Dick, Katherine Briggs, Andrew Ohsfeldt, Robert Sydendal Grand, Tobias Buchs, Sarah
Published in
Journal of medical economics
Aims: Allergic rhinitis is caused by sensitivity to environmental allergens that can significantly impact quality-of-life. The objective of this analysis was to estimate health state utilities and quality-adjusted life days (QALDs) for a tree allergy immunotherapy trial, TT-04 (EudraCT No.2015-004821-15). Health-state utilities are a measure of pat...
Ueno, Fumiaki Doi, Michio Kawai, Yumi Ukawa, Naoto Cammarota, Jordan Betts, Keith A
Published in
Journal of medical economics
Aims: Adalimumab, infliximab, and ustekinumab have been approved for patients with moderate-to-severe Crohn's disease in Japan. This study compared the relative efficacy and cost-effectiveness of adalimumab, infliximab, and ustekinumab in patients with Crohn's disease based on data from randomized controlled trials.Methods: Data were extracted from...
Floros, Lefteris Pagliuca, Antonio Taie, Amer Al Weidlich, Diana Rita Capparella, Maria Georgallis, Mihalina Sung, Anita Hor-Yun
Published in
Journal of medical economics
Aims: To estimate the cost-effectiveness of isavuconazole compared with the standard of care, voriconazole, for the treatment of patients with invasive fungal infection disease when differential diagnosis of the causative pathogen has not yet been achieved at treatment initiation.Materials and methods: The economic model was developed from the pers...
Joseph, Richard W Shillington, Alicia C Lee, Todd A Macahilig, Cynthia P Diede, Scott J Dave, Vaidehi Harshaw, Qing Scherrer, Emilie Liu, Frank Xiaoqing
Published in
Journal of medical economics
Background: Both pembrolizumab (PEMBRO) and ipilimumab + nivolumab (IPI + NIVO) are FDA-approved immunotherapy regimens for advanced melanoma (AM). Each regimen has different toxicity profiles potentially impacting healthcare resource utilization (HCRU). This study compared real-world hospitalization and emergency department (ED) utilization within...
Cai, Qian Teeple, Amanda Wu, Bingcao Muser, Erik
Published in
Journal of medical economics
Objective: To describe the prevalence and costs of anxiety and depression among moderate-to-severe psoriasis (PsO) patients in a commercially-insured US population.Methods: The IBM MarketScan Commercial database was used to select adults with moderate-to-severe PsO (≥1 PsO diagnosis and ≥1 systemic or biologic medication) within each calendar year ...
Berdugo, Mauricio A Kirson, Noam Y Zimmer, Louise Beyhaghi, Hadi Toback, Seth Scarpati, Lauren M Stone, Michael N Dember, Ross Tseng-Tham, Joshua Wen, Jody
...
Published in
Journal of medical economics
Purpose: To evaluate the budget impact of adding a diagnostic test of tissue inhibitor of metalloproteinase 2 and insulin-like growth factor binding protein 7 ([TIMP-2]·[IGFBP7]), which identifies patients at risk of moderate-to-severe acute kidney injury (AKI), to the current standard of care (SOC) in a hospital setting.Materials and methods: A bu...
Teeple, Amanda Muser, Erik
Published in
Journal of medical economics
Aims: To estimate annual cost per response (CPR) in the US and number needed to treat (NNT) among patients receiving guselkumab or adalimumab treatment for moderate-to-severe plaque psoriasis (PsO).Materials and methods: Results from VOYAGE 1, a double-blind, placebo-controlled, head-to-head, 48-week study of guselkumab compared with adalimumab in ...
Shih, Tiffany M Sail, Kavita R Jalundhwala, Yash J Sullivan, Jeffrey van Eijndhoven, Emma Zadikoff, Cindy Marshall, Thomas S Lakdawalla, Darius N
Published in
Journal of medical economics
Aims: To estimate the relationship between functional status (FS) impairment and nursing home admission (NHA) risk in Parkinson's disease (PD) patients, and quantify the effect of advanced PD (APD) treatment on NHA risk relative to standard of care (SoC).Materials and methods: PD patients were identified in the Medicare Current Beneficiary Survey (...
Annemans, Lieven
Published in
Journal of medical economics
Moore Simas, Tiffany A Huang, Ming-Yi Packnett, Elizabeth R Zimmerman, Nicole M Moynihan, Meghan Eldar-Lissai, Adi
Published in
Journal of medical economics
Objective: To assess healthcare resource utilization (HRU) and costs in children of mothers with and without postpartum depression (PPD).Methods: Administrative claims data from the IBM Watson Health MarketScan Databases (2010-2016) were used. Women with live births (index date = delivery date) were identified and linked to their newborns. The moth...
