Zheng, Nan Su, Jia Hu, Haochang Wang, Jingqiao Chen, Xiaomin
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
According to the World Health Organization cardiovascular disease risk charts, the mortality rate of cardiovascular diseases in people is still high. The medical expenses caused by cardiovascular diseases are increasing daily, and the medical burden is becoming heavier; as such, it is imperative to prevent and cure cardiovascular diseases. A large ...
Zhao, Xiexiong Dahal, Anu Yang, Qiong Yang, Yan Ding, Zewen Wang, Junwen Swai, Joel Dominic Jiang, Weihong Li, Xiaogang
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Although various antihypertensive medications are available, some hypertensive patients have uncontrolled blood pressures, especially in the clinic. The aim of the present study was to compare the efficacies of various antihypertensive therapies in our hypertension (HTN) clinic (monotherapy vs. combination therapy, fixed-dose combination...
Wang, Hongzhou Zhang, Shunwen Zhao, Haijun Qin, Huiyuan Zhang, Jie Dong, Jiangtao Zhang, Hui Liu, Xiaoling Zhao, Zhengyong Zhao, Yanheng
...
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Carbon monoxide (CO) has anti-inflammatory effects and protects the intestinal mucosal barrier in sepsis. Pyroptosis, or cell death associated with sepsis, is mediated by caspase-1 activation. This study aimed to investigate the role of CO on the expression of proteins associated with intestinal mucosal pyroptosis in a rat model of sepsi...
Golec, Piotr Golec, Joanna
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Treatment of displaced intra-articular calcaneal fractures is controversial. Choosing the optimal surgical technique is very important for patient quality of life and activity. In this study, we asked the question: “What is the long-term quality of life of patients after intra-articular calcaneal fractures treated by minimally invasive r...
Yang, Xiaosong Liu, Xiao Liu, Xiaoguang Yu, Miao Jiang, Ling Ma, Yue Tao, Liyuan Liu, Zhongjun
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Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Circumferential decompression (CD) is an essential treatment option for myelopathy associated with thoracic-ossification of the posterior longitudinal ligament (T-OPLL) when laminectomy cannot achieve sufficient ventral decompression. Although intraoperative neurophysiological monitoring (IONM) is widely used, the operation has a relativ...
Ai, Xiang Liao, Xin Wang, Minhao Hu, Ying Li, Junyan Zhang, Yi Tang, Peng Jiang, Jun
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background The prognostic role of axillary lymph node ratio (LNR) after neoadjuvant chemotherapy (NAC) in breast cancer has not been illuminated. This study was designed to investigate the prognostic role of LNR in breast cancer compared with traditional ypN stage. Material/Methods A total of 306 breast cancer patients diagnosed with positive axill...
Zhang, Yong Han, Bing Wei, Yong Jing, Juehua Li, Jun
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Osteoporotic fractures are common in postmenopausal women and associated with complications. Numerous studies have demonstrated that icariin can be used to treat fractures and osteoporosis. Herein, we evaluated the efficacy of gavage-administered icariin to promote fracture healing in postmenopausal osteoporotic fracture (POF) rats. Mate...
Lu, KeBin Wei, Wenjun Hu, Jiaqian Wen, Duo Ma, Ben Liu, Wanlin Wang, Yu Lu, Zhongwu
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Thyroid cancer, which is the most common endocrine cancer, has shown a drastic increase in incidence globally over the past decade. The present study investigated the thyroid cancer-inhibitory potential of jatrorrhizine-platinum(II) complex (JR-P(II) in vitro and in vivo . Material/Methods The JR-P(II)-mediated cytotoxicity in thyroid ca...
Wang, Jiaxing Huang, Fakun Jiang, Caiyun Chi, Pan
Published in
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background The treatment of cancer is still unable to meet the needs of patients and remains a huge challenge. This study investigated the immune response and anti-cancer effect of silencing STAT3 combined with the use of anti-PD-L1 antibody. Material/Methods Transfected CT26.WT cells were used to subcutaneously inoculate C57B/L6 mice, which were s...
Xu, Zhigang Zuo, Zheng-Qin Gaowa, Baibujiafu Gu, Yuan-Yun Hui, Chen Shen, Yong-Le Xu, Hou-Ping
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Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Laminaria japonica polysaccharide (LJP), a fucose enriched sulfated polysaccharide has been demonstrated to have excellent anticoagulant and antithrombotic activities. However, the antithrombotic effect of low molecular weight polysaccharide from enzymatically modified of LJP (LMWEP) remains unknown. Material/Methods LMWEP was prepared b...
