Published in Journal of the Royal Society, Interface
Human societies are organized and developed through collective cooperative behaviours. Based on the information in their environment, individuals can form collective cooperation by strategically changing unfavourable surroundings and imitating superior behaviours. However, facing the rampant proliferation and spreading of misinformation, we still l...
Published in Journal of the Royal Society, Interface
Flapping wings may encounter or 'capture' the wake from previous half-stroke, leading to local changes in the instantaneous aerodynamic force on the wing at the start of each half-stroke. In this paper, I developed a simple approach to integrating prediction of these wake capture effects into existing analytical quasi-steady models for hovering ins...
Published in Journal of the Royal Society, Interface
Social and spatial network analysis is an important approach for investigating infectious disease transmission, especially for pathogens transmitted directly between individuals or via environmental reservoirs. Given the diversity of ways to construct networks, however, it remains unclear how well networks constructed from different data types effe...
Published in Journal of the Royal Society, Interface
Mineralized collagen fibrils (MCFs) comprise collagen molecules and hydroxyapatite (HAp) crystals and are considered universal building blocks of bone tissue, across different bone types and species. In this study, we developed a coarse-grained molecular dynamics (CGMD) framework to investigate the role of mineral arrangement on the load-deformatio...
Published in Journal of the Royal Society, Interface
Methicillin-resistant Staphylococcus aureus (MRSA) can colonize multiple body sites, and carriage is a risk factor for infection. Successful decolonization protocols reduce disease incidence; however, multiple protocols exist, comprising diverse therapies targeting multiple body sites, and the optimal protocol is unclear. Standard methods cannot in...
Published in Journal of the Royal Society, Interface
We consider the maintenance of 'product' cell populations from 'progenitor' cells via a sequence of one or more cell types, or compartments, where each cell's fate is chosen stochastically. If there is only one compartment then large amplification, that is, a large ratio of product cells to progenitors comes with disadvantages. The product cell pop...
Published in Journal of the Royal Society, Interface
In the brain, spiking patterns live in a high-dimensional space of neurons and time. Thus, determining the intrinsic structure of this space presents a theoretical and experimental challenge. To address this challenge, we introduce a new framework for applying topological data analysis (TDA) to spike train data and use it to determine the geometry ...
Published in Journal of the Royal Society, Interface
We model the environment of eukaryotic nuclei by representing macromolecules by only their entropic properties, with globular molecules represented by spherical colloids and flexible molecules by polymers. We put particular focus on proteins with both globular and intrinsically disordered regions, which we represent with 'tadpole' constructed by gr...
Published in Journal of the Royal Society, Interface
In applied biotremology, vibrational signals or cues are exploited to manipulate the target species behaviour. To develop an efficient pest control strategy, other than a detailed investigation into the pest biology and behaviour, the role of the substrate used to transmit the signal is an important feature to be considered, since it may affect vib...
Published in Journal of the Royal Society, Interface
DNA methylation occurs predominantly on cytosine-phosphate-guanine (CpG) dinucleotides in the mammalian genome, and the methylation landscape is maintained over mitotic cell division. It has been posited that coupling of maintenance methylation activity among neighbouring CpGs is critical to stability over cellular generations; however, the mechani...
