Escalona-Rivano, Rodrigo Chiarello, Delia I Carvajal, Lorena Carrasco-Wong, Ivo Gutiérrez, Jaime A
Published in
Journal of visualized experiments : JoVE
During placenta development, extravillous trophoblast (EVT) cells invade the maternal decidua to remodel the uterine spiral arteries by a process of mesenchymal to endothelial-like transition. Traditionally, this process is evaluated by an in vitro tube-formation assay, where the cells organize themselves into tube-like structures when seeded over ...
Song, Zhuo Zhao, Lisha Hu, Jingwen Zheng, Xi Liu, Yingyu Wang, Hao Chen, Xiaoyan
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Journal of visualized experiments : JoVE
Embryo implantation is affected by the interactions among different cell types in the mother-embryo interface. The direct and indirect communications between various cell types within the decidua are crucial for regulating endometrial receptivity; however, the molecular mechanisms mediating this interaction are still unclear. In this regard, a mode...
Pereira-Rosa, Alexander Oliveira, Thamires S Ferreira, Matheus S Vianna-Barbosa, Rodrigo J Wilmart-Gonçalves, Tula C Ortiga, Tânia M Bloise, Flavia F
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Journal of visualized experiments : JoVE
Skeletal muscle size, mass, and composition are critical properties for studying metabolic and muscle-related diseases, as they directly impact the understanding of disease progression and treatment outcomes. Quantifying a live animal's lean, adipose, and skeletal mass is important in metabolic, physiology, pharmacologic, and geroscience studies. H...
Zhang, Zhenhao Dong, YiBo Xie, YiZhou Yang, HanXiang Fan, Xiaohong Yu, Yang
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Journal of visualized experiments : JoVE
Cauda equina herniation (CEH) is a relatively rare and severe perioperative complication that may occur after lumbar spine surgery. Here, we present a case report of a 36-year-old female patient who experienced CEH after an endoscopic L5-S1 laminectomy and discectomy. The patient presented with right L5-S1 radiculopathy that correlated with finding...
Sawamura, Masanori Takahashi, Ryosuke
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Journal of visualized experiments : JoVE
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the presence of Lewy bodies, which are aggregates of α-synuclein (α-Syn). Recently, the disease was proposed to develop and progress through the prion-like propagation of α-Syn aggregates from the olfactory bulb (OB) or dorsal nucleus of the vagus nerve. Although the origin o...
Martins, Laura Wong, Ramy Larabee, Fredrick J Grillo-Hill, Bree K
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Journal of visualized experiments : JoVE
The Drosophila compound eye is a precisely patterned tissue that has revealed molecular mechanisms and biological processes that drive morphogenesis. It is a simple structure of repeating unit eyes, termed ommatidia, that is used to characterize genetic interactions and gene functions. Mutations that affect eye architecture can be easily detected a...
Ogawa, Joji Dodo, Yusuke Komuro, Yoshihisa Hayakawa, Chikara Okano, Ichiro
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Journal of visualized experiments : JoVE
Thoracolumbar (TL) burst fracture is one of the most common indications for minimally invasive percutaneous pedicle screw fixation. Although the indication for surgical treatment of neurologically intact TL fractures remains under debate, studies have demonstrated that posttraumatic malalignment may lead to a deterioration in the patient's quality ...
Zhu, Ziyue Wang, Lei A Kern, Ryan Pan, Jen Q
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Journal of visualized experiments : JoVE
Sleep stage scoring in rodents is the process of identifying the three stages: nonrapid eye movement sleep (NREM), rapid eye movement sleep (REM), and wake. Sleep stage scoring is crucial for studying sleep stage-specific measures and effects. Sleep patterns in rodents differ from those in humans, characterized by shorter episodes of NREM and REM i...
Mihalko, Emily Abdullah, Abiha Hoteit, Lara Akinbode, David Shea, Susan Neal, Matthew D
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Journal of visualized experiments : JoVE
Microfluidics incorporate physiologically relevant substrates and flows that mimic the vasculature and are, therefore, a valuable tool for studying aspects of thrombosis and hemostasis. At high-shear environments simulating arterial flow, a microfluidic assay facilitates the study of platelet function, as platelet-rich thrombi form in a localized s...
Pan, Yun Chen, Xiao-Li Tan, Na Chen, Ai-Jun
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Journal of visualized experiments : JoVE
Warts, benign epidermal proliferations, are a direct result of human papillomavirus (HPV) infection, specifically targeting the keratinocytes within the stratum corneum of the skin. The development of warts is the most common clinical manifestation of HPV, with plantar warts, condylomata acuminata, and common warts being the most frequently observe...