Robert L. Brent, MD, PhD (1927–2021)
Published in Journal of Perinatal Medicine
Protein and genetic expression of CDKN1C and IGF2 and clinical features related to human umbilical cord length
Published in Journal of Perinatal Medicine
BackgroundUmbilical cord (UC) abnormalities are related to neurological outcome and death; specific molecular factors that might be involved are, as yet, unknown; however, protein-coding genes insulin-like growth factor 2 (IGF2) and cyclin-dependent kinase inhibitor 1C (CDKN1C) have been identified as potential candidates.MethodsAn analytical obser...
Clinical chorioamnionitis at term X: microbiology, clinical signs, placental pathology, and neonatal bacteremia – implic...
...Published in Journal of Perinatal Medicine
ObjectivesClinical chorioamnionitis at term is considered the most common infection-related diagnosis in labor and delivery units worldwide. The syndrome affects 5–12% of all term pregnancies and is a leading cause of maternal morbidity and mortality as well as neonatal death and sepsis. The objectives of this study were to determine the (1) amniot...
Disorders of placental villous maturation are present in one-third of cases with spontaneous preterm labor
...Published in Journal of Perinatal Medicine
ObjectivesSpontaneous preterm labor is an obstetrical syndrome accounting for approximately 65–70% of preterm births, the latter being the most frequent cause of neonatal death and the second most frequent cause of death in children less than five years of age worldwide. The purpose of this study was to determine and compare to uncomplicated pregna...
Effects of COVID-19 pandemic on breastfeeding rates in a neonatal intensive care unit
Published in Journal of Perinatal Medicine
ObjectivesTo find out if the expressed breast milk delivery rate to neonatal intensive care unit (NICU) for babies who were hospitalized for any reason other than COVID-19, and exclusive breastfeeding (EB) rates between discharge date and 30th day of life of those babies were affected by COVID-19 pandemic.MethodsBabies who were hospitalized before ...
‘Getting to zero’ cross transmission of SARS-CoV-2 in obstetric ultrasound during COVID-19 pandemic
Published in Journal of Perinatal Medicine
Implications of the vaginal microbiome and potential restorative strategies on maternal health: a narrative review
Published in Journal of Perinatal Medicine
The vaginal microbiome undergoes dramatic shifts before and throughout pregnancy. Although the genetic and environmental factors that regulate the vaginal microbiome have yet to be fully elucidated, high-throughput sequencing has provided an unprecedented opportunity to interrogate the vaginal microbiome as a potential source of next-generation the...
Women with high plasma levels of PBDE-47 are at increased risk of preterm birth
...Published in Journal of Perinatal Medicine
ObjectivesNearly 100% of North American women have detectable levels of flame retardants such as polybrominated diphenyl ethers (PBDEs) in their plasma. These molecules have structural homology to thyroid hormones and may function as endocrine disruptors. Thyroid dysfunction has previously been associated with increased risk for preterm birth. Ther...
How fever is defined in COVID-19 publications: a disturbing lack of precision
Published in Journal of Perinatal Medicine
ObjectivesFever is the single most frequently reported manifestation of COVID-19 and is a critical element of screening persons for COVID-19. The meaning of “fever” varies depending on the cutoff temperature used, the type of thermometer, the time of the day, the site of measurements, and the person’s gender and race. The absence of a universally a...
Systematic screening for SARS-CoV-2 in pregnant women admitted for delivery: not as easy as it sounds
Published in Journal of Perinatal Medicine
