Paketçi, Ahu Demir, Korcan Tüfekçi, Özlem Acar, Sezer Abacı, Ayhan Yılmaz, Şebnem Böber, Ece
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: Similar autoimmune processes (defective T-cell function) take place during the pathogenesis of aplastic anemia (AA) and Graves’ disease (GD). Antithyroid drugs used for the management of GD may induce AA and GD may occur following treatment of severe aplastic anemia (SAA). Case presentation: Clinical and laboratory investigations were p...
Yang, Hongbo Wang, Linjie Qiu, Xiaonan Yan, Kemin Gong, Fengying Zhu, Huijuan Pan, Hui
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: Recombinant human growth hormone (rhGH) replacement therapy is usually stopped after linear growth completion in patients with growth hormone deficiency. In patients with multiple pituitary hormone deficiency (MPHD), the long-term effects of discontinuation of rhGH replacement are unknown. Methods: In this study, the anthropometric and ...
Thirunagari, Rajeev Marrone, Alexandra Elsinghorst, Hannah Mastrandrea, Lucy D.
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: Provocative growth hormone (GH) stimulation testing is used to evaluate short stature and growth failure in children. Agents commonly used for testing include clonidine, arginine and glucagon. While stimulation testing is generally considered safe, gross hematuria has been described as a rare idiopathic complication of GH stimulation te...
Pehlivantürk Kızılkan, Melis Akgül, Sinem Derman, Orhan Kanbur, Nuray
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: The negative impact of anorexia nervosa (AN) on bone health is well defined. However, there are very few studies evaluating the effect of constitutional thinness on bone health, especially in the adolescent period and in the male gender. The aim of this study is to compare the bone mineral density (BMD) measurements of adolescents with ...
Butler, Éadaoin M. Derraik, José G.B. Taylor, Rachael W. Cutfield, Wayne S.
Published in
Journal of Pediatric Endocrinology and Metabolism
Obesity is highly prevalent in children under the age of 5 years, although its identification in infants under 2 years remains difficult. Several clinical prediction models have been developed for obesity risk in early childhood, using a number of different predictors. The predictive capacity (sensitivity and specificity) of these models varies gre...
Lane, Laura C. Flowers, Josephine Johnstone, Helen Cheetham, Tim
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: There is little adult height data in patients with familial male-limited precocious puberty (FMPP) and no management consensus. We assessed the treatment and adult height in local patients with FMPP and those reported in the literature. Methods: Growth data were obtained on four local patients with FMPP and a search performed to obtain ...
Bocca, Gianni Kuitert, Mirije W.B. Sauer, Pieter J.J. Corpeleijn, Eva
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: The effects of multidisciplinary treatment programs on eating behavior in overweight preschool-aged children are largely unknown. We evaluated a multidisciplinary intervention program on eating behavior in 3- to 5-year-old overweight children, comparing them with children given standard treatment. We also assessed the parental eating be...
Polak, Michel Konrad, Daniel Tønnes Pedersen, Birgitte Puras, Gediminas Šnajderová, Marta
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: We investigated time trends in age, gender, growth hormone (GH) dose and height standard deviation score (SDS) in children with GH deficiency (GHD), born small for gestational age (SGA) or with Turner syndrome (TS) starting GH treatment. Methods: Data were obtained from children enrolled in the NordiNet® International Outcome Study (IOS...
Yoon, Jong Seo So, Cheol Hwan Lee, Hae Sang Hwang, Jin Soon
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: The diagnostic cutoff points for indicators of type 2 diabetes mellitus (T2DM) in the pediatric population have not been defined thus far. Methods: A retrospective, single-center study was conducted from April 2003 to May 2016. We enrolled 236 overweight or obese children and adolescents aged 4–17 years. Thirty-nine (26.9%) of 145 patie...
Wojcicki, Janet M. Prather, Aric A. Epel, Elissa Wang, Dan Dubal, Dena B.
Published in
Journal of Pediatric Endocrinology and Metabolism
Background: Klotho serum levels reflect nutritional state in adults including obesity and anorexia. The relationship between cord blood klotho levels at birth and parameters of growth including anthropometrics are not known. Methods: We evaluated the relationship between cord blood klotho, leptin and adipocyte hormones and infant, child and materna...
