Demetz, Matthias Krigers, Aleksandrs Moser, Patrizia Kerschbaumer, Johannes Thomé, Claudius Freyschlag, Christian F.
Published in
Journal of Neuro-Oncology
Purpose Data on differences in overall survival and molecular characteristics between incidental (iLGG) and symptomatic lower grade Glioma (sLGG) are limited. The aim of this study was to investigate differences between patients with iLGG and sLGG. Methods All adult patients with a histologically proven diffuse (WHO°II) or anaplastic (WHO°III) glio...
Voon, Noor Shatirah Manan, Hanani Abdul Yahya, Noorazrul
Published in
Journal of Neuro-Oncology
Background Glioma irradiation often unavoidably damages the brain volume and affects cognition. This study aims to evaluate the relationship of remote cognitive assessments in determining cognitive impairment of irradiated glioma patients in relation to the quality of life and MRI changes. Methods Thirty patients (16–76 aged) with two imaging (pre-...
Dincer, Alper Morales-Valero, Saul F Robert, Stephanie M Tabor, Joanna K O'Brien, Joseph Yalcin, Kanat Fulbright, Robert K Erson-Omay, Zeynep Dunn, Ian F Moliterno, Jennifer
...
Published in
Journal of neuro-oncology
Surgical resection has long been the treatment of choice for meningiomas and is considered curative in many cases. Indeed, the extent of resection (EOR) remains a significant factor in determining disease recurrence and outcome optimization for patients undergoing surgery. Although the Simpson Grading Scale continues to be widely accepted as the me...
Ius, Tamara Sabatino, Giovanni Panciani, Pier Paolo Fontanella, Marco Maria Rudà, Roberta Castellano, Antonella Barbagallo, Giuseppe Maria Vincenzo Belotti, Francesco Boccaletti, Riccardo Catapano, Giuseppe
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Published in
Journal of neuro-oncology
The extent of resection (EOR) is an independent prognostic factor for overall survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology section of the Italian Society of Neurosurgery (SINch®) was to provide a general overview of the current trends and technical tools to reach this goal. A systematic review was perform...
Wamelink, Ivar J. H. G. Hempel, Hugo L. van de Giessen, Elsmarieke Vries, Mark H. M. De Witt Hamer, Philip Barkhof, Frederik Keil, Vera C.
Published in
Journal of Neuro-Oncology
Purpose To gain insight into how patients with primary brain tumors experience MRI, follow-up protocols, and gadolinium-based contrast agent (GBCA) use. Methods Primary brain tumor patients answered a survey after their MRI exam. Questions were analyzed to determine trends in patients’ experience regarding the scan itself, follow-up frequency, and ...
Liang, Lun Wen, Liangbao Qin, Shixing He, Zhenqiang Lu, Jie Cui, Run Jiang, Xiaobing Hu, Hongrong Zhong, Sheng Li, Chang
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Published in
Journal of Neuro-Oncology
Backgound Neurosurgical resection is a standard local treatment for lung cancer brain metastases (BMs). This study aims to investigate whether neurosurgical resection provides survival benefit in lung cancer BMs with poor KPS. Materials and methods This multicenter retrospective study included 386 lung cancer BMs with pretreatment KPS ≤ 70 among a ...
Quach, Stefanie Schwartz, Christoph Aumiller, Maximilian Foglar, Marco Schmutzer, Michael Katzendobler, Sophie El Fahim, Mohamed Forbrig, Robert Bochmann, Katja Egensperger, Rupert
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Published in
Journal of neuro-oncology
Innovative, efficient treatments are desperately needed for people with glioblastoma (GBM). Sixteen patients (median age 65.8 years) with newly diagnosed, small-sized, not safely resectable supratentorial GBM underwent interstitial photodynamic therapy (iPDT) as upfront eradicating local therapy followed by standard chemoradiation. 5-aminolevulinic...
Thierheimer, Marisa Cioffi, Gino Waite, Kristin A Kruchko, Carol Ostrom, Quinn T Barnholtz-Sloan, Jill S
Published in
Journal of neuro-oncology
Primary malignant brain and other central nervous system tumors are rare cancers that have shown rising mortality rates in recent years. To elucidate potential factors involved in this rising death rate, we examined mortality trends for primary malignant BT in the United States stratified by histopathology groupings, age, race, and sex. Mortality r...
Bleeker, L. Kouwenhoven, M. C. M. de Heer, I. Lissenberg-Witte, B. I. Gijsbers, A. H. Dubbink, H. J. Kros, J. M. Gijtenbeek, J. M. M. Kurt, E. van der Rijt, C. C. D.
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Published in
Journal of Neuro-Oncology
Purpose Medulloblastoma is a rare tumor in adults. The objective of this nationwide, multicenter study was to evaluate the toxicity and efficacy of the Dutch treatment protocol for adult medulloblastoma patients. Methods Adult medulloblastoma patients diagnosed between 2010 and 2018 were identified in the Dutch rare tumors registry or nationwide pa...
Jusino, Shirley Fadul, Camilo E. Dillon, Patrick
Published in
Journal of Neuro-Oncology
Introduction Brain metastases are a common cause of morbidity and mortality in patients with breast cancer. Local central nervous system (CNS) directed therapies are usually the first line treatment for breast cancer brain metastases (BCBM), but those must be followed by systemic therapies to achieve long-term benefit. Systemic therapy for hormone ...
