
Published in
Microbial Pathogenesis
• Tunicamycin an anticancer drug inhibits the N- linked glycans. Nucleocapsid phosphoprotein is one of the most structural protein of the virus. • The growth of coronavirus in the presence inhibitor tunicamycin resulted in the production of spikeless. • Tunicamycin inhibits E2, S, and M glycoproteins of coronaviruses. • Tunicamycin is also diminish...
Bande, Faruku Arshad, Siti Suri Bejo, Mohd Hair Omar, Abdul Rahman Moeini, Hassan Khadkodae, Saed Wei, Tan Sheau Keong, Yeap Swee Abba, Yusuf Anka, Ibrahim Abubakar
...
Published in
Microbial Pathogenesis
• DNA vaccine could offer promising advantage against infectious bronchitis in poultry. • Vaccination with IBV S-1 gene based DNA vaccine leads to improved antibody and T cell responses. • Encapsulation of the vaccine with chitosan and Saponin enhances the immune response and abrogated the need for multiple booster administration. • The vaccine off...
Fathizadeh, Hadis Taghizadeh, Sepehr Safari, Rohollah Khiabani, Saeid Shabestari Babak, Bayaz Hamzavi, Fatemeh Ganbarov, Khudaverdi Esposito, Silvano Zeinalzadeh, Elham Dao, Sounkalo
...
Published in
Microbial Pathogenesis
• SARS-CoV-2 has now become a public health challenge in most of countries. • SARS-CoV-2 was absent in the sweat samples taken from the foreheads of infected people. • Sweat samples in two patients was contaminated with SARS-CoV-2. • Sweat of the patients with COVID- 19 cannot transmit SARS-CoV-2.
Basu, Soumya Veeraraghavan, Balaji Ramaiah, Sudha Anbarasu, Anand
Published in
Microbial Pathogenesis
• A new commercially available cyclohexanone compound, ZINC07333416 was identified with good pharmacological profile and binding energy when docked with SARS-CoV-2 Main protease (Mpro). • The binding energy is better than that of protease inhibitor Lopinavir, nucleoside analogue Remdesivir. The ligand ZINC07333416 exhibits crucial interactions with...
Pormohammad, Ali Ghorbani, Saied Baradaran, Behzad Khatami, Alireza J Turner, Raymond Mansournia, Mohammad Ali Kyriacou, Demetrios N Idrovo, Juan-Pablo Bahr, Nathan C
Published in
Microbial pathogenesis
In the current time where we face a COVID-19 pandemic, there is no vaccine or effective treatment at this time. Therefore, the prevention of COVID-19 and the rapid diagnosis of infected patients is crucial. We searched all relevant literature published up to February 28, 2020. We used Random-effect models to analyze the appropriateness of the poole...
Li, Zhiwei Ma, Zhiqian Li, Yang Gao, Sheng Xiao, Shuqi
Published in
Microbial Pathogenesis
• Advances in vaccines of PEDV, such as inactivated and attenuated live vaccines, subunit vaccines, and nucleic acid vaccines. • The application of reverse genetics in the development of live attenuated PEDV vaccines. • The roles of PEDV proteins in affecting viral virulence and regulating innate immunity.
