Dong, Li Xin, Xin Chang, Hsun-Ming Leung, Peter C. K. Yu, Chen Lian, Fang Wu, Haicui
Published in
Journal of Ovarian Research
Background Infertility is a global reproductive-health problem, and diminished ovarian reserve (DOR) is one of the common causes of female infertility. Long noncoding RNAs (lncRNAs) are crucial regulators of numerous physiological and pathological processes in humans. However, whether lncRNAs are involved in the development of DOR remains to be elu...
Chen, Yijie Deng, Miao Chen, Zhaojing Han, Shuyang Chen, Jun Zhang, Hongyan Wang, Qianwen Jin, Xuejing Liu, Wenhua Zhang, Zhifen
...
Published in
Journal of Ovarian Research
Background Insulin-like peptide 5 (INSL5) is involved in both reproductive and metabolic processes in polycystic ovary syndrome (PCOS). This study aimed to evaluate the relationship between INSL5 and anti-Müllerian hormone (AMH). Methods A retrospective case–control study was conducted in a university-based reproductive centre between December 2019...
Yin, Guoshu Chen, Fu Chen, Guishan Yang, Xiaoping Huang, Qingxia Chen, Lan Chen, Minjie Zhang, Weichun Ou, Miaoqiong Cao, Man
...
Published in
Journal of Ovarian Research
To characterize the gut bacteriome, mycobiome and serum metabolome profiles in polycystic ovary syndrome (PCOS) patients with normal/overweight individuals and evaluate a potential microbiota-related diagnostic method development for PCOS, 16S rRNA and ITS2 gene sequencing using 88 fecal samples and 87 metabolome analysis from serum samples are con...
Zeng, Cheng Lu, Ruihui Li, Xin Kuai, Yanrong Wang, Sheng Xue, Qing
Published in
Journal of Ovarian Research
Background The possible impact of ovarian endometriomas (OMAs) on in vitro fertilization (IVF) outcomes remains controversial. Therefore, this study aimed to assess the impact of OMAs on IVF cycle parameters, including ovarian reserve and response to stimulation, embryo quality and pregnancy outcomes. Methods This retrospective cohort study include...
Chhabria, Sagar Takle, Vaishnavi Sharma, Nripen Kharkar, Prashant Pansare, Kshama Tripathi, Anish Tripathi, Ashish Bhartiya, Deepa
Published in
Journal of Ovarian Research
Background Fertility preservation and restoration in cancer patients/survivors is the need of present times when increased numbers of patients get cured of cancer but face infertility as a serious side effect. Resveratrol has beneficial effects on chemoablated ovaries and testes in mice but has failed to enter the clinics because of extremely poor ...
Bose, Shree Yao, Haipei Huang, Qiang Whitaker, Regina Kontos, Christopher D Previs, Rebecca A Shen, Xiling
Published in
Journal of ovarian research
Epithelial ovarian cancer (OC) is the most lethal gynecological malignancy and patients present with significant metastatic burden, particularly to the adipose-rich microenvironment of the omentum. Recent evidence has highlighted the importance of metabolic adaptations in enabling this metastasis, leading to significant interest in evolving the ars...
Wu, Dandan Liu, Jia Yu, Liji Wu, Shaofang Qiu, Xiaomei
Published in
Journal of Ovarian Research
Background Ovarian cancer is a common cause of death among women and a health problem worldwide. Circ_0000144 has been confirmed to be an oncogene involved in cancer progression, such as gastric cancer. However, the role of circ_0000144 in ovarian cancer remains unclear and needs to be elucidated. This retrospective study aimed to investigate the u...
Zhang, Chuanxin Dong, Xueqi Yuan, Xinyi Song, Jinzhu Wang, Jiawei Liu, Boyang Wu, Keliang
Published in
Journal of Ovarian Research
Background In mammals, oocytes display compromised quality after experiencing a process of postovulatory aging. However, the mechanisms underlying are not yet fully understood. Here, we portrayed a protein expression profile of fresh and aging metaphase II (MII) mouse oocytes by means of four-dimensional label-free quantification mass spectrometry ...
Bowolaksono, Anom Sundari, Ayu Mulia Fauzi, Muhammad Maidarti, Mila Wiweko, Budi Mutia, Kresna Iffanolida, Pritta Ameilia Febri, Ririn Rahmala Dwiranti, Astari Funahashi, Hiroaki
...
Published in
Journal of ovarian research
Recently, as a delayed childbearing trend is emerging in modern women's adulthood, diminished reproductive potential due to age-related changes is more prevalent. Reduction in the abundance of mitochondrial DNA (mtDNA) copies and circulating anti-Müllerian hormone (AMH) have been separately reported with aging, contributing to the decrease in succe...
Tian, Lifeng Xia, Leizhen Wu, Qiongfang
Published in
Journal of Ovarian Research
Background This large-cohort, retrospective study investigates the relationship between the number of oocytes retrieved and the clinical outcomes for patients receiving the GnRH-a prolonged protocol (mGnRH-a protocol) for fertilization in vitro or intracytoplasmic sperm injection–embryo transfer (IVF/ICSI-ET) treatment. Results We categorized 18,27...
