Wang, Wei Shu, Gao-feng Lu, Kong-jun Xu, Xiao-ling Sun, Min-cheng Qi, Jing Huang, Qiao-ling Tan, Wei-qiang Du, Yong-zhong
Published in
Journal of Nanobiotechnology
BackgroundPsoriasis is a chronic immune-mediated inflammatory skin disease without effective treatment. The utilization of all trans-retinoic acid (TRA) and betamethasone (BT) for the treatment of psoriasis is still facing difficulties, due to their relatively poor stability, limited skin permeation, and systemic side effects. Flexible liposomes ar...
Yeor-Davidi, Ella Zverzhinetsky, Marina Krivitsky, Vadim Patolsky, Fernando
Published in
Journal of Nanobiotechnology
BackgroundBacterial biofilms are communities of surface-associated microorganisms living in cellular clusters or micro-colonies, encapsulated in a complex matrix composed of an extracellular polymeric substance, separated by open water channels that act as a circulatory system that enable better diffusion of nutrients and easier removal of metaboli...
Marycz, K. Sobierajska, P. Roecken, M. Kornicka-Garbowska, K. Kępska, M. Idczak, R. Nedelec, J.-M. Wiglusz, R. J.
Published in
Journal of Nanobiotechnology
An amendment to this paper has been published and can be accessed via the original article.
Wu, Yifan Jin, Yang Sun, Tianyu Zhu, Piaoyu Li, Jinlong Zhang, Qinglin Wang, Xiaoke Jiang, Junkang Chen, Gang Zhao, Xinyuan
...
Published in
Journal of Nanobiotechnology
BackgroundMost nanoparticles (NPs) reportedly block autophagic flux, thereby upregulating p62/SQSTM1 through degradation inhibition. p62 also acts as a multifunctional scaffold protein with multiple domains, and is involved in various cellular processes. However, the autophagy substrate-independent role of p62 and its regulation at the transcriptio...
Gu, Jiayi Chen, Yuming Tong, Ling Wang, Xueling Yu, Dehong Wu, Hao
Published in
Journal of Nanobiotechnology
An amendment to this paper has been published and can be accessed via the original article.
Zielińska-Górska, Marlena Hotowy, Anna Wierzbicki, Mateusz Bałaban, Jaśmina Sosnowska, Malwina Jaworski, Sławomir Strojny, Barbara Chwalibog, André Sawosz, Ewa
Published in
Journal of Nanobiotechnology
BackgroundFormation of muscular pseudo-tissue depends on muscle precursor cells, the extracellular matrix (ECM)-mimicking structure and factors stimulating cell differentiation. These three things cooperate and can create a tissue-like structure, however, their interrelationships are relatively unknown. The objective was to study the interaction be...
Jin, Jing Zhao, Qijie
Published in
Journal of Nanobiotechnology
Nanoparticles (NPs) have been increasingly studied for radiosensitization. The principle of NPs radio-enhancement is to use high-atomic number NPs (e.g. gold, hafnium, bismuth and gadolinium) or deliver radiosensitizing substances, such as cisplatin and selenium. Nowadays, cancer immunotherapy is emerged as a promising treatment and immune checkpoi...
Shkodra-Pula, Blerina Kretzer, Christian Jordan, Paul M. Klemm, Paul Koeberle, Andreas Pretzel, David Banoglu, Erden Lorkowski, Stefan Wallert, Maria Höppener, Stephanie
...
Published in
Journal of Nanobiotechnology
BackgroundDual inhibitors of the 5-lipoxygenase-activating protein (FLAP) and the microsomal prostaglandin E2 synthase-1 (mPGES-1) may exert better anti-inflammatory efficacy and lower risks of adverse effects versus non-steroidal anti-inflammatory drugs. Despite these advantages, many dual FLAP/mPGES-1 inhibitors are acidic lipophilic molecules wi...
John, Geraldine Sandana Mala Vuttaradhi, Veena Kumari Takeuchi, Satoru Pitani, Ravi Shankar Venkatraman, Ganesh Rayala, Suresh Kumar
Published in
Journal of Nanobiotechnology
BackgroundNordihydroguaiaretic acid (NDGA) is a plant lignan obtained from creosote bush, known to possess anti-oxidant, anti-cancer and anti-viral activities and is being used in traditional medicine. However, toxicity studies indicated liver and kidney damage despite its immense medicinal properties. There has been a recent increase of curiosity ...
Gao, Chunhong Chu, Xiaoyang Gong, Wei Zheng, Jinpeng Xie, Xiangyang Wang, Yuli Yang, Meiyan Li, Zhiping Gao, Chunsheng Yang, Yang
...
Published in
Journal of Nanobiotechnology
BackgroundAlthough many therapeutic strategies for Alzheimer’s disease (AD) have been explored, these strategies are seldom used in the clinic. Therefore, AD therapeutic research is still urgently needed. One major challenge in the field of nanotherapeutics is to increase the selective delivery of drugs to a targeted location. Herein, we devised an...
