[Diffuse angiomatous lesions].
Published in La Revue de medecine interne
[Hypercholesterolemia, from screening to treatment: Who, why and how to manage].
Published in La Revue de medecine interne
Hypercholesterolemia refers to dyslipidemia with an increased circulating cholesterol levels. This is the most common dyslipidemia and is associated with an increased risk of developing atheromatous cardiovascular diseases. One of the major challenges in primary prevention is to define the threshold for therapeutic intervention that allow to obtain...
[A plantar pain].
Published in La Revue de medecine interne
[The CD40-CD40L axis: Current and future implications in clinical immunology].
Published in La Revue de medecine interne
The CD40-CD40 ligand (CD40L) pathway is a backbone of communication between cells of the immune system. It makes it possible to generate a proinflammatory signal and thus participates in the pathogenesis of dysimmune diseases, transplant rejection and atherosclerosis. Because of this therapeutic target of choice, several generations of anti-CD40L m...
[Characteristics of patients with connective tissue disease-associated pulmonary arterial hypertension treated with pros...
Published in La Revue de medecine interne
Pulmonary arterial hypertension (PAH) is a severe complication of connective tissue disease (CTD). Data on use of prostanoids in this particular subset of patients are lacking. We aimed to describe the characteristics of patients with PAH-CTD treated with prostanoids and the outcomes under treatment. In this multicenter retrospective study, all pat...
[Thrombocytosis in a 56 year-old woman].
...Published in La Revue de medecine interne
[Assessment of the Internal Medicine Multidisciplinary Team meetings at the Grenoble University Hospital].
Published in La Revue de medecine interne
Multidisciplinary team (MDT) meetings purpose is to optimize the disease management regarding state of science. While cancer MDT has proven its effectiveness, this is not yet the case with internal medicine MDT. We performed a descriptive monocentric retrospective study. Data were collected from 247 MDT meeting reports which took place at the Greno...
[Human papillomavirus and systemic lupus erythematosus].
Published in La Revue de medecine interne
Infection with human papillomavirus (HPV) is one of the most widespread sexually transmitted diseases and the main risk factor for cervical cancer. Underlying conditions, like immunosuppression, favour the persistence and the progression of cervical lesions to an aggressive form. Patients with autoimmune diseases, and particularly systemic lupus er...
[Periodic fever syndrome associated with mutations in the TNF type 1 receptor gene: A differential diagnosis of familial...
...Published in La Revue de medecine interne
Tumor Necrosis Factor Type 1 Receptor Associated Periodic Syndrome (TRAPS) is a rare autosomal dominant autosomal autoinflammatory disease associated with mutations in the TNF type 1 receptor gene (TNFRSF1A). It is characterized by relatively long recurrent febrile seizures with an average duration of 7 days accompanied by arthralgia, myalgia, and ...
[Common variable immunodeficiency disorders: Updated diagnostic criteria and genetics].
Published in La Revue de medecine interne
Common variable immunodeficiency disorders (CVID) are a heterogeneous group of conditions with hypogammaglobulinemia as the common denominator. These are the most common symptomatic primary immunodeficiency disorder in adults. Two different clinical forms are described: one group only develops infections, while a second includes (sometimes without ...
