Progress in the treatment paradigms for locally advanced cervical cancer.
Published in Lancet (London, England)
Published in Lancet (London, England)
Published in Lancet (London, England)
Locally advanced cervical cancer is treated with chemoradiotherapy (standard of care), but many patients still relapse and die from metastatic disease. We investigated chemoradiotherapy with or without induction chemotherapy to determine whether induction chemotherapy improves both progression-free survival and overall survival. The INTERLACE trial...
Published in Lancet (London, England)
Published in Lancet (London, England)
Published in Lancet (London, England)
Published in Lancet (London, England)
Background Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain. Methods RADICALS-HD was a randomised contro...
Published in Lancet (London, England)
Background Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear. Methods RADICALS...
Published in Lancet (London, England)
Published in Lancet (London, England)
Published in Lancet (London, England)