Reduction of radiation exposure in spinal surgery.
Published in Journal of neurosurgical sciences
Accuracy of percutaneous pedicle screws for thoracic and lumbar spine fractures compared with open technique.
Published in Journal of neurosurgical sciences
This study aimed to compare the accuracy of screw placement between open pedicle screw fixation and percutaneous pedicle screw fixation (MIS) for the treatment of thoracolumbar spine fractures (TSF). forty-nine patients with acute TSF who were treated with transpedicular screw fixation from January 2013 to December 2016 were retrospectively reviewe...
Incidence and risk factors of neurosurgical site infections: results of a prospective multicenter cohort study on 6359 s...
Published in Journal of neurosurgical sciences
Neurosurgical surgical site infections (SSI) are life-threatening complications, requiring medical treatment and additional surgeries and remain a substantial cause of morbidity. In order to identify the incidence and the main risk factors for SSI, we developed the Prophylaxis with Antibiotic Protocol for Neurosurgical Site Infections Study (PASSIS...
Application of PHASES and ELAPSS scores to ruptured cerebral aneurysms: how many would have been conservatively managed?...
Published in Journal of neurosurgical sciences
We calculated the PHASES and ELAPSS scores for a large cohort of ruptured intracranial aneurysms (RIA) in order to determine whether these RIA would have been pre-emptively treated or closely followed-up should they have been detected prior to rupture. We retrospectively reviewed a consecutive series of RIA over a 20-year period. The primary outcom...
Molecular and radiological characterization of glioblastoma multiforme using magnetic resonance imaging.
...Published in Journal of neurosurgical sciences
Glioblastoma multiforme (GBM) is the most malignant, aggressive and common form of primary brain cancer. Currently, GBM is considered to be a homogenous mass as all its margins are treated equally at the time of resection. However, it is not known whether radiologically distinct regions of GBM are also distinct at molecular level. We conducted this...
Blood-tissue analysis of TP53 polymorphisms and survival of patients with glioma.
Published in Journal of neurosurgical sciences
The role of single nucleotide polymorphisms (SNPs) in TP53 in the pathogenesis of glioma is still debated. The aim of our study was to investigate the role of several TP53 SNPs in the risk of glioma and their possible role as prognostic biomarkers of overall and progression-free survival. We examined 12 SNPs in TP53 from peripheral blood and neopla...
Isoflurane improves cerebral ischemia-reperfusion injury in rats via activating MAPK signaling pathway.
Published in Journal of neurosurgical sciences
Artificial neural network predicts hemorrhagic contusions following decompressive craniotomy in traumatic brain injury.
Published in Journal of neurosurgical sciences
This study aimed to explore relevant factors of hemorrhagic contusions following decompressive craniotomy (DC) in traumatic brain injury (TBI) and create an artificial neural network (ANN) prediction model of the risk factors of hemorrhagic contusions. This study analyzed 425 patients with TBI who underwent DC in the Neurosurgery Department of Shao...
Shifting from the directly observation via eyepiece lens to the monitor viewing of the surgical field: a new era for the...
Published in Journal of neurosurgical sciences
Prognostic factors in chronic subdural hematoma: results from a monocentric consecutive surgical series of 605 patients....
Published in Journal of neurosurgical sciences
The study of age-related diseases like chronic subdural hematoma (CSDH) is of high interest, considered the general ageing of the population. This investigation aimed to identify the main clinical characteristics of CSDH patients, to evaluate the impact of the disease on quality of life, its treatment and comorbidities/complications and to compare ...
