Yang, Jingfan Huang, Sizhe Cheng, Mengyuan Tan, Weiqing Yang, Junlin
Published in
Journal of Orthopaedic Surgery and Research
Background Adolescent idiopathic scoliosis (AIS) is the most prevalent type of scoliosis affecting children between the ages of 10–16 years. However, risk factors for AIS, particularly the modifiable ones, are still largely unknown. This study aims to investigate the associations of lifestyle and social environment factors with AIS in Chinese schoo...
Wang, Zhen Mao, Haijun Xu, Guangyue
Published in
Journal of Orthopaedic Surgery and Research
Background Accurate preoperative diagnosis of infected nonunion remains a challenge. Here, we evaluated the diagnostic potential of novel biomarkers for infected nonunion. Methods A cohort of 275 patients who underwent surgery for suspected septic nonunion after open reduction and internal fixation were enrolled. Preoperatively analyzed clinical pa...
Wang, Ziyu Chen, Lu Li, Qinghui Zhang, Hengshuo Shan, Yu Qi, Linzeng Wang, Hongliang Chen, Yunzhen
Published in
Journal of Orthopaedic Surgery and Research
Objective The association between the single-nucleotide polymorphisms (SNPs) rs28742109, rs12955018, rs987850, rs8093805, rs12965084 and rs145497186 related to gene named NADH dehydrogenase [ubiquinone] flavoprotein 2 (NDUFV2) and lumbar disc degeneration (LDD) was preliminary investigated in a small sample size. Methods A total of 46 patients with...
Wang, Jianyu Wei, Yuchi Zhou, Zhenwei Yang, Jie Jia, Yuyan Wu, Hailong Dong, Haisi Leng, Xiangyang
Published in
Journal of Orthopaedic Surgery and Research
Background Deer antler is a traditional Chinese medicine with the function of tonifying kidney and strengthening bone, which is often used to treat orthopedic diseases. Methods Eight-week-old C57BL/6 mice were used as the fixation model of open tibial fracture with intramedullary nail. The mice were treated with deer antler extract (DAE) or PBS by ...
Wu, Zhan-Xiong Ren, Wen-Xia Wang, Zhi-Qiang
Published in
Journal of Orthopaedic Surgery and Research
Background Knee osteoarthritis (KOA) with varus alignment and medial space stenosis is a common degenerative disorder in the elderly. To reallocate the force bearing from the medial to the lateral compartment, the anti-varus osteotomy, including high tibial osteotomy (HTO) and proximal fibular osteotomy (PFO), corrects the mechanical lines of lower...
Hung, Chun-Yu Yeh, Chia-Yi Wen, Po-Chong Yeh, Wen-Ling Lin, Shih-Jie
Published in
Journal of Orthopaedic Surgery and Research
Background Studies have reported mixed results on the importance of medial calcar support for the treatment of proximal humeral fractures. The purpose of this study was to compare radiographic and functional outcomes of patients who had displaced proximal humeral fractures with varying levels of medial support. Methods We performed a retrospective ...
Zhao, Chao Dong, Conglei Wang, Xiaomeng Kong, Lingce Chang, Bo Wang, Fei
Published in
Journal of Orthopaedic Surgery and Research
Purpose To investigate the change of the cross-sectional area (CSA) of vastus medialis oblique (VMO) in patients with recurrent patellar dislocation (RPD) treated by tibial tubercle transfer combined with medial patellofemoral ligament (MPFL) reconstruction by imaging methods, and to guide clinical treatment and rehabilitation. Methods From October...
Mochizuki, Tomoharu Ushiki, Takashi Watanabe, Satoshi Omori, Go Kawase, Tomoyuki
Published in
Journal of Orthopaedic Surgery and Research
Background Regenerative therapy using platelet-rich plasma (PRP), a rich source of growth factors, has become popular in orthopedic sports medicine. Elite athletes prefer PRP therapy for their injured muscles and tendons primarily to avoid the possible risks of surgical treatment. However, the clinical effectiveness of PRP therapy in elite athletes...
Piedade, Sérgio Rocha Górios, Carlos Migliorini, Filippo Maffulli, Nicola
Published in
Journal of Orthopaedic Surgery and Research
Different surgical techniques have been proposed to reconstruct combined anterior cruciate (ACL) and lateral collateral ligaments (LCL). Although these surgical techniques are reliable and reproducible, the number of autologous grafts needed for the reconstruction could be a limiting factor, especially when patients present with multi-ligament knee...
Wang, Bing Yao, Li Dong, Yuefu Liu, Jian Wu, Jian
Published in
Journal of Orthopaedic Surgery and Research
Background LncRNA PCED1B-AS1 (PCED1B-AS1) promotes glioma. This study aimed to investigate its role in osteosarcoma (OS). Methods The study included 60 OS patients. Accumulation of miR-10a and PCED1B-AS1 in tissues from OS patients and cell lines was determined by RT-qPCR. Cell transfections were performed for interaction analysis. Participation of...
