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Anti-MOG associated disease with intracranial hypertension after COVID-19 vaccination.

Published in Journal of neurology

Measuring the functional impact of cognitive impairment in Huntington's disease.

Published in Journal of neurology

Patients with Huntington's disease (HD) exhibit a variable predominance of cognitive, behavioral and motor symptoms. A specific instrument focusing on the impact of cognitive impairment in HD over functional capacity is lacking. To address the need for a brief and specifically developed HD questionnaire able to capture functional aspects suspected ...

Serum neurofilament light chain, contactin-1 and complement activation in anti-MAG IgM paraprotein-related peripheral ne...

Published in Journal of neurology

In anti-myelin-associated glycoprotein IgM paraprotein-related peripheral neuropathy (anti-MAG PN), there is a lack of reliable biomarkers to select patients eligible for therapy and for evaluating treatment effects, both in routine practice and in clinical trials. Neurofilament light chain (NfL) and contactin-1 (CNTN1) can serve as markers of axon...

Time to onset and duration of botulinum toxin efficacy in movement disorders.

Published in Journal of neurology

Botulinum toxin (BoNT) is a valuable treatment in movement disorders; however, time to onset and duration of efficacy may widely differ among patients. We aimed to clarify the impact of main demographic and clinical features on time to onset and duration of BoNT efficacy. We analyzed time-to-onset and duration of BoNT efficacy in 186 consecutive pa...

Undetected ophthalmological disorders in Parkinson's disease.

Published in Journal of neurology

Ophthalmological disorders are common and frequently disabling for people with Parkinson's disease (PD). However, details on the prevalence, severity and impact of ophthalmological disorders thus far lacking. We aimed to identify PD patients with undetected ophthalmological disorders in a large cross-sectional, observational study. We previously de...

Global morbidity and mortality of central nervous system tuberculosis: a systematic review and meta-analysis.

Published in Journal of neurology

Tuberculosis (TB) is the second most common cause of death due to a single infectious agent worldwide after COVID-19. Up to 15% of the cases are extrapulmonary, and if it is located in the central nervous system (CNS-TB), it presents high morbidity and mortality. Still, the global epidemiology of CNS-TB remains unknown. To estimate the global preva...

Reversible cerebral vasoconstriction syndrome after intravenous iron substitution: a case report.

Published in Journal of neurology

Home-monitoring of vital capacity in people with a motor neuron disease.

Published in Journal of neurology

Home-monitoring of spirometry has the potential to improve care for patients with a motor neuron disease (MND) by enabling early detection of respiratory dysfunction and reducing travel burden. Our aim was to evaluate the validity and feasibility of home-monitoring vital capacity (VC) in patients with MND. We included 33 patients with amyotrophic l...

Cognitive, EEG, and MRI features of COVID-19 survivors: a 10-month study.

Published in Journal of neurology

To explore cognitive, EEG, and MRI features in COVID-19 survivors up to 10 months after hospital discharge. Adult patients with a recent diagnosis of COVID-19 and reporting subsequent cognitive complaints underwent neuropsychological assessment and 19-channel-EEG within 2 months (baseline, N = 49) and 10 months (follow-up, N = 33) after hospital di...

Imaging-based outcome prediction in posterior circulation stroke.

Published in Journal of neurology

We developed a machine learning model to allow early functional outcome prediction for patients presenting with posterior circulation (pc)-stroke based on CT-imaging and clinical data at admission. The proposed algorithm utilizes quantitative information from automated multidimensional assessments of posterior circulation Acute Stroke Prognosis Ear...