Published in Lab on a Chip
Bioinspired artificial cilia can provide microfluidic functions like flow generation, particle transport and flow sensing. This critical review broadly describes the progress in artificial cilia research and evaluates its future potential.
Published in Lab on a Chip
We present a method that combines microfluidic systems and object-tracking computational technologies to evaluate the contributions of effective viscosity and wall friction to the overall resistance in blood from patients with sickle cell disease.
Published in Lab on a Chip
A CMOS-MEA device combined with new impedance and electrochemical techniques measures cell attachment, growth/wound healing, cell–cell adhesion, metabolic state, and redox properties with single-cell spatial resolution for cell-biology applications.
Published in Lab on a Chip
We present a method to build microcircuits of human induced pluripotent stem cell (iPSC)-derived neurons with a controlled topology. The circuits are compatible with imaging and microelectrode array experiments.
Published in Lab on a Chip
Translational Organ-on-Chip Platform (TOP) is a multi-institutional effort to develop an open platform for automated organ-on-chip culture that actively facilitates the integration of components from various developers.
Published in Lab on a Chip
When making a droplet flow device what material should you use? What fabrication methods are available and will surface treatments be required? This review offers a guide, with examples, to making robust droplet flow devices.
Published in Lab on a Chip
We report on a silicon microfluidic platform that enables integration of transparent μm-scale microfluidic channels, an on-chip pL-volume droplet generator, and a nano-electrospray ionization emitter that enables spatial and temporal phase separation for mass spectrometry analysis.
Published in Lab on a Chip
Here we developed an automated mLSI chip platform with general analytical workflow for 3D stem cell cultures offers the optimization of in vitro generation of various cell types for cell replacement therapies.
Published in Lab on a chip
Comprehensive integration of process steps into a miniaturised version of synthetic biology workflows remains a crucial task in automating the design of biosystems. However, each of these process steps has specific demands with respect to the environmental conditions, including in particular the composition of the surrounding fluid, which makes int...
Published in Lab on a chip
Cardiac fibrosis is a maladaptive remodeling of the myocardium hallmarked by contraction impairment and excessive extracellular matrix deposition (ECM). The disease progression, nevertheless, remains poorly understood and present treatments are not capable of controlling the scarring process. This is partly due to the absence of physiologically rel...
