Yim, H J Kim, I H Suh, S J Jung, Y K Kim, J H Seo, Y S Yeon, J E Kim, C W Kwon, S Y Park, S H
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Published in
Journal of viral hepatitis
Entecavir 0.5 mg (ETV) is widely used among treatment-naïve chronic hepatitis B (CHB) patients. However, 10%-30% of patients show partial virologic response (PVR) to the drug. If the hepatitis B virus (HBV) continues to replicate, the underlying liver disease may progress. Herein, we compared the efficacy of switching to tenofovir disoproxil fumara...
Wang, C-S Chang, T-T Yao, W-J Wang, S-T Chou, P
Published in
Journal of viral hepatitis
Smoking may be a risk factor for diabetes, and it has been suggested that viral hepatitis may predispose to diabetes. We studied diabetes and smoking histories in people with viral hepatitis. From 1997 to 2004, we studied the risk of incident diabetes in a community cohort with hyperendemic HBV and HCV infection in southern Taiwan. The cohort invol...
de Groen, R A Groothuismink, Z M A van Oord, G Kootstra, N A Janssen, H L A Prins, M Schinkel, J Boonstra, A
Published in
Journal of viral hepatitis
Natural killer (NK) cells have long been thought of as a purely innate immune cell population, but increasing reports have described developmental and functional qualities of NK cells that are commonly associated with cells of the adaptive immune system. Of these features, the ability of NK cells to acquire functional qualities associated with immu...
Hlaing, N K T Mitrani, R A Aung, S T Phyo, W W Serper, M Kyaw, A M M Bwa, A H Win, K M Reddy, K R
Published in
Journal of viral hepatitis
DAA therapy ±PEG-IFN achieved high SVR rates. Genotype 6 patients had a low SVR to 12 weeks of LDV and SOF raising the need for other regimens, RBV or longer treatment duration in this population.
Mgaieth, S Kemp, W Gow, P Fink, M Lubel, J Nicoll, A Gazzola, A Hong, T Ryan, M Knight, V
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Published in
Journal of viral hepatitis
While HBV and HCV are risk factors for HCC, uncertainty exists as to whether these viral infections have prognostic significance in HCC. Thus, we compared the overall survival of patients with HBV, HCV and nonviral HCC, and evaluated whether the presence of HBV and HCV predicts patient outcomes. We conducted a multicentre study of HCC cases diagnos...
Bielen, R Moreno, C Van Vlierberghe, H Bourgeois, S Mulkay, J-P Vanwolleghem, T Verlinden, W Brixco, C Decaestecker, J de Galocsy, C
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Published in
Journal of viral hepatitis
Recently, concerns were raised of high rates of HCC recurrence in patients treated with direct-acting antivirals (DAA) for hepatitis C infection. We investigated the HCC occurrence and recurrence rates within 6 months after treatment with DAA with or without pegylated interferon (PEG-IFN) in real life. This is a retrospective, multicenter cohort tr...
Sharma, S Kumar, A Kar, P Agarwal, S Ramji, S Husain, S A Prasad, S Sharma, S
Published in
Journal of viral hepatitis
Hepatitis E virus (HEV) infection can be vertically transmitted, but the factors that transmit the disease to foetuses are still unclear. We studied a total of 144 pregnant women with HEV infection. Cord blood and newborn samples were taken for analysis. Nutritional factors were evaluated on the basis of anthropometric parameters and biochemical fa...
Campana, B Calabrese, D Matter, M S Terracciano, L M Wieland, S F Heim, M H
Published in
Journal of viral hepatitis
Steatosis is a frequent histological feature of hepatitis C virus (HCV) infection. Cohort studies of patients with chronic hepatitis C identified HCV genotype 3 (HCV GT3) as the prevalent steatotic genotype. Moreover, Huh-7 cells over-expressing HCV GT3 core protein accumulate more triglyceride in larger lipid droplets than cells expressing core pr...
Saludes, V Folch, C Morales-Carmona, A Ferrer, L Fernández, L Muñoz, R Jiménez, M Loureiro, E Fernández-Dávila, P Bascuñana, E
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Published in
Journal of viral hepatitis
Alternative strategies are required to enhance the diagnosis of silent hepatitis C virus (HCV) infections in hard-to-reach key populations at risk. Among them, HCV prevalence and bio-behavioural data is scarce for HIV-negative men who have sex with men (MSM) and men and trans-women sex workers. We sought to describe and assess the potential benefit...
Younossi, Zobair M Chan, Henry Lik Yuen Dan, Yock Young Lee, Mei Hsuan Lim, Young-Suk Kruger, Eliza Tan, Seng Chuen
Published in
Journal of viral hepatitis
Chronic, untreated hepatitis C virus (HCV) infection is associated with a poor clinical prognosis and a detrimental impact on patients' lives, including on work productivity. To estimate the value of productivity losses due to genotype 1 (GT1) HCV infection in Hong Kong, Singapore, South Korea and Taiwan and to estimate the potential productivity g...
