Duan, Yong-Chang Shi, Lin Jin, Zheng Hu, Meng Huang, Hao Yan, Tao Zhang, Kun-Ru
Published in
Kidney and Blood Pressure Research
Background: Hypertensive nephropathy is one of the major causes of ESRD. Exercise has been considered a nonpathological therapy for hypertension and its complications, yet mechanisms remain unclear. We sought to investigate whether periodic swimming could ameliorate hypertension-induced kidney dysfunction and its underlying mechanisms. Methods: Fou...
Floris, Matteo Lepori, Nicola Angioi, Andrea Cabiddu, Gianfranca Piras, Doloretta Loi, Valentina Swaminathan, Sundararaman Rosner, Mitchell H. Pani, Antonello
Published in
Kidney and Blood Pressure Research
Background: Epidemics of chronic kidney disease of uncertain etiology (CKDu) are occurring on the Pacific coast of Central America, in Sri Lankan and Indian agricultural communities, and in other hotspots around the world. CKDu primarily affects male agricultural workers, and traditional risk factors such as diabetes and hypertension are not involv...
Umetsu, Hidenori Watanabe, Shojiro Imaizumi, Tadaatsu Aizawa, Tomomi Tsugawa, Koji Kawaguchi, Shogo Seya, Kazuhiko Matsumiya, Tomoh Tanaka, Hiroshi
Published in
Kidney and Blood Pressure Research
Background: Although toll-like receptor 3 (TLR3) signaling is involved in the development of certain chronic kidney diseases, the specific molecular mechanisms underlying inflammatory reactions via activation of TLR3 signaling in human podocytes remain unclear. Interleukin (IL)-6 is a pleiotropic cytokine associated with innate and adaptive immune ...
Wan, Elizabeth R. Unwin, Robert Walsh, Stephen B.
Published in
Kidney and Blood Pressure Research
Chu, Yuguang Zhou, Yan Lu, Shihua Lu, Feng Hu, Yuanhui
Published in
Kidney and Blood Pressure Research
Background: The underlying pathogenesis of patients with salt-sensitive hypertension expressing higher blood pressure and severer renal damage remains uncertain. Methods: We recruited 329 subjects, 131 in salt-sensitive (SS) group, 148 in nonsalt-sensitive (NSS) group, and 50 healthy people in normal group and tested their renal function, 24-h ambu...
Ortega-Martinez, Marta Gutierrez-Davila, Vanessa Gutierrez-Arenas, Esthefania Niderhauser-Garcia, Alberto Cerda-Flores, Ricardo M. Jaramillo-Rangel, Gilberto
Published in
Kidney and Blood Pressure Research
Introduction: The diameter and area of the proximal convoluted tubule (PCT) and the distal convoluted tubule (DCT) are of the main parameters analyzed in stereological studies of the kidney. However, there is no consensus about if the PCT and DCT should be considered circular or elliptical in shape. Objective: To analyze if there are significant di...
Leyssens, Katrien Van Regenmortel, Niels Roelant, Ella Guerti, Khadija Couttenye, Marie Madeleine Jorens, Philippe G. Verbrugghe, Walter Van Craenenbroeck, Amaryllis H.
Published in
Kidney and Blood Pressure Research
Introduction: Acute kidney injury (AKI) is a frequent complication among patients in the intensive care unit (ICU). The limitations of serum Cr (sCr) in timely detecting AKI are well known. Beta-trace protein (BTP) is emerging as a novel endogenous glomerular filtration rate marker. The aim of this study was to explore the role of BTP as a marker o...
Myers, Jonathan Chan, Khin Chen, Yu Lit, Yiming Patti, Alessandro Massaband, Payam Kiratli, B. Jenny Tamura, Manju Chertow, Glenn M. Rabkin, Ralph
...
Published in
Kidney and Blood Pressure Research
Background: Patients on maintenance hemodialysis (MHD) exhibit muscle wasting and impaired physical function which can be reversed with regular exercise, but accessibility to exercise programs for this unique population is lacking. We assessed the efficacy of a home-based exercise program on a broad range of indices of physical function, quality of...
Smolander, Jessica Bruchfeld, Annette
Published in
Kidney and Blood Pressure Research
Background: The COVID-19 outbreak has been associated with a high morbidity, mortality, and a risk of long-term sequelae, and patients with severe COVID-19 are at increased risk of acute kidney injury. CKD patients are at high risk of being exposed to COVID-19 and suffer complications and poor outcome. In Sweden, mitigation strategies did not inclu...
Galuška, David Pácal, Lukáš Kaňková, Kateřina
Published in
Kidney and Blood Pressure Research
Background: Vitamin D is a hormone regulating not only calcium and phosphate homeostasis but also, at the same time, exerting many other extraskeletal functions via genomic effects (gene transcription) and probably by non-genomic effects as well. Availability is ensured by dietary intake of its precursors and by de novo production via sunlight. Yet...
