Massamba, Laurencie Madamet, Marylin Benoit, Nicolas Chevalier, Alicia Fonta, Isabelle Mondain, Véronique Jeandel, Pierre-Yves Amalvict, Rémy Delaunay, Pascal Mosnier, Joel
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Published in
Malaria Journal
BackgroundThe drug combination atovaquone–proguanil, is recommended for treatment of uncomplicated falciparum malaria in France. Despite high efficacy, atovaquone–proguanil treatment failures have been reported. Resistance to cycloguanil, the active metabolite of proguanil, is conferred by multiple mutations in the Plasmodium falciparum dihydrofola...
Yan, Shirley D. Orkis, Jennifer Khan Sohail, Saifra Wilson, Sean Davis, TrishAnn Storey, J. Douglas
Published in
Malaria Journal
BackgroundAlthough Guyana has made significant progress toward malaria control, limited access to malaria testing and treatment services threatens those gains. Mining activities create breeding environments for mosquitoes, and the migrant and mobile mining populations are hard to reach with information and services. The Ministry of Public Health (M...
Somé, Fabrice A. Bazié, Thomas Ehrlich, Hanna Y. Goodwin, Justin Lehane, Aine Neya, Catherine Zachari, Kabré Wade, Martina Ouattara, Jean-Marie Foy, Brian D.
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Published in
Malaria Journal
BackgroundSince 2014, seasonal malaria chemoprevention (SMC) with amodiaquine–sulfadoxine–pyrimethamine (AQ–SP) has been implemented on a large scale during the high malaria transmission season in Burkina Faso. This paper reports the prevalence of microscopic and submicroscopic malaria infection at the outset and after the first round of SMC in chi...
Aviles, Erica I. Rotenberry, Rachel D. Collins, C. Mathilda Dotson, Ellen. M. Benedict, Mark Q.
Published in
Malaria Journal
BackgroundMarking mosquitoes is vital for mark-release-recapture and many laboratory studies, but their small size precludes the use of methods that are available for larger animals such as unique identifier tags and radio devices. Fluorescent dust is the most commonly used method to distinguish released individuals from the wild population. Numero...
van Eijk, Anna Maria Mannan, Asad S. Sullivan, Steven A. Carlton, Jane M.
Published in
Malaria Journal
BackgroundMalaria is a major public health problem in India. Data from surveys totaling 3031 participants at three sites revealed a high proportion of asymptomatic infections, complicating diagnosis. The aim of this study was to identify differences in complaints and symptoms between sites, and factors associated with asymptomatic Plasmodium infect...
de Azevedo-Quintanilha, Isaclaudia G. Medeiros-de-Moraes, Isabel M. Ferreira, André C. Reis, Patrícia A. Vieira-de-Abreu, Adriana Campbell, Robert A. Weyrich, Andrew S. Bozza, Patricia T. Zimmerman, Guy A. Castro-Faria-Neto, Hugo C.
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Published in
Malaria Journal
BackgroundMalaria-triggered lung injury can occur in both severe and non-severe cases. Platelets may interact with parasitized erythrocytes, leukocytes and endothelium. These interactions can lead to microvessel obstructions and induce release of inflammatory mediators. Induction of the haem oxygenase enzyme is important in the host’s response to f...
Vareta, Jimmy Buchwald, Andrea G. Barrall, Angelica Cohee, Lauren M. Walldorf, Jenny A. Coalson, Jenna E. Seydel, Karl Sixpence, Alick Mathanga, Don P. Taylor, Terrie E.
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Published in
Malaria Journal
BackgroundSubmicroscopic Plasmodium falciparum infections are widespread in many areas. However, the contribution of these infections to symptomatic malaria is not well understood. This study evaluated whether participants with submicroscopic P. falciparum infections have higher prevalence of fever than uninfected participants in southern Malawi.Me...
Kumar, Ramesh Farzeen, Midhat Hafeez, Assad Achakzai, Baseer Khan Vankwani, Muskan Lal, Manohar Iqbal, Rabia Somrongthong, Ratana
Published in
Malaria Journal
BackgroundAbout one quarter of pregnant women in the population of Pakistan are using long-lasting insecticide-treated bed nets (LLINs) for prevention of malaria. Past research reported that adequate information and education would act as mediator to change behaviour among patients for prevention of malaria infection. The effective use of LLINs wou...
Tahghighi, Azar Mohamadi-Zarch, Seyed-Mahdi Rahimi, Hamzeh Marashiyan, Mahya Maleki-Ravasan, Naseh Eslamifar, Ali
Published in
Malaria Journal
BackgroundResistance of Plasmodium falciparum against common anti-malarial drugs emphasizes the need of alternative and more effective drugs. Synthetic derivatives of 1-(heteroaryl)-2-((5-nitroheteroaryl)methylene) hydrazine have showed in vitro anti-plasmodial activities. The present study aimed to evaluate the molecular binding and anti-plasmodia...
Bisoffi, Zeno Bertoldi, Marco Silva, Ronaldo Bertoli, Giulia Ursini, Tamara Marocco, Stefania Piubelli, Chiara Pomari, Elena Buonfrate, Dora Gobbi, Federico
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Published in
Malaria Journal
BackgroundMalaria is a major travel medicine issue. Retrospective confirmation of a malaria episode diagnosed in an endemic area can have relevant implications in transfusional medicine in Europe, where blood donors are excluded from donation on the basis of positive malaria serology. However, there is scarce evidence on the dynamics of anti-malari...
