20 years of EURETINA: 20 years of progress
Published in Kompass Ophthalmologie
Eye injuries due to private fireworks and firecrackers
Published in Kompass Ophthalmologie
Background: On festive days worldwide eyes are severely injured by fireworks. The data on the number and severity are to date not registered in Germany. Objective: How frequent are firework-induced injuries in Germany, who are the affected, how serious are the injuries, which forms of treatment are necessary and how frequent are accompanying injuri...
Impact of Intravitreal Ranibizumab Therapy on Vision Outcomes in Diabetic Macular Edema Patients: A Meta-Analysis
Published in Kompass Ophthalmologie
Purpose: Evaluation of the impact of the injection frequency of ranibizumab on best-corrected visual acuity (BCVA) outcomes in patients with diabetic macular edema (DME). Methods: A meta-analysis of randomized controlled trials (RCTs) and real-world studies was performed to quantify the effect of ranibizumab treatment on BCVA and central foveal thi...
Long-term outcome of patients with pars plana vitrectomy following rhegmatogenous retinal detachment
Published in Kompass Ophthalmologie
Purpose: To determine the long-term outcome of patients operated with pars plana vitrectomy (PPV) for primary rhegmatogenous retinal detachment (RRD) and to identify potential predictors for poor visual outcome. Methods: Prospective, observational 30-month study of patients operated for primary RRD with PPV. Examinations were performed preoperative...
Uveitis on nivolumab: When it rains, it pours...
Published in Kompass Ophthalmologie
Nivolumab is an anti-programmed cell death protein 1 monoclonal antibody that is used to treat metastatic cutaneous malignant melanoma. Although bilateral uveitis has been reported as a side effect of nivolumab administration, there are few reports of Vogt-Koyanagi-Harada disease (VKH)-like uveitis. We report such a case. A 63-year-old woman with m...
Fundus image analysis through a self-learning machine: Computer determines risk factors in hypertension
Published in Kompass Ophthalmologie
Traditionally, medical discoveries are made by observing associations, making hypotheses from them and then designing and running experiments to test the hypotheses. However, with medical images, observing and quantifying associations can often be difficult because of the wide variety of features, patterns, colours, values and shapes that are prese...
Myopic choroidal neovascularisation – Use the patient’s motivation
Published in Kompass Ophthalmologie
Purpose: The aim of this study was to evaluate the 9-year outcome of ranibizumab monotherapy for myopic choroidal neovascularization (mCNV). Methods: This was a retrospective, nonrandomized, multicentric study to evaluate the long-term outcomes of mCNV treated with ranibizumab monotherapy for at least 9 years according to a strict pro re nata regim...
Diabetic macular oedema: structural and functional results of sequential dexamethasone and aflibercept therapy after one...
Published in Kompass Ophthalmologie
Objective: The aim of this paper is to compare intravitreous aflibercept versus dexamethasone implant followed by aflibercept (sequential treatment group) in patients with diabetic macular edema (DME). Methods: We conducted an observational retrospective study in naïve DME patients, 15 treated only with aflibercept (a monthly injection for the firs...
Non-inflammatory posterior uveitis – Diagnosis and therapy
Published in Kompass Ophthalmologie
Background: Posterior uveitis is a rare, potentially serious condition. In Central Europe and the USA, the incidence of intraocular inflammation is approximately 115/100,000 and of these cases, 12–15% suffer from posterior uveitis. This disease occurs more frequently in adults than in children. The disease description of “posterior uveitis” include...
Prognostic factors for visual acuity in pseudophakic patients with epiretinal gliosis and macular surgery
Published in Kompass Ophthalmologie
Purpose: To evaluate the visual prognostic factors in patients with pseudophakic epiretinal membrane (ERM) after vitrectomy using spectral domain optical coherence tomography (SD-OCT). Methods: A retrospective review of patients with pseudophakic ERM having undergone vitrectomy was conducted. Best corrected visual acuity (BCVA) and SD-OCT were cond...
