Booth, Marsilea A Pope, Leon Sherrell, Peter C Stacey, Alastair Tran, Phong A Fox, Kate E
Published in
Materials science & engineering. C, Materials for biological applications
Titanium-based implants are the leading material for orthopaedic surgery, due to their strength, versatility, fabrication via additive manufacturing and invoked biological response. However, the interface between the implant and the host tissue requires improvement to better integrate the implant material and mitigate foreign body response. The int...
Li, Ping Zhang, Wentai Spintzyk, Sebastian Schweizer, Ernst Krajewski, Stefanie Alexander, Dorothea Dai, Jingtao Xu, Shulan Wan, Guojiang Rupp, Frank
...
Published in
Materials science & engineering. C, Materials for biological applications
Biodegradable zinc (Zn) and Zn-based alloys have been recognized as promising biomaterials for biomedical implants. Sterilization is an essential step in handling Zn-based implants before their use in clinical practice and there are various sterilization methods are available. However, how these treatments influence the Zn-based biomaterials remain...
Wu, Hong Yang, Si Xiao, Jian Ouyang, Zhengxiao Yang, Minghua Zhang, Mingming Zhao, Dapeng Huang, Qianli
Published in
Materials science & engineering. C, Materials for biological applications
Biomaterials with multi-functions including enhancing osteogenesis, inhibiting osteoclastogenesis and effectively removing bacteria are urgently needed in the treatment of osteoporotic bone defects. In this study, MgO nano-particles were employed as a platform for precise Cu2+ loading. By immersing MgO into CuSO4 solution with a pre-defined concent...
Cerqueni, Giorgia Scalzone, Annachiara Licini, Caterina Gentile, Piergiorgio Mattioli-Belmonte, Monica
Published in
Materials science & engineering. C, Materials for biological applications
The presence of Reactive Oxygen Species (ROS) in bone can influence resident cells behaviour as well as the extra-cellular matrix composition and the tissue architecture. Aging, in addition to excessive overloads, unbalanced diet, smoking, predisposing genetic factors, lead to an increase of ROS and, if it is accompanied with an inappropriate produ...
Sun, Xiaohao Yu, Xiao Li, Wei Chen, Minfang Liu, Debao
Published in
Materials science & engineering. C, Materials for biological applications
The development of biodegradable Zn matrix composites has been considered a promising approach to achieving enhanced mechanical properties, controllable degradation rate, good biocompatibility, and good osseointegration as orthopedic implants. However, scant literature regarding Zn matrix composites has been reported because of the great difficulty...
Chen, Wenliang Yang, Jingzhou Kong, Hui Helou, Mark Zhang, Dachen Zhao, Jinhui Jia, Weitao Liu, Qian He, Peidong Li, Xiaopeng
...
Published in
Materials science & engineering. C, Materials for biological applications
Laser powder bed fusion (LPBF) additive manufacturing of pure tantalum and their graded lattice structures was systematically investigated, with emphasis on their microstructure evolution, phase formation, surface energy and biological properties in comparison with conventionally forged pure Ta. The LPBF fabricated Ta (LPBF-Ta) exhibited lower cont...
Al-Bishari, Abdullrahman M Yie, Kendrick Hii Ru Al-Baadani, Mohammed A Al-Shaaobi, Bilal A Zhou, Zixin Fang, Kai Sun, Anba Shen, Yiding Cai, Lei Yao, Lili
...
Published in
Materials science & engineering. C, Materials for biological applications
Hydrogen sulfide (H2S) has been as an essential gasotransmitter and a potential therapeutic approach for several biomedical treatments such as cardiovascular disorders, hypertension, and other diseases. The endogenous and exogenous H2S also plays a crucial role in the bone anabolic process and a protective mechanism in cell signalling. In this stud...
Gögele, Clemens Wiltzsch, Sven Lenhart, Armin Civilleri, Aurelio Weiger, Thomas Martin Schäfer-Eckart, Kerstin Minnich, Bernd Forchheimer, Lukas Hornfeck, Markus Schulze-Tanzil, Gundula
...
Published in
Materials science & engineering. C, Materials for biological applications
Cartilage injuries remain challenging since the regenerative capacity of cartilage is extremely low. The aim was to design a novel type of bioactive glass (BG) scaffold with suitable topology that allows the formation of cartilage-specific extracellular matrix (ECM) after colonization with chondrogenic cells for cartilage repair. Highly porous scaf...
Pien, Nele Pezzoli, Daniele Van Hoorick, Jasper Copes, Francesco Vansteenland, Margot Albu, Madalina De Meulenaer, Bruno Mantovani, Diego Van Vlierberghe, Sandra Dubruel, Peter
...
Published in
Materials science & engineering. C, Materials for biological applications
The present work targets the development of collagen-based hydrogel precursors, functionalized with photo-crosslinkable methacrylamide moieties (COL-MA), for vascular tissue engineering (vTE) applications. The developed materials were physico-chemically characterized in terms of crosslinking kinetics, degree of modification/conversion, swelling beh...
Baniasadi, Hossein Madani, Zahraalsadat Ajdary, Rubina Rojas, Orlando J Seppälä, Jukka
Published in
Materials science & engineering. C, Materials for biological applications
We proposed a simple method to process hydrogels containing polyvinyl alcohol and cellulose nanofibrils (PVA/CNF) to prepare volumetric architectures by direct ink writing (DIW). The presence of CNF in the aqueous PVA suspensions conferred rheology profiles that were suitable for extrusion and solidification in pre-designed shapes. The viscoelastic...
