Laser particle activated cell sorting in microfluidics †
Published in Lab on a Chip
A microfluidic device is developed that uses the narrowband optical radiation of laser particle barcodes to sort tagged cells.
Systematic characterization of effect of flow rates and buffer compositions on double emulsion droplet volumes and stabi...
Published in Lab on a Chip
Measured double emulsion droplet sizes across hundreds of flow rate and surfactant conditions parameterize core/shell volumes and droplet stability.
Microscopic artificial cilia - a review.
...Published in Lab on a chip
Cilia are microscopic hair-like external cell organelles that are ubiquitously present in nature, also within the human body. They fulfill crucial biological functions: motile cilia provide transportation of fluids and cells, and immotile cilia sense shear stress and concentrations of chemical species. Inspired by nature, scientists have developed ...
Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood †
Published in Lab on a Chip
We present a method that combines microfluidic systems and object-tracking computational technologies to evaluate the contributions of effective viscosity and wall friction to the overall resistance in blood from patients with sickle cell disease.
Multi-parametric functional imaging of cell cultures and tissues with a CMOS microelectrode array †
...Published in Lab on a Chip
A CMOS-MEA device combined with new impedance and electrochemical techniques measures cell attachment, growth/wound healing, cell–cell adhesion, metabolic state, and redox properties with single-cell spatial resolution for cell-biology applications.
Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings †
...Published in Lab on a Chip
We present a method to build microcircuits of human induced pluripotent stem cell (iPSC)-derived neurons with a controlled topology. The circuits are compatible with imaging and microelectrode array experiments.
Fluidic circuit board with modular sensor and valves enables stand-alone, tubeless microfluidic flow control in organs-o...
Published in Lab on a Chip
Translational Organ-on-Chip Platform (TOP) is a multi-institutional effort to develop an open platform for automated organ-on-chip culture that actively facilitates the integration of components from various developers.
Materials and methods for droplet microfluidic device fabrication
Published in Lab on a Chip
When making a droplet flow device what material should you use? What fabrication methods are available and will surface treatments be required? This review offers a guide, with examples, to making robust droplet flow devices.
Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform †
...Published in Lab on a Chip
We report on a silicon microfluidic platform that enables integration of transparent μm-scale microfluidic channels, an on-chip pL-volume droplet generator, and a nano-electrospray ionization emitter that enables spatial and temporal phase separation for mass spectrometry analysis.
Automated optimization of endoderm differentiation on chip †
Published in Lab on a Chip
Here we developed an automated mLSI chip platform with general analytical workflow for 3D stem cell cultures offers the optimization of in vitro generation of various cell types for cell replacement therapies.
