Masilela, Charity Pearce, Brendon Ongole, Joven Jebio Adeniyi, Oladele Vincent Benjeddou, Mongi
Published in
Journal of personalized medicine
This study described single nucleotide polymorphisms (SNPs) in hydrochlorothiazide-associated genes and further assessed their correlation with blood pressure control among South African adults living with hypertension. A total of 291 participants belonging to the Nguni tribes of South Africa on treatment for hypertension were recruited. Nineteen S...
Zadeh Shirazi, Amin Fornaciari, Eric McDonnell, Mark D Yaghoobi, Mahdi Cevallos, Yesenia Tello-Oquendo, Luis Inca, Deysi Gomez, Guillermo A
Published in
Journal of personalized medicine
In recent years, improved deep learning techniques have been applied to biomedical image processing for the classification and segmentation of different tumors based on magnetic resonance imaging (MRI) and histopathological imaging (H&E) clinical information. Deep Convolutional Neural Networks (DCNNs) architectures include tens to hundreds of proce...
Grigoriadou, Georgia Ι Esagian, Stepan M Ryu, Han Suk Nikas, Ilias P
Published in
Journal of personalized medicine
Malignant pleural effusions (MPEs) often develop in advanced cancer patients and confer significant morbidity and mortality. In this review, we evaluated whether molecular profiling of MPEs with next generation sequencing (NGS) could have a role in cancer management, focusing on lung cancer. We reviewed and compared the diagnostic performance of pl...
Sutton, Erica J Beck, Annika T Gamm, Kylie O McCormick, Jennifer B Kullo, Iftikhar J Sharp, Richard R
Published in
Journal of personalized medicine
As applications of genomic sequencing have expanded, offering genetic counseling support to all patients is arguably no longer practical. Additionally, whether individuals desire and value genetic counseling services for genomic screening is unclear. We offered elective genetic counseling to 5110 individuals prior to undergoing sequencing and 2310 ...
Harte, Richard Quinlan, Leo R Glynn, Liam Rodriguez-Molinero, Alejandro Scharf, Thomas Carenas, Carlos Reixach, Elisenda Garcia, Joan Carrabina, Jordi ÓLaighin, Gearóid
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Published in
Journal of personalized medicine
Wearable electronics are gaining widespread use as enabling technologies, monitoring human physical activity and behavior as part of connected health infrastructures. Attention to human factors and comfort of these devices can greatly positively influence user experience, with a subsequently higher likelihood of user acceptance and lower levels of ...
Ostby, Pamela L Armer, Jane M
Published in
Journal of personalized medicine
Breast cancer survivors are at increased risk for breast cancer-related lymphedema (BCRL), a chronic, debilitating, condition that is progressive and requires lifelong self-management. Up to 40% of 3 million breast cancer survivors in the US will develop BCRL, which has no cure, is irreversible, and requires self-management with regimens that may i...
Parisot, John P Thorne, Heather Fellowes, Andrew Doig, Ken Lucas, Mark McNeil, John J Doble, Brett Dobrovic, Alexander John, Thomas James, Paul A
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Published in
Journal of personalized medicine
"Cancer 2015" is a longitudinal and prospective cohort. It is a phased study whose aim was to pilot recruiting 1000 patients during phase 1 to establish the feasibility of providing a population-based genomics cohort. Newly diagnosed adult patients with solid cancers, with residual tumour material for molecular genomics testing, were recruited into...
Tidhar, Dorit Armer, Jane M Deutscher, Daniel Shyu, Chi-Ren Azuri, Josef Madsen, Richard
Published in
Journal of personalized medicine
Understanding whether a true change has occurred during the process of care is of utmost importance in lymphedema management secondary to cancer treatments. Decisions about when to order a garment, start an exercise program, and begin or end therapy are based primarily on measurements of limb volume, based on circumferences taken by physiotherapist...
Fu, Mei R Axelrod, Deborah Guth, Amber A Fletcher, Jason Qiu, Jeanna M Scagliola, Joan Kleinman, Robin Ryan, Caitlin E Chan, Nicholas Haber, Judith
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Published in
Journal of personalized medicine
Obesity is one of the risk factors for developing lymphedema following breast cancer treatment. We prospectively enrolled 140 women and followed the participants for 12 months after surgery to investigate patterns of obesity and lymph fluid level in the first year of cancer treatment. Electrical bioimpedance devices were used to measure weight, BMI...
Chance-Hetzler, Janet Armer, Jane Van Loo, Maggie Anderson, Blake Harris, Robin Ewing, Rebecca Stewart, Bob
Published in
Journal of personalized medicine
The potential impact of breast cancer-related lymphedema (LE) is quite extensive, yet it often remains under-diagnosed until the later stages. This project examines the effectiveness of prospective surveillance in post-surgical breast cancer patients. A retrospective analysis of 49 out of 100 patients enrolled in a longitudinal prospective study at...
