Xiao, Dongliang Zhou, Quan Gao, Yunbing Cao, Baichuan Zhang, Qiong Zeng, Gaofeng Zong, Shaohui
Published in
Journal of cellular biochemistry
Perturbations in the balanced process of osteoblast-mediated bone formation and osteoclast-mediated bone resorption leading to excessive osteoclast formation and/or activity is the cause of many pathological bone conditions such as osteoporosis. The osteoclast is the only cell in the body capable of resorbing and degrading the mineralized bone matr...
Ozdil, Berrin Güler, Günnur Acikgoz, Eda Kocaturk, Duygu Calik Aktug, Huseyin
Published in
Journal of cellular biochemistry
Embryonic stem cells (ESCs) are promising research materials to investigate cell fate determination since they have the capability to differentiate. Stem cell differentiation has been extensively studied with various microenvironment mimicking structures to modify cellular dynamics associated with the cell-extracellular matrix (ECM) interactions an...
Kong, Lingsuo Wei, Qing Hu, Xianwen Chen, Lanren Li, Juan
Published in
Journal of cellular biochemistry
To detect the expression and identify the role of Ribosomal protein S15A (RPS15A) in human breast cancer (BC). Immunohistochemistry (IHC) was carried out for detecting the levels of RPS15A protein. Quantitative PCR was used to evaluate the mRNA level of RPS15A in one normal breast and three BC cell lines. Lentivirus-mediated shRNA targeting RPS15A ...
Wu, Dong-Mei Zheng, Zi-Hui Fan, Shao-Hua Zhang, Zi-Feng Chen, Gui-Quan Lu, Jun
Published in
Journal of cellular biochemistry
Nuclear factor erythroid 2-related factor 2 (Nrf2) can alleviate diffuse axonal injury (DAI)-induced apoptosis by regulating expression of heme oxygenase-1 (HO-1), while sulforaphane (SFN) was shown to reduce oxidative stress by increasing the expression of Nrf2. Therefore, we aimed to investigate therapeutic effect of SFN in the treatment of DAI a...
Sun, Jin Guo, Ying Bie, Beibei Zhu, Mengchen Tian, Hongwei Tian, Jing Li, Jun Yang, Yi Ji, Fanpu Kong, Guangyao
...
Published in
Journal of cellular biochemistry
Accumulating findings reveal that long noncoding RNAs (lncRNAs) as crucial regulatory molecules serve vital functions in the progression of hepatocellular carcinoma (HCC). This study aims to investigate the biological roles and mechanisms of lncRNA HOXD cluster antisense RNA 1 (HOXD-AS1) in HCC cells based on transcriptome analysis. The Cancer Geno...
Ahmadi, Majid Hajialilo, Mehrzad Dolati, Sanam Eghbal-Fard, Shadi Heydarlou, Hanieh Ghaebi, Mahnaz Ghassembaglou, Arezou Aghebati-Maleki, Leili Samadi Kafil, Hossein Kamrani, Amin
...
Published in
Journal of cellular biochemistry
Ankylosing spondylitis (AS) is an inflammatory rheumatic disease with increased bone mass in the main sites of inflammation. Regulatory T (Treg) cells have been reported to involve in pathology of AS. This study designed at investigating the effects of nanocurcumin on Treg cell responses in peripheral blood (PB) of AS patients. Test group including...
Yin, Yun-Zhi Zheng, Wei-Hua Zhang, Xin Chen, Yan-Hao Tuo, Yan-Hong
Published in
Journal of cellular biochemistry
Hepatocellular carcinoma (HCC) remains the most common malignant tumor worldwide. Long noncoding RNAs can modulate various tumorigenic processes. In addition, growing evidence has indicated tha the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway is activated in multiple cancers, including HCC. Recently, it was found...
Tan, Hailin Zhang, Guiming Yang, Xuecheng Jing, Tao Shen, Daqing Wang, Xinsheng
Published in
Journal of cellular biochemistry
Prostate cancer (PC) is one of the most common malignant tumors in man. Peimine (PM) is a bioactive substance isolated from Fritillaria. Previous studies have shown that PM could inhibit the occurrence of a variety of cancers. However, the roles of PM in PC and its related mechanism have not been elucidated. Calcium (Ca2+ ) is an important intracel...
Bai, Qian Shao, Jinping Cao, Jing Ren, Xiuhua Cai, Weihua Su, Songxue George, Sanjeeth Tan, Zhiyong Zang, Weidong Dong, Tieli
...
Published in
Journal of cellular biochemistry
Previous studies have found that increased expression of Nav1.9 and protein kinase C (PKC) contributes to pain hypersensitivity in a couple of inflammatory pain models. Here we want to observe if PKC can regulate the expression of Nav1.9 in dorsal root ganglion (DRG) in rheumatoid arthritis (RA) pain model. A chronic knee joint inflammation model w...
Zhang, Zhe Wang, Wei Liu, Jian-Bo Wang, Ying Hao, Jin-Dong Huang, Yi-Jie Gao, Yan Jiang, Hao Yuan, Bao Zhang, Jia-Bao
...
Published in
Journal of cellular biochemistry
MicroRNAs (miRNAs) take part in a variety of biological processes by regulating target genes. Transforming growth factor β receptor 1 (TGFBR1) and TGFBR2 are crucial members of the TGF-β family and are serine/threonine kinase receptors. The aim of this study was to explore the functions of ssc-miR-204 in porcine preadipocyte differentiation and apo...
