Grade 1 vertebral fractures, bone mineral density, and the risk of fractures.
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
The Effect of Biochemical Remission on Bone Metabolism in Cushing's Syndrome: A 2-Year Follow-Up Study.
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Anabolic Window-Like Phenomenon After Biochemical Remission in Cushing's Syndrome: Does Surge in Bone Turnover Markers C...
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Reply to: Grade 1 vertebral fractures, bone mineral density, and the risk of fractures.
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Clearance of Senescent Cells From Injured Muscle Abrogates Heterotopic Ossification in Mouse Models of Fibrodysplasia Os...
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease caused by mutations in activin A receptor type I/activin-like kinase 2 (ACVR1/ALK2), a bone morphogenetic protein (BMP) type I receptor, resulting in the formation of extraskeletal or heterotopic ossification (HO) and other features consistent with premature aging. During the fir...
Systematic review of major osteoporotic fracture to hip fracture incidence rate ratios worldwide: implications for Fract...
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
The Fracture Risk Assessment Tool (FRAX) is the most widely used tool for fracture prediction. It provides 10-year probabilities for hip and major osteoporotic fracture (MOF). It uses country-specific hip fracture incidence and life expectancy data, and for most countries, MOF/hip fracture incidence rate ratios (IRRs) from Malmo Sweden. However, th...
Individualized Bone-Protective Management in Long-Term Cancer Survivors With Bone Metastases.
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Antiresorptive therapy is an important component of a multimodal approach to treating patients with advanced malignancies and metastatic bone disease. Over the past decade, overall survival of affected patients has improved in most cancer entities, and long-term disease control is a realistic goal in many cases. There are emerging clinical studies ...
Early inhibition of subchondral bone remodeling slows load-induced posttraumatic osteoarthritis development in mice.
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Posttraumatic osteoarthritis (PTOA) is associated with abnormal and increased subchondral bone remodeling. Inhibiting altered remodeling immediately following joint damage can slow PTOA progression. Clinically, however, inhibiting remodeling when significant joint damage is already present has minimal effects in slowing further disease progression....
Runt-related transcription factor-2 (Runx2) is required for bone matrix protein gene expression in committed osteoblasts...
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Runt-related transcription factor-2 (Runx2) is an essential transcription factor for osteoblast differentiation. However, its functions after the commitment into osteoblasts are controversial and remain to be clarified. We generated enhanced green fluorescent protein (EGFP)-Cre transgenic mice driven by the 2.3-kilobase (kb) Col1a1 promoter, and Ru...
Serum 25-hydroxyvitamin D is associated with fracture risk only during periods of seasonally high levels in women with a...
Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Serum 25-hydroxyvitamin D (S-25OHD) is used to assess vitamin D status and is known to be affected by season and fat mass. Because these factors are often ignored when interpreting S-25OHD, assessment of vitamin D associations with disease outcomes may be distorted. We aimed to investigate the impact of season of blood draw and fat mass on the asso...
