Crosby, James Erzuah, Tosha Haider, Mahvish Smith, Forrest Ganti, Shyam Monohan, Gregory Elsouiedi, Raymond
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Journal of Investigative Medicine High Impact Case Reports
Secondary malignancies including leukemia are an increasing concern in patients with prior primary malignancies treated with alkylating agents or topoisomerase II inhibitors. These can also be referred to as therapy-related leukemia. Therapy-related leukemia most commonly results in myelodysplastic syndrome or acute myeloid leukemia. The alkylating...
Kumar, Suneet Grell, Gilda-Rae Joseph, Gardith Wang, Jen C.
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Journal of Investigative Medicine High Impact Case Reports
Amyloidosis rarely presents as localized lymphadenopathy. Various studies have elucidated the varied presentation and manifestations of this interesting disease. We reviewed the literature and found 36 cases of primary amyloidosis with lymph node enlargement as a presentation, and 17 of the 36 cases (47%) had systemic involvement on further work up...
Lyon, Priscilla R. P. Trevathan, Sean Talukdar, Rudranath Nguyen, Dominic D. McPhaul, Christopher M. Rampisela, Debby
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Journal of Investigative Medicine High Impact Case Reports
Extrahepatic metastasis of hepatocellular carcinoma (HCC) to the head and neck is unusual, especially the oral cavity/maxillofacial region. Metastatic HCC to the hard palate, however, is particularly rare. The most common site of HCC metastasis is the lung, followed by lymph nodes, bone, and adrenal gland. Importantly, oral cavity metastatic HCC ma...
Swarath, Steven Maharaj, Nicole Lalchansingh, Dayna Seecheran, Rajeev Seecheran, Valmiki Leyva Quert, Abel Yoandri Seecheran, Naveen Anand
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Journal of investigative medicine high impact case reports
We present the case of a 26-year-old man, without any apparent cardiovascular risk factors, who experienced an ST-segment-elevation acute coronary syndrome after binge drinking high-proof alcohol, which was successfully managed with primary percutaneous coronary intervention and comprehensive, guideline-directed medical therapy.
Hendrickson Rahmlow, Tara Kolagatla, Sandhya Mattingly, Kathleen Grube, Jonathan Ganti, Subramanya Shyam Moka, Nagabhishek
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Journal of Investigative Medicine High Impact Case Reports
Solitary fibrous tumor/hemangiopericytoma (SFT/HPC) is a rare intracranial tumor that arises from pericytes surrounding the blood vessels. Solitary fibrous tumor/hemangiopericytoma accounts for less than 1% of primary brain tumors and is classified as grades I, II, or III based on mitotic count. These tumors often masquerade as meningiomas. Histolo...
Alirezaei, Toktam Irilouzadian, Rana Khani, Mohammad
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Journal of investigative medicine high impact case reports
Aortic dissection is an infrequent diagnosis that usually presents with acute onset of sharp and severe tearing pain. It rarely presents with atypical symptoms, accompanied by a higher mortality risk that arises the delay in diagnosis. In this report, we discuss a type A aortic dissection case with a presentation of heaviness-like chest pain with n...
McHan, Lara Gupta, Jyotsna
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Journal of Investigative Medicine High Impact Case Reports
Acute suppurative thyroiditis is a rare and potentially life-threatening cause of thyroid inflammation requiring prompt recognition and management. There are few reported cases of thyrotoxicosis due to acute suppurative thyroiditis. We are reporting the case of a 9-year-old boy who presented to the emergency room with fevers, neck pain and swelling...
Gaulden, Hannah Dungan, William Romano, John Willner, Ira
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Journal of Investigative Medicine High Impact Case Reports
Doxycycline (DOX) is a tetracycline antibiotic that is prescribed for treating a variety of infections involving the skin, respiratory tract, and urogenital system. Adversely, esophageal mucosal injury due to DOX is well described; however, gastric mucosal injury is less commonly reported and may result in severe gastrointestinal hemorrhage and occ...
Crosby, James Semon, Sarah Ganti, Subramanya Shyam Klauber-Choephel, Enid Abraham, James
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Journal of investigative medicine high impact case reports
The Delta variant of COVID-19 has been associated with severe disease causing a surge in the second half of 2021. Atypical pathogens can be present in those in particular with severe ARDS and can contribute to excess morbidity and mortality. We must maintain a high level of suspicion for these pathogens as this can present an opportunity to dramati...
Phillips, Steven M. Pouch, Stephanie M. Lo, Denise J. Kandiah, Sheetal Lomashvili, Koba A. Subramanian, Ram A. Moran, Peter Killian, Alley Kandiah, Prem A.
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Journal of Investigative Medicine High Impact Case Reports
Mycoplasma and Ureaplasma infections have been described as a cause of hyperammonemia syndrome leading to devastating neurological injury in the post-transplant period, most commonly in lung transplant recipients. The occurrence of significant hyperammonemia caused by other urease-producing organisms remains unclear. We describe a case of dissemina...