ul Islam, Tanveer Wang, Ye Aggarwal, Ishu Cui, Zhiwei Eslami Amirabadi, Hossein Garg, Hemanshul Kooi, Roel Venkataramanachar, Bhavana B. Wang, Tongsheng Zhang, Shuaizhong
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Published in
Lab on a Chip
Bioinspired artificial cilia can provide microfluidic functions like flow generation, particle transport and flow sensing. This critical review broadly describes the progress in artificial cilia research and evaluates its future potential.
Szafraniec, Hannah M. Valdez, José M. Iffrig, Elizabeth Lam, Wilbur A. Higgins, John M. Pearce, Philip Wood, David K.
Published in
Lab on a Chip
We present a method that combines microfluidic systems and object-tracking computational technologies to evaluate the contributions of effective viscosity and wall friction to the overall resistance in blood from patients with sickle cell disease.
Abbott, Jeffrey Mukherjee, Avik Wu, Wenxuan Ye, Tianyang Jung, Han Sae Cheung, Kevin M. Gertner, Rona S. Basan, Markus Ham, Donhee Park, Hongkun
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Published in
Lab on a Chip
A CMOS-MEA device combined with new impedance and electrochemical techniques measures cell attachment, growth/wound healing, cell–cell adhesion, metabolic state, and redox properties with single-cell spatial resolution for cell-biology applications.
Girardin, Sophie Clément, Blandine Ihle, Stephan J. Weaver, Sean Petr, Jana B. Mateus, José C. Duru, Jens Krubner, Magdalena Forró, Csaba Ruff, Tobias
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Published in
Lab on a Chip
We present a method to build microcircuits of human induced pluripotent stem cell (iPSC)-derived neurons with a controlled topology. The circuits are compatible with imaging and microelectrode array experiments.
Vivas, Aisen van den Berg, Albert Passier, Robert Odijk, Mathieu van der Meer, Andries D.
Published in
Lab on a Chip
Translational Organ-on-Chip Platform (TOP) is a multi-institutional effort to develop an open platform for automated organ-on-chip culture that actively facilitates the integration of components from various developers.
Elvira, Katherine S. Gielen, Fabrice Tsai, Scott S. H. Nightingale, Adrian M.
Published in
Lab on a Chip
When making a droplet flow device what material should you use? What fabrication methods are available and will surface treatments be required? This review offers a guide, with examples, to making robust droplet flow devices.
Zhang, Yan Kim, Sungho Shi, Weihua Zhao, Yaoyao Park, Insu Brenden, Christopher Iyer, Hrishikesh Jha, Prasoon Bashir, Rashid Sweedler, Jonathan V.
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Published in
Lab on a Chip
We report on a silicon microfluidic platform that enables integration of transparent μm-scale microfluidic channels, an on-chip pL-volume droplet generator, and a nano-electrospray ionization emitter that enables spatial and temporal phase separation for mass spectrometry analysis.
Ardila Riveros, Jessi Carolina Blöchinger, Anna Karolina Atwell, Scott Moussus, Michel Compera, Nina Rajabnia, Omid Georgiev, Tihomir Lickert, Heiko Meier, Matthias
Published in
Lab on a Chip
Here we developed an automated mLSI chip platform with general analytical workflow for 3D stem cell cultures offers the optimization of in vitro generation of various cell types for cell replacement therapies.
Gerlt, M S Ruppen, P Leuthner, M Panke, S Dual, J
Published in
Lab on a chip
Comprehensive integration of process steps into a miniaturised version of synthetic biology workflows remains a crucial task in automating the design of biosystems. However, each of these process steps has specific demands with respect to the environmental conditions, including in particular the composition of the surrounding fluid, which makes int...
Mainardi, Andrea Carminati, Francesca Ugolini, Giovanni Stefano Occhetta, Paola Isu, Giuseppe Robles Diaz, Diana Reid, Gregory Visone, Roberta Rasponi, Marco Marsano, Anna
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Published in
Lab on a chip
Cardiac fibrosis is a maladaptive remodeling of the myocardium hallmarked by contraction impairment and excessive extracellular matrix deposition (ECM). The disease progression, nevertheless, remains poorly understood and present treatments are not capable of controlling the scarring process. This is partly due to the absence of physiologically rel...