7 Fragen an Dr. Karl Stock und M.Sc. Steffen Nothelfer, Otto von Guericke-Preisträger 2020
Published in Kompass Dermatologie
Psoriasis: Anti-IL17-Antikörper auch bei älteren Menschen einsetzbar
Published in Kompass Dermatologie
Anti-interleukin-17 agents have recently been developed for the treatment of psoriasis. This study evaluated the tolerance and effectiveness of anti-interleukin-17 agents for psoriasis in elderly patients in daily practice. A multicentre, retrospective study was performed, involving psoriatic patients aged ≥65 years who had received an anti-interle...
Atopische Dermatitis: Dermatologische Systemtherapie in Zeiten der COVID-19-Pandemie
Published in Kompass Dermatologie
Atopic dermatitis (AD) is a complex disease with elevated risk of respiratory comorbidities. Severely affected patients are often treated with immune-modulating systemic drugs. On March 11th 2020, the World Health Organization declared the 2019 novel coronavirus severe acute respiratory syndrome (SARS-Cov-2) epidemic to be a pandemic. The number of...
Start frei für 2021
Published in Kompass Dermatologie
Atopische Dermatitis: Kombination aus Dupilumab und Kortikosteroid auch bei 6- bis 11-Jährigen erfolgreich
Published in Kompass Dermatologie
Background: Children with severe atopic dermatitis (AD) have limited treatment options. Objective: We report the efficacy and safety of dupilumab + topical corticosteroids (TCS) in children aged 6–11 years with severe AD inadequately controlled with topical therapies. Methods: In this double-blind, 16-week, phase 3 trial (NCT03345914), 367 patients...
Transhumanismus: Welchen Menschen wollen wir?
Published in Kompass Dermatologie
COVID-19: Risiko für Patienten mit chronisch entzündlichen Erkrankungen?
Published in Kompass Dermatologie
COVID-19, caused by the SARS-CoV-2 virus, has become pandemic. With sharply rising infection rates, patient groups characterized by an enhanced infection risk will be challenged by the virus. In this context, patients with chronic immune-mediated inflammatory diseases are of particular interest, as these diseases are characterized by an intrinsic i...
Kompressionstherapie: Wie nach der Sklerosierungsbehandlung die besten Ergebnisse erzielt werden können
Published in Kompass Dermatologie
Background: Sclerotherapy is considered to be the method of choice for the treatment of telangiectatic varicose veins (C1 veins). Whereas the use of compression stockings after sclerotherapy is recommended, little is known about the impact of compression on the outcome of sclerotherapy. The aim of this study was to assess the influence of compressi...
Aktinische Keratose: Drei therapeutische Verfahren im direkten Vergleich
Published in Kompass Dermatologie
Background: The efficacy for actinic keratosis (AK) clearance of field-directed treatments has been investigated in randomized studies against placebo, but the comparison of results is difficult for several methodological reasons. Objectives: The present study aims to compare efficacy of MAL-photodynamic therapy (MAL-PDT), ingenol mebutate gel (IMB...
Basalzellkarzinom: Hedgehog-Pathway-Inhibitoren bei lokal fortgeschrittenen oder metastasierten Tumoren
Published in Kompass Dermatologie
Die Publikation von Dummer et al. beschreibt die Daten zur Effektivität und Sicherheit des Hedgehog pathway Inhibitors (HPI) Sonidegib in der abschließenden 42-Monatsanalyse der BOLT (basal cell carcinoma outcomes with LDE225 (sonidegib) treatment) Studie. Ursprünglich wurden 230 erwachsene, nicht systemisch mit HPI vorbehandelte Patienten mit Basa...
