Shan, Peng Tang, Bo Xie, Shanshan Zhang, Zengling Fan, Jiehou Wei, Zheng Song, Chun
Published in
Journal of cellular biochemistry
Newcastle disease virus (NDV) is endowed with the oncolytic ability to kill tumor cells, while rarely causing side effects in normal cells. Both estrogen receptor α (ERα) and the G protein estrogen receptor (GPER) modulate multiple biological activities in response to estrogen, including apoptosis in breast cancer (BC) cells. Here, we investigated ...
Kang, Ji Wan Kim, Youngjoo Lee, Yoonsung Myung, Kyungjae Kim, Yun Hak Oh, Chang-Kyu
Published in
Journal of cellular biochemistry
Acute myeloid leukaemia (AML) is a blood cancer where undifferentiated myeloid cells are increased in the bone marrow and peripheral blood. As AML is dangerous and shows poor prognosis, many researchers categorised the relevant cytogenetic factors according to risk and prognosis. However, the specific reasons for poor cytogenetic factors remain unk...
Su, Dongsheng Ju, Yansong Han, Wei Yang, Yanhua Wang, Fengyun Wang, Tong Tang, Jianmin
Published in
Journal of cellular biochemistry
Diabetic cardiomyopathy can cause cardiac dysfunction and eventually lead to heart failure and sudden death. Long noncoding RNA (lncRNA) Gas5 has been reported to play a function in cardiomyocyte. Here we studied the function of Gas5 on newborn mouse cardiomyocyte (NMC) apoptosis to detect its molecular mechanism. High-glucose treatment was impleme...
Song, Qihan Zhao, Fengli Yao, Jingfan Dai, Hailin Hu, Lei Yu, Shun
Published in
Journal of cellular biochemistry
MicroRNAs (miRs) have been extensively studied for their involvement in multiple sclerosis (MS). We investigated the involvement of miR-134-3p on MS. The MS rat model was established, and positive expression of interleukin-17 (IL-17) was detected using the immunohistochemical method while the expression of miR-134-3p and serine protease 57 (PRSS57)...
Luo, Xi Han, Gang Lu, Renfei Guan, Shaopei Wang, Yifan Ju, Linling Chen, Lin Shao, Jianguo Bian, Zhaolian
Published in
Journal of cellular biochemistry
Several protein-coding genes have been identified to play essential roles in cancer biology, and they are dysregulated in many tumors. Transmembrane protein 106C (TMEM106C) is differentially expressed in several human and porcine diseases; however, the expression and biological functions of TMEM106C in hepatocellular carcinoma (HCC) are not clear. ...
Chen, Shulian Liao, Banghua Jin, Xi Wei, Tangqiang He, Qing Lin, Yifei Ai, Jianzhong Gong, Lina Li, Hong Wang, Kunjie
...
Published in
Journal of cellular biochemistry
Extracellular matrix (ECM) accumulation plays a key role in the progression of bladder outlet obstruction (BOO). Muscarinic receptors have been widely reported to serve as pivotal regulators in lung tissue remodeling. However, the influence of them on human bladder smooth muscle cells (HBSMCs) and the underlying molecular mechanisms have not yet be...
Dong, Caihua Yin, Fuqiang Zhu, Dan Cai, Xiangxue Chen, Cuilan Liu, Xia
Published in
Journal of cellular biochemistry
Drug resistance, an impenetrable barrier in the treatment of ovarian cancer (OC), is often associated with poor outcomes. Hence, it is urgent to discover new factors controlling drug resistance and survival. The association between neurocalcin delta (NCALD) and cancer drug resistance is poorly understood. Here, we reveal that NCALD messenger RNA ex...
Chen, Kaihua Chen, Li Li, Ling Qu, Song Yu, Binbin Sun, Yongchu Wan, Fangzhu Chen, Xishan Liang, Renba Zhu, Xiaodong
...
Published in
Journal of cellular biochemistry
Radioresistance may be induced by cancer stem cells (CSCs), while the biological traits of CSCs need to be retained by telomerase. The telomerase activity mainly depends on the transcriptional regulation of human telomerase reverse transcriptase (hTERT). Moreover, Wnt/β-catenin signaling is also considered essential for maintaining the CSC phenotyp...
Tang, Xiaojiang Zhou, Yuhui Liu, Yang Zhang, Wei Liu, Chao Yan, Changyou
Published in
Journal of cellular biochemistry
As an aggressive breast cancer (BCa) subtype, triple-negative breast cancer (TNBC) responses poorly to chemotherapy and endocrine therapy, and usually has a worse prognosis. This is largely due to the lack of specific therapeutic targets, laying claim to an imperious demand to clarify the key signaling pathways potentiating TNBC progression. Herein...
Liu, Jingfu Li, Zhen Teng, Wenhao Ye, Xianren
Published in
Journal of cellular biochemistry
The connection between circular RNAs (circRNAs) and gastric cancer has been reported widely in recent years. However, previous studies have focused mainly on circRNAs from gastric cancer tissue. The objectives of the present study were to detect dysregulated circRNAs from both tissue and plasma of patients with gastric cancer and to explore their p...
