Jouvin, M H Kazatchkine, M
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation a...
Saubier, E C Faysse, E Gouillat, C
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Twenty-one patients in a series of 283 treated surgically for primary hyperparathyroidism between 1960 and 1982, underwent reoperation. Eleven had been previously treated elsewhere. The initial cervicotomy was negative in fourteen cases, but had led to the ablation of one or more adenomas in seven. The reason for reoperation was recurrence or persi...
Maggiore, G Marzani, D De Giacomo, C Sessa, F Civardi, G Scotta, M S
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Clinical, biochemical and histological features of chronic hepatitis type B were studied in 29 children aged 8 months to 13 years. On entry into the study, all were known to have had hepatitis B surface antigen (HBsAg) with elevated serum transaminase levels for at least six months. A possible source of infection was found in 15 children. When they...
Dumont, D Manigand, G Taillandier, J Cohen De Lara, A
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Osteoradionecrosis (ORN) is not exceptional, despite advances in irradiation techniques. Six cases are reported, involving the pelvis, coxofemoral joint, mandible and vertebrae; in this last case, the semiologic value of the lucent intrasomatic image seen on plain films and tomographies of the vertebrae is underscored. The irradiation dose (above 3...
Auplat, P Janin-Manificat, L Marchal, G Besancentot, J F Cortet, P
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
We report the case of an 85-year-old man with perfectly controlled hypertension and coronary insufficiency who presented with typical giant cell arteritis (GCA). Thirty-six hours after initiation of prednisolone therapy (1 mg/kg/d), acute coronary insufficiency with non-transmural infarction occurred. Outcome was favorable despite disturbances in h...
Vacher-Lavenu, M C Baron-Selme, V Abelanet, R Boissonnas, A Laroche, C
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
A case of idiopathic splenomegaly with ceroid histiocytosis--the so-called sea-blue histiocytosis--is reported with reference to the literature. The histological, histochemical and ultrastructural features of stained sea-blue and ceroid-containing macrophages are described and their physiopathological significance is discussed. Attention is drawn t...
Messmer, J C Lecaillon-Thibon, E Soler, H
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
The aim of this study is to determine the best antibiotic in presumptive staphylococcal infection and/or bacteriologically established staphylococcal infection before results of antibiotic sensitivity tests are available. 382 strains were analyzed. Only sensitivity or resistance to antibiotics were considered. Vancomycin is the best antistaphylococ...
Guillevin, L Karambinis, A Bletry, O Hillion, D Delrieu, F Menkes, C Pagniez, G Godeau, P
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Four cases of monoclonal gammopathy associated with polyarteritis nodosa are reported. In view of the chronology of events and course of the disease, the connections between protein peak and polyarteritis nodosa can be considered. Management of polyarteritis nodosa is discussed according to the existence of a peak which may originate in myeloma. Th...
Gombe Mbalawa, C Mobengo, P
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
With reference to two cases of Von Recklinghausen disease with malignant transformation the authors present the clinical features related to this transformation and the poor therapeutic results.
Bonvoisin, B
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Rheumatoid arthritis (RA) is an autoimmune disease whose diagnosis was long based solely upon the demonstration of rheumatoid factors (RF) which are IgM antibodies with anti-IgG specificity. The development of modern techniques which are more sensitive and/or detect non-IgM rheumatoid factors has reduced the percentage of presumptive seronegative R...
