Masuda, Keisuke Shigematsu, Hideki Maeda, Manabu Okuda, Akinori Tanaka, Yasuhito
Published in
Journal of orthopaedic surgery and research
Several methods can be used to diagnose discogenic pain, but only discoblock can diagnose discogenic pain definitively. This study aimed to examine the usefulness of an ultrasound-guided disc pain induction test for a simple and accurate diagnosis of the culprit lesion. We included 41 patients with lumbar pain in whom pain was induced by an ultraso...
Hong, Hao Li, Jun Ding, Haoyang Deng, Yi Deng, Zhongliang Jiang, Qilong
Published in
Journal of orthopaedic surgery and research
The unilaterally extrapedicular approach is adopted increasingly to perform balloon kyphoplasty in treating osteoporotic lumbar fractures, which is intended to improve radiological and clinical efficacy. We compared the efficacy and safety of this method with a unilaterally transpedicular approach. We conducted a single-center, randomized controlle...
Huang, Jie Lian, Shi-Lin Han, Jia-Heng Lu, Zheng-Cao Ding, Yu
Published in
Journal of orthopaedic surgery and research
Intervertebral disk degeneration (IVDD) can be effectively treated using platelet-rich plasma (PRP). While the exact process is fully understood, it is believed that using pure PRP (P-PRP) without leukocytes is a better option for preventing IVDD. Semaphorin-3A (Sema3A), an inhibitor of angiogenesis and innervation, is essential for preserving IVDD...
Kim, Young Mo Joo, Yong Bum Park, Young Cheol Lee, Seung-Ho Song, Ju-Ho
Published in
Journal of orthopaedic surgery and research
Accurate correction is a prerequisite for the favorable outcomes of open-wedge high tibial osteotomy (OWHTO). However, previous studies have reported disappointing results regarding correction accuracy despite the use of intra-operative navigation, which implies that a certain factor other than bony components is involved in the inaccurate correcti...
Zhang, Zhuangzhuang Zhang, Fukang Yang, Xin Fan, Hua Cheng, Qinghao Guo, Hongzhang
Published in
Journal of orthopaedic surgery and research
To systematically evaluate the clinical safety and efficacy of the direct superior approach and the conventional surgical approach. From PubMed, Embase, the Cochrane Library, and China Knowledge Network up to January 30, 2023. A total of 7 case series involving 4306 patients undergoing total hip arthroplasty were included, including 679 patients wi...
Sui, Jie Dai, Fei Shi, Jiusheng Zhou, Changcheng
Published in
Journal of orthopaedic surgery and research
Several members of the ubiquitin-specific proteases (USPs) family have been revealed to regulate the progression of osteoarthritis (OA). The current study aimed to investigate the role and the underlying mechanism of USP25 in IL-1β-induced chondrocytes and OA rat model. It was discovered that IL-1β stimulation upregulated USP25, increased ROS level...
Sun, Silu Tao, Simin Xi, Xiaoyan Jiang, Tao Zhu, Qian Zhou, Yan Li, Hui
Published in
Journal of orthopaedic surgery and research
Malnutrition is recognized as a risk factor for osteoporosis and T2DM. Previous studies have demonstrated the relationship between nutritional assessment tools and BMD. However, few studies have compared the effects of three nutritional risk assessment tools (GNRI, CONUT, and PNI). This study aimed to investigate the correlation between three nutri...
Yang, Lei Li, Wenhao Yang, Yongdong Zhao, He Yu, Xing
Published in
Journal of orthopaedic surgery and research
This study aimed to investigate the correlation between the MRI high-intensity zone (HIZ) and the pathogenesis of discogenic low back pain. Literature from PubMed, EMBASE, Cochrane Library, Science Direct, China Knowledge Network, Wanfang Database, and China Biomedical Literature Database was searched until August 2023. Cohort studies including pat...
Luan, Zhiwei Wang, Yansong
Published in
Journal of orthopaedic surgery and research
N6-methyl adenosine (m6A) is the most common reversible mRNA modification in eukaryotes implicated in key roles in various biological processes. The purpose of our analysis was to examine the association of ankylosing spondylitis (AS) with m6A methylation. We obtained 72 samples from the data set GSE73754, including 52 AS patients and 20 healthy pe...
Xiao, Fangjun Wei, Tengfei Xiao, Huan He, Wei Wei, Qiushi
Published in
Journal of orthopaedic surgery and research
Osteonecrosis of the femoral head (ONFH) is becoming a prevalent global health problem. 4-Hydroxynonenal (4-HNE) serves as a common marker of oxidative stress. This study aims to study the potential role of 4-HNE in the progression of steroid-induced osteonecrosis of the femoral head (SIONFH). Between April 2021 and December 2021, 64 subjects were ...
