Cid, Joan Carbassé, Gloria Alba, Cristina Perea, Dolores Lozano, Miquel
Published in
Journal of clinical apheresis
Collection efficiency (CE1) of cells refers to the number of cells that are collected from the total number of cells processed by the apheresis device. Limited data are available about the CE1 of cells when performing leukocytapheresis in nonmobilized donors for cellular therapy purposes. The aim of our study was to evaluate donor- and procedure-re...
Rodríguez-Lago, Iago Benítez, José M Sempere, Laura Sáez-González, Esteban Barreiro-de Acosta, Manuel de Zárate, Jone O Cabriada, José L
Published in
Journal of clinical apheresis
To assess the effectiveness and safety of combining granulocyte-monocyte apheresis (GMA) and vedolizumab (VDZ) in patients with refractory ulcerative colitis (UC). This retrospective, multicentre pilot study included all UC patients receiving both GMA and VDZ. We recorded data on GMA sessions, demographic characteristics, and clinical response. Eff...
Cooling, Laura Thompson, Tina Downs, Terry Abusin, Ghada Yanik, Greg
Published in
Journal of clinical apheresis
Extracorporeal photopheresis (ECP) in young pediatric patients has a risk for procedural hypotension and anemia due to extracorporeal fluid shifts. A standard mitigation policy in these patients is to prime the device with packed red blood cells (RBC) or whole blood. We now report multiple episodes of hemolysis while attempting to prime the Therako...
Garrity, Danielle Graves, Molly Linden, Jeanne St Pierre, Patricia Ducharme, Paula Zhao, Yong Greene, Mindy Vauthrin, Michelle Weinstein, Robert
Published in
Journal of clinical apheresis
We prospectively evaluated the Bard PowerFlow Implantable Apheresis IV Port in four patients undergoing outpatient therapeutic plasma exchange over 18 to 97 days. Three had bilateral internal jugular access ports, and one had a single left internal jugular access port for the inlet line with return via antecubital vein. Two patients receiving 5% al...
Badar, Talha Dhakal, Binod Szabo, Aniko Padmanabhan, Anand Johnson, Bryon D Heidtke, Sarah Esselmann, Jean Chhabra, Saurabh Hamadani, Mehdi Hari, Parameswaran
...
Published in
Journal of clinical apheresis
The use of granulocyte-colony stimulating factor (G-CSF) with or without chemotherapy to mobilize hematopoietic progenitor cells (HPCs) can result in significant morbidity in light chain (AL) amyloidosis patients. Plerixafor, a strong inducer and mobilizer of HPCs, can be used as an adjunct to G-CSF to improve mobilization efficiency. We describe t...
Ali, Salah Chiang, Kuang-Yueh Even-Or, Ehud Di Mola, Maria Schechter, Tal Ali, Muhammad McDougall, Elizabeth Svajger, Gordana Licht, Christoph Krueger, Joerg
...
Published in
Journal of clinical apheresis
Peripheral hematopoietic stem cell (HSC) collections are needed for autologous hematopoietic stem cell transplantation (HSCT). Since 2015, our institution has utilized a secondary chamber mononuclear cell (MNC) protocol on the Spectra Optia apheresis system. Recently, a new continuous mononuclear collection protocol (CMNC) was developed for the sam...
Kuhn, Alexis K Bartoo, Gabriel T Dierkhising, Ross A Mara, Kristin C Winters, Jeffrey L Patnaik, Mrinal M Gastineau, Dennis A Adamski, Jill Merten, Julianna A
Published in
Journal of clinical apheresis
Extracorporeal photopheresis (ECP) is associated with few adverse effects. We have anecdotally noted patients treated with long-term ECP develop iron deficiency anemia (IDA). We performed a retrospective chart review of adult patients who received ECP for any indication at Mayo Clinic Rochester and Mayo Clinic Arizona. The primary objective was to ...
Colavita, Daniela Kim, Haewon C Friedman, David F
Published in
Journal of clinical apheresis
Estimation of the total blood volume (TBV) is fundamental to the control of automated red cell exchange (RCE). Error in the TBV estimate can produce outcomes that deviate from the prescribed targets, and may endanger the patient. Both the Spectra Optia and the COBE Spectra use the Nadler formulae to estimate TBV. There is a potential for large over...
Patale, Dnyaneshwar Bajpai, Meenu Maiwall, Rakhi Kumar, Guresh
Published in
Journal of clinical apheresis
The management of liver failure (LF) remains a challenge for the physician. Therapeutic plasma exchange (TPE) improves consciousness level and tends to normalize hyperkinetic circulation by removing neurotoxic substances from the circulation. Hemodynamic stability is essential for optimal patient management. The objective of this study was to obser...
Irani, Mehraboon S Toushan, Mazen Zhang, Liyun Simpson, Pippa M Karafin, Matthew S
Published in
Journal of clinical apheresis
Partial normal saline replacement during plasma exchange procedures is a common practice to reduce procedure costs but may increase the risk of adverse events, such as hypotension and citrate reactions. The goal of this study was to compare adverse event rates for the patients that used albumin or albumin/saline as replacement. A retrospective char...
