Chung, Mei Zhao, Naisi Meier, Richard Koestler, Devin C. Wu, Guojun de Castillo, Erika Paster, Bruce J. Charpentier, Kevin Izard, Jacques Kelsey, Karl T.
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Published in
Journal of Oral Microbiology
Background : Oral microbiota is believed to play important roles in systemic diseases, including cancer. Methods : We collected oral samples (tongue, buccal, supragingival, and saliva) and pancreatic tissue or intestinal samples from 52 subjects, and characterized 16S rRNA genes using high-throughput DNA sequencing. Results : Bray–Curtis plot showe...
Thanh Nguyen, Hoa Zhang, Rouyu Inokawa, Naoki Oura, Takahiro Chen, Xinyue Iwatani, Shun Niimi, Kyoko Niimi, Masakazu Holmes, Ann Rachel Cannon, Richard David
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Published in
Journal of Oral Microbiology
Introduction : Candida albicans is an opportunistic pathogen that causes oral candidiasis. A previous study showed that Bgl2p and Ecm33p may mediate the interaction between the yeast and saliva-coated hydroxyapatite (SHA; a model for the tooth surface). This study investigated the roles of these cell wall proteins in the adherence of C. albicans to...
Ionescu, Andrei Cristian Brambilla, Eugenio Manzoli, Lamberto Orsini, Giovanna Gentili, Valentina Rizzo, Roberta
Published in
Journal of Oral Microbiology
Objective : We designed an in vitro study to evaluate the efficiency of an 0.5 vol% hydrogen peroxide-based spray in reducing Coronavirus 229E spread during a conventional dental procedure. Methods : A class III cabinet-like chamber was custom-built, using phantoms for both patient and operator. A suspension of HCoV-229E in artificial saliva having...
Alsaegh, Mohammed Amjed Varma, Sudhir Rama Altaie, Alaa Muayad Zhu, Shengrong
Published in
Journal of Oral Microbiology
Background: The factor behind the activation of the remnant odontogenic tissues and development of odontogenic cysts and tumors is poorly understood.This study aimed to investigate the presence of human cytomegalovirus (HCMV) in dentigerous cyst (DC), odontogenic keratocyst (OKC), and ameloblastoma (AB). Methods: The study included 41 samples, whic...
Holmer, Jacob Aho, Velma Eriksdotter, Maria Paulin, Lars Pietiäinen, Milla Auvinen, Petri Schultzberg, Marianne Pussinen, Pirkko J. Buhlin, Kåre
Published in
Journal of Oral Microbiology
Aim : The aim of this study was to compare the subgingival microbiota of people with Alzheimer´s disease (AD), mild cognitive impairment (MCI), subjective cognitive decline (SCD) and cognitively healthy individuals. Materials and methods : The study population was recruited from 2013 to 2017 and comprised 132 cases recently diagnosed with AD (n = 4...
Mohamed Elashiry, Mohamed Tian, Fucong Elashiry, Mahmoud Zeitoun, Rana Elsayed, Ranya Andrews, Matthew L. Bergeon, Brian E. Cutler, Christopher Tay, Franklin
Published in
Journal of Oral Microbiology
Background : The macrophage is an innate immune defense cell involved in pathogen recognition and clearance. Aim : In view of the diversity of the macrophage phenotype and function, the present study investigated how Enterococcus faecalis infection affects the differentiation, phenotype and cytokine profile of macrophages. Methods : Murine bone mar...
Willis, Jesse R. Iraola-Guzmán, Susana Saus, Ester Ksiezopolska, Ewa Cozzuto, Luca Bejarano, Luis A. Andreu-Somavilla, Nuria Alloza-Trabado, Miriam Puig-Sola, Anna Blanco, Andrea
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Published in
Journal of Oral Microbiology
Introduction : The oral cavity harbors an abundant and diverse microbial community (i.e. the microbiome), whose composition and roles in health and disease have been the focus of intense research. Down syndrome (DS) is associated with particular characteristics in the oral cavity, and with a lower incidence of caries and higher incidence of periodo...
Chen, Juxiu Chen, Zhanyi Yuan, Keyong Huang, Zhengwei Mao, Mengying
Published in
Journal of Oral Microbiology
Bacteriophage T4 RNA ligase 1 (T4 Rnl1) can be stably expressed in many bacteria and has been reported to affect the bioactivity of the host bacteria. Recently, we constructed bacteriophage T4 Rnl1 expressing system in Streptococcus mutans, a crucial biofilm-forming and dental caries-causing oral pathogen. Here, we characterized the function of rec...
Seers, Christine A. Mahmud, A. Sayeed M. Huq, N. Laila Cross, Keith J. Reynolds, Eric C.
Published in
Journal of Oral Microbiology
Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis , a keystone pathogen in the development of destructive periodontal disease. The gingipains function as proteinases and transpeptidases utilising small peptides such as glycylglycine as acceptor molecule...
Gopinath, Divya Kunnath Menon, Rohit Chun Wie, Chong Banerjee, Moinak Panda, Swagatika Mandal, Deviprasad Behera, Paresh Kumar Roychoudhury, Susanta Kheur, Supriya George Botelho, Michael
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Published in
Journal of Oral Microbiology
Objective : While some oral carcinomas appear to arise de novo , others develop within long-standing conditions of the oral cavity that have malignant potential, now known as oral potentially malignant disorders (OPMDs). The oral bacteriome associated with OPMD has been studied to a lesser extent than that associated with oral cancer. To characteri...
