Ronald, Angelica de Bode, Nora Polderman, Tinca J C
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
To investigate, by systematically reviewing the literature, whether the attention-deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) associates with ADHD and related traits in independent clinical and population samples. PubMed, Embase and PsychoInfo were systematically searched, alongside study bibliographies. Quality assessments wer...
Lu, Lu Mills, Jeffrey A Li, Hailong Schroeder, Heidi K Mossman, Sarah A Varney, Sara T Cecil, Kim M Huang, Xiaoqi Gong, Qiyong Ramsey, Laura B
...
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
Amygdala-ventrolateral prefrontal cortex (VLPFC) circuitry is disrupted in pediatric anxiety disorders, yet how selective serotonin reuptake inhibitors (SSRIs) affect this circuitry is unknown. We examined the impact of the SSRI escitalopram on functional connectivity (FC) within this circuit, and whether early FC changes predicted treatment respon...
Taylor, Brittany K Eastman, Jacob A Frenzel, Michaela R Embury, Christine M Wang, Yu-Ping Stephen, Julia M Calhoun, Vince D Badura-Brack, Amy S Wilson, Tony W
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
Adolescence is a sensitive period for the development and emergence of anxiety and mood disorders. Research suggests that symptoms ranging from subclinical to clinical levels are associated with pathological developmental changes in the neocortex. However, much of this research has been cross-sectional, limiting the field's ability to identify the ...
Jonassen, Rune
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
There is a pressing need to improve treatment, and clinical trials should not only focus on efficacy, but also on identifying the underlying mechanisms through which treatments operate.1 Treatment with a serotonergic antidepressant is commonly used to treat pediatric anxiety disorders, including generalized anxiety disorder (GAD). Serotonergic anti...
Mathieu, Sharna L Uddin, Riaz Brady, Morgan Batchelor, Samantha Ross, Victoria Spence, Susan H Watling, David Kõlves, Kairi
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
Helplines are generally a population-level resource for providing free, timely, easy-to-access, and anonymous counseling and/or information. Helplines have been developed and widely implemented for specific use by young people. The current study aimed to systematically review the literature to determine the status of research into the use of helpli...
Hitchcock, Caitlin Goodall, Benjamin Sharples, Olivia Meiser-Stedman, Richard Watson, Peter Ford, Tamsin Dalgleish, Tim
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
Posttraumatic stress disorder (PTSD) is a debilitating condition that when left untreated can have severe lifelong consequences for psychological, social, and occupational functioning. Initial conceptualizations of PTSD were centered on adult presentations. However, the instantiation of developmentally appropriate PTSD in young children (PTSD-YC) c...
Zeytinoglu, Selin Morales, Santiago Lorenzo, Nicole E Chronis-Tuscano, Andrea Degnan, Kathryn A Almas, Alisa N Henderson, Heather Pine, Daniel S Fox, Nathan A
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
The COVID-19 pandemic has brought unprecedented changes to young adults' lives, resulting in mental health difficulties for many; however, some individuals are particularly prone to heightened anxiety. Little is known about the early life predictors of anxiety during the pandemic. We examined a developmental pathway from behavioral inhibition (BI),...
Pérez-Edgar, Koraly
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
Bronfenbrenner's ecological systems theory1 argued that the historical context of development, the chronosystem, can have as large an impact on the course and tenor of development as the closely tethered microsystem of family, neighborhood, and school that we typically focus on in the laboratory and in the clinic. While we often speak of these nest...
Ramchand, Rajeev
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
In Mathieu and colleagues'1 recent systematic review, the authors present important research insights about young people who call hotlines, why they call them, the types of services that callers receive, and the quality of this care. Albeit important on its own, it is particularly timely for American practitioners and policymakers. In December 2020...
Moeller, Karen E. Meeks, Matie Reynoldson, Jill Douglass, Michell
Published in
Journal of the American Academy of Child and Adolescent Psychiatry
Increasing coronavirus disease 2019 (COVID-19) vaccination rates has been identified by the U.S. Centers of Disease Control and Prevention as critical to ending the COVID-19 pandemic.1 On May 10, 2021, the Pfizer-BioNTech COVID-19 vaccine (BNT162b2; Pfizer, Inc., New York, New York, and BioNTech SE, Mainz, Germany) was approved for emergency use au...
