Neurosarcoidosis and multiple intracerebral hematomas: An unusual clinical presentation.
Published in Journal of the neurological sciences
The wide spectrum of clinical phenotypes of spinal muscular atrophy with respiratory distress type 1: A systematic revie...
Published in Journal of the Neurological Sciences
Abstract Spinal muscular atrophy with respiratory distress type 1 (SMARD1), also known as distal spinal–muscular atrophy 1 (DSMA10), is an autosomal recessive type of spinal muscular atrophy that is related to mutations in the IGHMBP2 gene, which encodes for the immunoglobulin μ-binding protein. SMARD1 patients usually present low birth weight, dia...
Dynamical intrinsic functional architecture of the brain during absence seizures.
...Published in Brain structure & function
Epilepsy is characterized by recurrent and temporary brain dysfunction due to discharges of interconnected groups of neurons. The brain of epilepsy patients has a dynamic bifurcation that switches between epileptic and normal states. The dysfunctional state involves large-scale brain networks. It is very important to understand the network mechanis...
Automated gait and balance parameters diagnose and correlate with severity in Parkinson disease
Published in Journal of the Neurological Sciences
Abstract Objective To assess the suitability of instrumented gait and balance measures for diagnosis and estimation of disease severity in PD. Methods Each subject performed iTUG (instrumented Timed-Up-and-Go) and iSway (instrumented Sway) using the APDM® Mobility Lab. MDS-UPDRS parts II and III, a postural instability and gait disorder (PIGD) scor...
Primary neurolymphomatosis diagnosis and treatment: A retrospective study
Published in Journal of the Neurological Sciences
Abstract Background To discuss the therapeutic approach for primary neurolymphomatosis. Methods We report all primary neurolymphomatosis cases referred to our institution, with descriptions of clinical, radiological, electrophysiological, histological features and long-term follow-up. We treated all patients with a combination of high-dose methotre...
Prevalence of migraine headache and its weight on neurological burden in Africa: A 43-year systematic review and meta-an...
Published in Journal of the Neurological Sciences
Abstract Background Headache burden is not adequately explored in Africa. Here, we measured weighted migraine prevalence from community-based studies in Africa. Methods PubMed search was employed using terms ‘headache in Africa’ AND/OR ‘migraine in Africa’ for published literature from 1970 until January 31, 2014. PRISMA was applied for systematic ...
Tapered withdrawal of phenytoin removes protective effect in EAE without inflammatory rebound and mortality.
Published in Journal of the neurological sciences
Axon degeneration has been identified as a major contributor to non-remitting neurological deficits in patients with multiple sclerosis (MS), which has elicited substantial interest in the development of neuroprotective therapies. Sodium channel blockers, including phenytoin, carbamazepine, flecainide and lamotrigine, have been shown to protect axo...
Double trouble? Progranulin mutation and C9ORF72 repeat expansion in a case of primary non-fluent aphasia.
...Published in Journal of the neurological sciences
Resolution of unilateral obstructive hydrocephalus complicating expanding thrombosed basilar apex aneurysm after anticoa...
...Published in Journal of the neurological sciences
Could immediate blood pressure reduction after acute ischemic stroke prevent early recurrent strokes?
Published in Journal of the neurological sciences
