Liu, Huan Huang, Wei Liu, Jinbo Zhao, Na Wang, Hongyu
Published in
Journal of Vascular Research
Whether arteriosclerosis can influence the hypertension control remains incompletely understood. We hypothesized that higher arteriosclerosis may be associated with uncontrolled hypertension. Arteriosclerosis was assessed by carotid femoral artery pulse wave velocity (CF-PWV) and uncontrolled hypertension (systolic blood pressure [BP] ≥130 mm Hg or...
Daniere, Charlotte Louart, Guillaume Louart, Benjamin Bacle, Marylène Bazalgette, Florian Perez Martin, Antonia Muller, Laurent Lefrant, Jean-Yves Roger, Claire
Published in
Journal of Vascular Research
Background: Microcirculatory alterations have been observed at the early phase of sepsis, although macrocirculation seems preserved. The aim of this study was to analyze the effect of crystalloid fluid therapy on mesenteric microcirculation, assessed by using the confocal laser endomicroscope Cellvizio®, in an endotoxic porcine model. Methods: It i...
Thomas, Shelby Manivannan, Sathiyanarayanan Garg, Vidu Lilly, Brenda
Published in
Journal of Vascular Research
Pulmonary arterial hypertension (PAH) is a chronic progressive disease with significant morbidity and mortality. The disease is characterized by vascular remodeling that includes increased muscularization of distal blood vessels and vessel stiffening associated with changes in extracellular matrix deposition. In humans, chronic hypoxia causes PAH, ...
Stewart, Nathan R. Heiston, Emily M. Miller, Stephanie L. Ballantyne, Anna C. Cheema, Udeyvir S. Spaeth, Andrea M. Kokkinos, Peter Malin, Steven K.
Published in
Journal of Vascular Research
Introduction: Nocturnal systolic blood pressure (SBP) dipping is independently related to cardiovascular disease risk, but it is unclear if vascular insulin sensitivity associates with SBP dipping in patients with metabolic syndrome (MetS). Methods: Eighteen adults with MetS (ATP III criteria 3.3 ± 0.6; 53.2 ± 6.5 years; body mass index 35.8 ± 4.5 ...
Eguchi, Ryoji Kawabe, Jun-ichi Wakabayashi, Ichiro
Published in
Journal of Vascular Research
Tumors induce angiogenesis to acquire oxygen and nutrition from their adjacent microenvironment. Tumor angiogenesis has been believed to be induced primarily by the secretion of vascular endothelial growth factor-A (VEGF-A) from various tumors. VEGF-A binds to VEGF receptor 2 (VEGFR2), resulting in subsequent activation of cellular substances regul...
Song, Fang-Qiang Zhou, Hui-Min Ma, Wei-Xuan Li, Yu-Lin Hu, Bo-Ang Shang, Yuan-Yuan Wang, Zhi-Hao Zhong, Ming Zhang, Wei Ti, Yun
...
Published in
Journal of Vascular Research
Cell death-inducing DFF45-like effector C (CIDEC) is involved in diet-induced adipose inflammation. Whether CIDEC plays a role in diabetic vascular inflammation remains unclear. A type 2 diabetic rat model was induced by high-fat diet and low-dose streptozotocin. We evaluated its characteristics by metabolic tests, Western blot analysis of CIDEC an...
Novak, Rudjer Hrkac, Stela Salai, Grgur Bilandzic, Josko Mitar, Luka Grgurevic, Lovorka
Published in
Journal of Vascular Research
Extracellular matrix proteins are regulated by metzincin proteases, like the disintegrin metalloproteinases with thrombospondin motifs (ADAMTS) family members. This review focuses on the emerging role which ADAMTS-4 might play in vascular pathology, which has implications for atherosclerosis and vessel wall abnormalities, as well as for the resulti...
Kawtharany, Lynn Bessueille, Laurence Issa, Hawraa Hamade, Eva Zibara, Kazem Magne, David
Published in
Journal of Vascular Research
Inflammatory cells and cytokines are known for long to worsen the development of atherosclerotic plaques in mice, and intense efforts are today devoted to develop anti-inflammatory therapeutic strategies to slow down plaque development. Increasing data indicate that plaque inflammation is intimately associated with microcalcifications, which exert ...
Nakayama, Hironobu Inada, Hiroyasu Inukai, Tatsuya Kondo, Kenta Hirai, Kazuyuki Tsutsumi, Tomonari Adachi, Yoshiyuki Nagi-Miura, Noriko Ohno, Naohito Suzuki, Koji
...
Published in
Journal of Vascular Research
Introduction and Objective: Kawasaki disease (KD) is associated with diffuse and systemic vasculitis of unknown aetiology and primarily affects infants and children. Intravenous immunoglobulin (IVIG) treatment reduces the risk of developing coronary aneurysms, but some children have IVIG-resistant KD, which increases their risk of developing corona...
Costa, Gerusa Shushanof, Milenna Bouskela, Eliete Bottino, Daniel
Published in
Journal of Vascular Research
Objective: The aim of this study was to investigate the effect of oral supplementation with L-arginine on serum biochemical profile, blood pressure, microcirculation, and vasoreactivity/endothelial function in young controls, and elderly women with and without type 2 diabetes mellitus (T2DM). Methods: Healthy young (n = 25), healthy elderly (n = 25...
