Published in Journal of Infection and Chemotherapy
Background There are few agents that have been proven effective for COVID-19. Predicting clinical improvement as well as mortality or severity is very important. Objectives This study aimed to investigate the factors associated with the clinical improvement of COVID-19. Methods Overall, 74 patients receiving treatment for COVID-19 at Tokyo Medical ...
Published in Journal of Infection and Chemotherapy
Introduction The Public Health Center (PHC)—known as hokenjo in Japan—assume a crucial role in disease control. Coronavirus disease 2019 (COVID-19) is one of many designated infectious diseases monitored by the agency. During the present pandemic, patients who suspected COVID-19 were instructed to call the Coronavirus Consultation Center in the PHC...
Published in Journal of Infection and Chemotherapy
Introduction Severe coronavirus 2019 disease (CoViD-19) may lead to respiratory failure and mechanical ventilation. Therefore, ventilator associated pneumonia (VAP) may complicate the course of the disease. The aim of the current article was to investigate possible predictive factors for bacterial VAP on a retrospective manner, in a cohort of mecha...
Published in Journal of Infection and Chemotherapy
Introduction Among patients with coronavirus disease 2019 (COVID-19), the factors that affect anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody production remain unclear. This study aimed to identify such factors among patients convalescing from COVID-19. Methods This study comprised patients who had been diagnosed with COV...
Published in Journal of Infection and Chemotherapy
This article aims to examine progress of public health policy regarding global infectious diseases over the past decade in Japan. A narrative review was conducted, overviewing items of the Infectious Disease Committee and the Tuberculosis Committee of the Ministry of Health, Labour and Welfare between 2010 and 2019. The mean value of items discusse...
Published in Journal of Infection and Chemotherapy
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is rapidly spreading all over the world. A new quantifying reagent for detecting SARS-CoV-2 antigen was developed for early and accurate detection. We evaluated the novel quantitative reagent for detecting SARS-CoV-2 antigen using an automated laboratory device. Met...
Published in Journal of Infection and Chemotherapy
Introduction Convalescent plasma transfusion (CPT), a potential therapy for coronavirus disease 2019 (COVID-19), requires strict quality control of the donor blood. Whether to confirm the disappearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA (RNAemia) in convalescent donor blood or not is unclear. Reports recommending th...
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Information on the effectiveness of personal protective equipment (PPE) for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among healthcare workers (HCWs), especially among HCWs with frequent contact with patients with SARS-CoV-2, is limited. We conducted a prospective cohort study on 49 HCWs who worked in close c...
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
As countermeasures against the COVID-19 outbreak, sports and entertainment events were canceled (VEC) in Japan for two weeks from 26 February through 13 March. Moreover, most schools were closed (SC). For this study, we estimated the basic reproduction number (R0) and SC and VEC effects. After constructing a susceptible-infected-recovered model wit...
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
The effect of systemic corticosteroids on clinical outcomes in patients with coronavirus disease 2019 (COVID-19) remains controversial. While the use of corticosteroids raises concerns regarding delayed viral clearance, secondary infections, and long-term complications that can lead to increased mortality, corticosteroids have the potential to redu...
